Griseofulvin

Molecule Description

Griseofulvin is an antifungal agent. It kills the fungi that cause infections o

f the hair, skin, scalp, and nails-ringworm.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Griseofulvin

It is used in the treatment of athlete’s foot (tinea pedis)
Griseofulvin can also be used for treatment of similar ‘tinea infections’ such as:
Tinea capitis (fungal infection of the skin of the scalp, eyebrows)
Tinea corporis (ringworm infection of the hands and legs)
Tinea cruris (also called jock itch – affects the skin of the genitals, thighs, buttocks)
Tinea ungium (fungal infection of the nails or onychomycosis)
Tinea barbae (fungus affects the beard and mustache areas of the face)

Contraindications of Griseofulvin

When should one not use Griseofulvin

If you have an allergy to Griseofulvin or any of the components of the medicine
If you are suffering from liver disease and porphyria (a condition where blood-forming proteins are defective and accumulate, resulting in purplish patches on the skin)
If you are pregnant or breastfeeding

Side effects of Griseofulvin

Common side effects of this drug are:

Headache
Nausea, vomiting, loose motions
Rashes, Sensitivity to light (photosensitivity)
Decrease in a particular type of white blood cells (granulocytopenia)
Blistering and peeling of the skin
Lumpy skin with or without a weeping liquid
Reddening and burning of the skin
Lower back pain
Very pale urine, yellowing of the skin

Precautions and Warnings of Griseofulvin

Pregnancy

Can I take Griseofulvin during pregnancy?

It is not recommended in pregnancy. It may harm your body.

Breast Feeding

Can I take Griseofulvin while breastfeeding?

It is not advised to breastfeed during the treatment. It may harm the newborn baby.

Driving

Can I drive if I have consumed Griseofulvin?

Griseofulvin may not affect your ability to drive. But if you have any symptoms like dizziness, spinning of the head, weakness of hands and legs, or any rashes that are causing discomfort, you are advised not to drive.

Alcohol

Can I consume alcohol with Griseofulvin?

Consumption of alcohol while taking Griseofulvin is not recommended as it can cause s potential side effects such as feeling very sick, red skin, and giddiness.

Other General Warnings

Talk to your doctor if

You are suffering from a rare painful skin and tissue disease called Systemic Lupus Erythematosus (SLE)
You experience severe skin reactions because your skin may become more sensitive to sunlight or ultraviolet (UV) light when taking this medicine
You consume alcohol during the treatment, you may feel sick, may be ill, an irregular heartbeat, and chest or abdominal pain

Mode of Action of Griseofulvin

How Does It Work?

Griseofulvin works by stopping the growth and multiplication of the fungus (trichophyton) that causes athlete’s foot, and thus cures the disease.

Interactions of Griseofulvin

Interactions with other medicines

Medicine used after organ transplantation (Ciclosporin)
Medicines to thin your blood like Warfarin
Medicines used to treat addiction (Methadone)
Pain killers (Phenyl Butazone)
Oral contraceptives
Medicines used to treat convulsions (Primidone)
Doxecalciferol, a vitamin D supplement
Medicines used for sedation, or relief of anxiety

Interactions with food items

Use Griseofulvin with a meal, as it will increase absorption.

Dosage of Griseofulvin

Overdose

Accidental overdose may not be harmful. But inform your doctor if you develop any side effects like skin rashes, sensitivity to light, spinning of the head, weakness, and numbness of hands and feet.

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose and do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Mahesh Muthe

MBBS

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: How long should I take Griseofulvin?

A: Duration of treatment with Griseofulvin depends upon the condition and may vary from 2-4 weeks to 4-6 months. In case of athlete’s foot, Griseofulvin may have to be used for 4-8 weeks.

Q: Is there anything else I should know while using Griseofulvin?

A: Griseofulvin may render hormonal contraceptives less effective. Hence seek advice from your doctor as you may have to use condom, loop, etc. (instead of pills) to avoid pregnancy while you are taking Griseofulvin. Griseofulvin must not be given to a child younger than 2 years of age or a child weighing less than 18 kg.

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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