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Gefitinib

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Molecule Summary

Uses
Non-small cell lung cancer
Therapy
Anti-Neoplastic
Side Effects
Nausea, vomiting, diarrhoea, skin rash
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Molecule Description

Gefitinib is an anti-cancer medication. It is used in the treatment of non-small cell lung cancer (NSCLC).

Uses

For the treatment of non-small cell lung cancer (NSCLC).

Contraindications

When should one not use Gefitinib

  • If you are allergic to gefitinib or any of the ingredients of this medicine
  • If you are breastfeeding

Side effects

Common side effects of this drug are:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Fever
  • Eating disorder
  • Skin rash
  • Itching
  • Redness
  • Loss of appetite
  • Weakness
  • Dry or sore mouth
  • Conjunctivitis
  • Dry eye
  • Hair loss
  • Nail disorder
  • Nosebleed
  • Blood in urine (bleeding)

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information on the use of this medicine in pregnancy. Hence it is recommended not to use the same unless prescribed by your doctor.

Breast Feeding

Breast Feeding

You must not breastfeed while on treatment with this medicine, as it is unknown if gefitinib passes into breast milk

Driving

Driving

You may feel weak during the treatment. So if you experience such symptoms be cautious while driving or operating tools.

Alcohol

Alcohol

There is no known interaction between alcohol and this medicine. However, it is important to consult your physician if you have a habit of regular drinking.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have problems with your lungs
  • You have a history of liver problem
  • You are already taking any other medicines like rifampicin, phenytoin, carbamazepine, warfarin, antacids etc.
  • You develop eye problems
  • You develop stomach and intestinal problems
  • You experience diarrhoea, nausea, vomiting while on treatment, contact the doctor
  • This medicine is not recommended for use in children & adolescents

Mode of Action

How Does It Work?

Gefitinib works by blocking a certain protein which is responsible for the growth of cancer cells. Thus stopping or slowing down the growth of cancer cells.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Gefitinib works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking medicines to treat fungal infections, tuberculosis, fits, sleep problems, psychiatric illnesses or are taking antacids

Dosage

Overdose

  • Symptoms of overdose are diarrhoea, skin rash
  • If you experience any of the symptoms or think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of this medicine, take it as soon as you remember. However, if it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Gefitinib is a medicine with a single active ingredient.

Gefitinib is used for the treatment of non-small cell lung cancer (NSCLC).

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References:

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