Fluvoxamine
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Molecule Description
Fluvoxamine belongs to a group of medicines called Selective Serotonin Reuptake Inhibitors (SSRI). It is an antidepressant. It helps in decreasing unwanted thoughts and urges to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living.
Uses
- It is used to treat depression
- It is also used to treat Obsessive-Compulsive Disorder (OCD)
Contraindications
When should one not use Fluvoxamine
- If you are allergic to Fluvoxamine or any of the other ingredients
- If you are taking other medicines called Monoamine Oxidase Inhibitors (MAOI) sometimes prescribed to treat depression or anxiety-like Linezolid (an antibiotic which is also an MAOI)
- If you are taking Tizanidine, a medicine often used as muscle relaxant
Side effects
Common side effects of this drug are:
- An allergic reaction can also be observed where rash and swelling of face, throat and tongue can be observed
- Breathing trouble and severe dizziness
- Agitation
- Anxiety
- Constipation, diarrhea
- Difficulty in sleeping
- Dry mouth
- Faster heartbeat
- Feeling drowsy (lethargy)
- Feeling unwell
- Headache
- Indigestion
- Loss of appetite
- Nervousness
- Stomach pain
- Sweating
- Tremor
- Muscle weakness
- Vomiting
- Convulsions
- Liver complaints
- Mania (a feeling of happiness or over-excitement)
- Sensitivity to sunlight
- Unexpected milk flow - rare side effect
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- Talk to your doctor if you:
- Recently had a heart attack
- Have epilepsy
- Have a history of bleeding problems
- Have diabetes
- Are having treatment with Electroconvulsive Therapy (ECT)
- Have ever had mania (a feeling of over-excitement)
- Have liver or kidney problems
- Have high pressure in your eyes (glaucoma)
- Are less than 18 years old
Mode of Action
How Does It Work?
Fluvoxamine works by inhibiting the neuronal uptake of Serotonin in the brain by blocking the selective Neuronal Serotonin Reuptake receptors, thereby helps to restore the balance of a natural substance like Serotonin in the brain.
Interactions
Interactions with other medicines
- Antidepressants (like Benzodiazepines, Tricyclic Antidepressants or anti-psychotics)
- Aspirin (Acetylsalicylic Acid) or Aspirin-like medicines, used to treat pain and inflammation (arthritis)
- Ciclosporin used to reduce the activity of the immune system
- Methadone used to treat pain and withdrawal symptoms
- Mexiletine used to treat abnormal heart rhythms
- Phenytoin or Carbamazepine used to treat epilepsy
- Propranolol used to treat high blood pressure and heart conditions
- Ropinirole, for Parkinson’s disease
- Theophylline used to treat asthma and bronchitis
- Tramadol, a pain-killer
- Clopidogrel, Warfarin, used to prevent blood clots
Interactions with food items
Grapefruit juice also increases the amount of Fluvoxamine absorbed by the body which increases the effect of Fluvoxamine.
Dosage
Overdose
Dizziness, vomiting, diarrhea, and nausea are common symptoms of the overdose of Fluvoxamine. Consult your doctor as soon as possible.
Missed a Dose
If you missed a dose, wait until the next dose is due. Do not try to double the dose to make up for the missed dose.
Frequently Asked Questions (FAQs)
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