Enalapril+Hydrochlorothiazide

• Hypertension (high blood pressure)

When should one not use Enalapril+Hydrochlorothiazide

• If you are allergic to enalapril, hydrochlorothiazide or any other ingredients of this medicine.
• If you are taking medicines called sacubitril or valsartan (for Chronic heart failure).
• If you have a history of angioedema (a type of swelling that occurs in the deeper layers of the skin) or anuria (absence of urine production).
• If you are pregnant.

Common side effects of this drug are:

• Blurred vision
• Dizziness
• Cough
• Nausea
• Fatigue

Other General Warnings

• You are pregnant or planning to become pregnant, as enalapril can cause serious harm or death to the unborn baby.
• You have a history of angioedema (severe swelling), especially related to previous ACE inhibitor therapy.
• You are allergic to enalapril or any other ACE inhibitors.
• You have kidney disease or are undergoing dialysis.
• You are breastfeeding or planning to breastfeed.
• You experience dizziness, lightheadedness, or fainting, especially when standing up quickly.
• You have persistent or severe vomiting or diarrhoea, as these can cause a drop in blood pressure.
• You are taking other medications, including over-the-counter drugs and supplements, as they may interact with enalapril.
• You have liver disease.

How Does It Work?

• Enalapril blocks the process that converts angiotensin I into angiotensin II by inhibiting an enzyme called ACE. This action disrupts the body's system that regulates blood pressure and fluid balance, known as the renin-angiotensin-aldosterone system.
• Hydrochlorothiazide acts on the renal tubular mechanism by hindering the reabsorption of electrolytes, which increases the excretion of sodium, chloride, and water, thus reducing blood volume and arterial pressure.

Interactions with other medicines

• Consult your doctor if you are taking other medications used to lower blood pressure, as they may further lower your blood pressure.
• Lithium-containing medicine used for certain brain-related problems, if taken along with this medicine, can lead to increased levels of lithium in the body and toxicity.
• For medicines or supplements containing potassium, frequent monitoring of potassium levels is recommended.
• Other medications such as celecoxib, rofecoxib and etoricoxib (used to reduce pain and inflammation) may interact with this medicine. Consult your doctor.

Overdose

• If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.
• Taking too much of this medicine can lead to electrolyte disturbances, disturbed heart rate, renal failure, fast breathing, palpitations, dizziness, anxiety, and cough.

Missed a Dose