Doxazosin

Molecule Description

Doxazosin is used to treat high blood pressure and improve urine flow due to en

largement of the prostate gland in men. It belongs to a class of medicines called ‘alpha-adrenergic antagonists’ or ‘alpha-blockers.’

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Doxazosin

High blood pressure
Doxazosin can be used alone or in combination with other blood pressure medications
Urinary flow obstruction and other symptoms due to non-cancerous enlargement of the prostate (benign prostatic hypertrophy)
Contraindications
Allergy to Doxazosin or other medicines of the same class (Prazosin, Terazosin, Alfuzosin, Silodosin) or any of its components
If you feel dizzy or light-headed on when you stand up from a sitting or a lying position (orthostatic hypertension)
Patients with enlarged prostate gland but have low blood pressure, blockage, stones or infections of the urinary tract
A condition where the patient is unaware if the bladder is full which results in urinary leak (urinary incontinence) or not producing urine (anuria), with or without kidney disease

Contraindications of Doxazosin

When should one not use Doxazosin

Allergy to Doxazosin or other medicines of the same class (Prazosin, Terazosin, Alfuzosin, Silodosin) or any of its components
If you feel dizzy or light-headed on when you stand up from a sitting or a lying position (orthostatic hypertension)
Patients with enlarged prostate gland but have low blood pressure, blockage, stones or infections of the urinary tract
A condition where the patient is unaware if the bladder is full which results in urinary leak (urinary incontinence) or not producing urine (anuria), with or without kidney disease

Side effects of Doxazosin

Common side effects of this drug are:

Dizziness, spinning of head, low blood pressure, headache
Cough, cold, running nose, nose, throat and lung infections
Stomach pain, indigestion, heartburn, dry mouth
Back pain, itching, muscle aches, fever (flu-like symptoms)
Urinary infections, leaking urine, weakness, sleepiness,
constipation, loose motions, gas in stomach, joint pains, difficulty in urine and increased passing of urine, joint pain, sleeplessness, anxiety, altered sense of touch and sensation (hands and feet),...
Read more
Breathing difficulty, irregular heartbeats (including pounding or palpitations), chest pain, yellowing of eyes (jaundice), low blood cell counts, painful erection of the penis

Precautions and Warnings of Doxazosin

Pregnancy

Can I take Doxazosin during pregnancy?

There is no safety data available on this medicine during pregnancy. Doxazosin has to be used in pregnant women only if it cannot be replaced.

Breast Feeding

Can I take Doxazosin while breastfeeding?

Tiny amounts of Doxazosin is secreted in breast milk. Hence, this medicine can be used in breastfeeding women if no other alternatives are available.

Driving

Can I drive if I have consumed Doxazosin?

Doxazosin can make you feel weak or dizzy, mostly when you start taking medicine. Do not drive in the first few weeks. You may drive later in the absence of such symptoms.

Alcohol

Can I consume alcohol with Doxazosin?

Taking alcohol with this medicine may lead to cause more dizziness or drowsiness.

Other General Warnings

Talk to your doctor if

You have liver and heart diseases
You are planning for eye surgeries (cataract)

Mode of Action of Doxazosin

How Does It Work?

Alpha-adrenergic receptors (proteins that receive and transmit signals) cause narrowing of blood vessels and the neck of the urinary bladder. Doxazosin acts by blocking these receptor proteins and rel...

Interactions of Doxazosin

Interactions with other medicines

Medicines used to treat erectile dysfunction (Sildenafil, Tadalafil, Vardenafil)
Antifungals and antibacterials (like Itraconazole, Ketoconazole, Clarithromycin, Telithromycin, Voriconazole)
Medicines used to treat HIV/AIDS (protease inhibitors such as Indinavir, Ritonavir, Nelfinavir, Saquinavir)
Nefazodone (an antidepressant)

Interactions with food items

Doxazosin can be taken with or without meals.

Dietary Restrictions of Doxazosin

Low salt diet is preferable.

Dosage of Doxazosin

Overdose

Unintentional overdose may not be harmful. Overdose with Doxazosin will cause low blood pressure and symptoms like drowsiness, dizziness, lightheadedness, fainting (seizure in severe cases). Seek medi...

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose and do not take extra medicine or double dose to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Mansi Savla

B. Pharm, PharmD

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What else should I know before taking Doxazosin?

Dizziness and fainting may occur in the initial stages when a patient is started on Doxazosin, especially when standing up from a sitting or a lying position. Get up slowly from sitting or lying down ...
Read more
Doxazosin should not be given to children and adolescents below 18 years of age
Talk to your doctor if you are 65 years or older

Q: Is Doxazosin effective for high blood pressure and symptoms of prostate enlargement?

Doxazosin has been demonstrated to be a safe and well-tolerated medicine for high blood pressure and to relieve symptoms of enlarged prostate, even when used for an extended period
This medicine is of special benefit in patients who have both the conditions and is usually given in combination with other medicines
Doxazosin is not recommended in cancerous enlargements of the prostate gland
Take Doxazosin under medical supervision. Do not self-medicate or self-adjust the dose

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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