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molecule

Doxazosin

Molecule Description

Doxazosin is used to treat high blood pressure and improve urine flow due to en

largement of the prostate gland in men. It belongs to a class of medicines called ‘alpha-adrenergic antagonists’ or ‘alpha-blockers.’

uses

Uses of Doxazosin

  • High blood pressure
  • Doxazosin can be used alone or in combination with other blood pressure medications
  • Urinary flow obstruction and other symptoms due to non-cancerous enlargement of the prostate (benign prostatic hypertrophy)
  • Contraindications
  • Allergy to Doxazosin or other medicines of the same class (Prazosin, Terazosin, Alfuzosin, Silodosin) or any of its components
  • If you feel dizzy or light-headed on when you stand up from a sitting or a lying position (orthostatic hypertension)
  • Patients with enlarged prostate gland but have low blood pressure, blockage, stones or infections of the urinary tract
  • A condition where the patient is unaware if the bladder is full which results in urinary leak (urinary incontinence) or not producing urine (anuria), with or without kidney disease
contraindications

Contraindications of Doxazosin

When should one not use Doxazosin

  • Allergy to Doxazosin or other medicines of the same class (Prazosin, Terazosin, Alfuzosin, Silodosin) or any of its components
  • If you feel dizzy or light-headed on when you stand up from a sitting or a lying position (orthostatic hypertension)
  • Patients with enlarged prostate gland but have low blood pressure, blockage, stones or infections of the urinary tract
  • A condition where the patient is unaware if the bladder is full which results in urinary leak (urinary incontinence) or not producing urine (anuria), with or without kidney disease
sideEffects

Side effects of Doxazosin

Common side effects of this drug are:

  • Dizziness, spinning of head, low blood pressure, headache
  • Cough, cold, running nose, nose, throat and lung infections
  • Stomach pain, indigestion, heartburn, dry mouth
  • Back pain, itching, muscle aches, fever (flu-like symptoms)
  • Urinary infections, leaking urine, weakness, sleepiness,
  • constipation, loose motions, gas in stomach, joint pains, difficulty in urine and increased passing of urine, joint pain, sleeplessness, anxiety, altered sense of touch and sensation (hands and feet),...
    Read more
  • Breathing difficulty, irregular heartbeats (including pounding or palpitations), chest pain, yellowing of eyes (jaundice), low blood cell counts, painful erection of the penis
precautionsAndWarnings

Precautions and Warnings of Doxazosin

pregnancy

Pregnancy

Q:
Can I take Doxazosin during pregnancy?
A:
There is no safety data available on this medicine during pregnancy. Doxazosin has to be used in pregnant women only if it cannot be replaced.
breastfeeding

Breast Feeding

Q:
Can I take Doxazosin while breastfeeding?
A:
Tiny amounts of Doxazosin is secreted in breast milk. Hence, this medicine can be used in breastfeeding women if no other alternatives are available.
driving

Driving

Q:
Can I drive if I have consumed Doxazosin?
A:
Doxazosin can make you feel weak or dizzy, mostly when you start taking medicine. Do not drive in the first few weeks. You may drive later in the absence of such symptoms.
alcohol

Alcohol

Q:
Can I consume alcohol with Doxazosin?
A:
Taking alcohol with this medicine may lead to cause more dizziness or drowsiness.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • You have liver and heart diseases
  • You are planning for eye surgeries (cataract)
modeOfAction

Mode of Action of Doxazosin

How Does It Work?

Alpha-adrenergic receptors (proteins that receive and transmit signals) cause narrowing of blood vessels and the neck of the urinary bladder. Doxazosin acts by blocking these receptor proteins and rel...
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interactions

Interactions of Doxazosin

Interactions with other medicines

  • Medicines used to treat erectile dysfunction (Sildenafil, Tadalafil, Vardenafil)
  • Antifungals and antibacterials (like Itraconazole, Ketoconazole, Clarithromycin, Telithromycin, Voriconazole)
  • Medicines used to treat HIV/AIDS (protease inhibitors such as Indinavir, Ritonavir, Nelfinavir, Saquinavir)
  • Nefazodone (an antidepressant)

Interactions with food items

Doxazosin can be taken with or without meals.
dietaryRestrictions

Dietary Restrictions of Doxazosin

Low salt diet is preferable.
dosage

Dosage of Doxazosin

Overdose

Unintentional overdose may not be harmful. Overdose with Doxazosin will cause low blood pressure and symptoms like drowsiness, dizziness, lightheadedness, fainting (seizure in severe cases). Seek medi...
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Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose and do not take extra medicine or double dose to compensate for the missed dose.

Content Details

WRITTEN BY
doctor

Dr. Mansi Savla

B. Pharm, PharmD

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: What else should I know before taking Doxazosin?

  • Dizziness and fainting may occur in the initial stages when a patient is started on Doxazosin, especially when standing up from a sitting or a lying position. Get up slowly from sitting or lying down ...
    Read more
  • Doxazosin should not be given to children and adolescents below 18 years of age
  • Talk to your doctor if you are 65 years or older

Q: Is Doxazosin effective for high blood pressure and symptoms of prostate enlargement?

  • Doxazosin has been demonstrated to be a safe and well-tolerated medicine for high blood pressure and to relieve symptoms of enlarged prostate, even when used for an extended period
  • This medicine is of special benefit in patients who have both the conditions and is usually given in combination with other medicines
  • Doxazosin is not recommended in cancerous enlargements of the prostate gland
  • Take Doxazosin under medical supervision. Do not self-medicate or self-adjust the dose
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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