Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone

Uses	Painful muscle spasm, pain and inflammation of muscles, joints and bones
Therapy	Muscle Relaxant, Analgesic/Antipyretic
Side Effects	Dizziness, lightheadedness, nausea, vomiting, weakness

100% Authentic
Medicines

Cash on delivery
available

Delivery across
19k pincodes

Molecule Description

Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is a combination medication used to treat pain and muscle stiffness associated with conditions such as arthritis, spondylitis and injuries. It contains diclofenac, paracetamol, and chlorzoxazone, which work by reducing inflammation and relaxing muscles. This medicine must be taken as directed by the doctor, in doses, and for the duration prescribed. Take it regularly at a fixed time. Do not skip a dose or consume more than that recommended by the doctor. Also, do not abruptly discontinue this medicine without first consulting your doctor. Before initiating treatment with this medicine, you should let the doctor know if you are pregnant, planning a pregnancy or breastfeeding. And inform the doctor of your detailed medical history.

Uses

Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is used for relieving pain and inflammation of muscles, joints and bones in conditions such as arthritis, spondylitis and injuries.
It is also used for relieving pain, inflammation and swelling post surgeries and operations.

Contraindications

When should one not use Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone

If you are allergic to diclofenac, paracetamol, chlorzoxazone, or any ingredient in the Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone.
If you are experiencing bleeding from the stomach and intestine or have an active peptic ulcer.
If you are allergic to other painkillers such as aspirin and have experienced severe asthma, rashes or any other allergy.
If you have severe heart failure.
If you have severe kidney or liver problems.
If you are pregnant.
This medicine should not be used to relieve pain before, during, and after bypass surgery of the heart.

Side effects

Common side effects of this drug are:

Dizziness
Lightheadedness
Nausea
Vomiting
Weakness
Fatigue
Liver problem
Headache
Rash

Precautions and Warnings

Pregnancy

It is unsafe to take this medicine during pregnancy. Hence, it should not be taken by pregnant women. Taking this medicine during pregnancy can cause defects in the baby's heart or even delay of delivery or increase the risk of bleeding.

Breast Feeding

Components of this medicine pass into the breast milk and there is limited information regarding the safety of this medicine during breastfeeding. Hence it is advised not to use this medicine if you are breastfeeding.

Driving

It is not advised to drive or use machines while using this medicine as components of this medicine may cause dizziness and even affect your ability to drive.

Alcohol

It is advised to avoid the consumption of alcohol during the treatment as it may worsen your liver problems and other side effects.

Other General Warnings

Talk to your doctor if

You have kidney or liver problems.
You have heart problems like high blood pressure and heart failure.
You are an elderly patient or taking diuretics or have a kidney disorder, this medicine can increase the risk of kidney failure.
Your doctor may ask you to do renal function tests for the same.
You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease, or you are passing black tarry stools.
You have asthma, and this medicine can worsen the same.
You have Systemic lupus erythematosus (an autoimmune disorder).
If you are an alcoholic, then concomitant use of this medicine can damage the liver.
You have disorders related to blood, like clotting problems and anaemia.
You have skin rashes & lesions after taking this medicine.

Mode of Action

How Does It Work?

Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone works by combining the three components. Diclofenac and Paracetamol inhibit the synthesis of prostaglandins, which are responsible for causing pain, swelling, and inflammation; thus, they offer anti-inflammatory properties. Chlorzoxazone is a muscle relaxant that works by blocking the signals of painful sensation through the nerve to the brain and reduces pain and stiffness.

Interactions

Interactions with other medicines

Do not take any other medicines containing Paracetamol or Diclofenac, as there is a risk of liver damage.
If you are taking medicines for high blood pressure, this medicine can interfere with their effect.
Medicines like water pills can lead to kidney damage when taken along with it.
Caution is needed if you are taking medicines to treat heart failure.
This medicine can increase the levels of lithium and methotrexate. Discuss this with your doctor before starting the treatment.
Medicines used to modify immune response during organ transplant, like ciclosporin & tacrolimus, can result in kidney damage if taken with this medicine.
Increased risk of stomach ulcers or bleeding when taken with steroids or other pain relief medicines like Aspirin.
There is a risk of bleeding if you are taking blood-thinning medicines like Warfarin and Coumarin.
There is an increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin.
If you are taking medicines to treat diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs.
Medicines used to treat fits, seizures & depression, like Phenobarbital, Carbamazepine, Phenytoin, and Clonazepam, should be used with caution as this medicine can increase the side effects of these medicines.
Medicines used to treat gout, like Probenecid, bacterial infections, like Chloramphenicol and rifampicin, and HIV infections, like Zidovudine, should be used cautiously.

Interactions with food items

It is advisable to take Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone with or after food to reduce the risk of stomach upset. Spicy and heavy meals should be avoided to reduce side effects like nausea and vomiting.

Dosage

Overdose

Taking Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone in high doses may result in symptoms of overdose like headache, nausea, vomiting and stomach pain. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Do not take a double dose if you have missed the dose, take the next dose as soon as you remember.

Frequently Asked Questions (FAQs)

Yes, Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is a painkiller medicine specifically used for pain related to musculoskeletal conditions.

You are supposed to tell the doctor your health condition like if you have diabetes, blood disorders, liver disease or kidney disease.

Do not take this medicine without consulting your dentist. The underlying cause of toothache can be different. Therefore, do not self-medicate.

Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone contains Paracetamol, Diclofenac and Chlorzoxazone. Paracetamol and Diclofenac reduce the production of chemicals responsible for inflammation and pain. Chlorzoxazone helps in relaxing the muscles and improves pain and stiffness caused by muscle strains and sprains.

No, it is not safe to take any other medicines to relieve pain along with this medicine. Concomitant use of painkillers can cause adverse effects like gastrointestinal bleeding and liver damage.

Gastritis is a condition that affects the lining of the stomach causing pain and inflammation. It is caused due to infection, use of certain medicines, injury, etc. Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is a medicine used to relieve pain due to muscle spasms and may not be effective for gastritis.

No, Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is not effective for relieving period pain. It is used to relieve pain due to muscle spasms.

No, the medicine must not be taken for headaches or conditions other than what it is prescribed for. Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is used for relieving pain and inflammation of musculoskeletal conditions.

Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone starts working within 30-40 minutes of its oral administration. However, if you do not feel improvement, inform the doctor but you should not consume more than the recommended daily dose by the doctor.

No, It is not a steroid. Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is a pain-relieving medicine with muscle relaxant properties and is used for the treatment of painful muscle spasms associated with musculoskeletal conditions.

Avoid taking Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone without consulting the dentist. The underlying cause of toothache can be different. Do not self-medicate.

Sometimes individuals might experience acidity, stomach ache or other symptoms of stomach discomfort after taking this medicine.

Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone may make you dizzy and drowsy/sleepy. Please consult your doctor before use. It is recommended to avoid driving, operating any complex machinery or performing any other tasks that require mental alertness if you experience these symptoms after taking this medicine.

Yes, sometimes you may experience dizziness as a side effect, although not everyone gets it.

No, Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone is not effective in stomach aches. It helps in relieving painful muscle spasms associated with musculoskeletal conditions.

No, Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone should not be taken for the long term unless told by the doctor. It is usually prescribed for a short duration. Do not exceed the maximum daily doses and treatment durations recommended.

No, Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone does not help in controlling loose motion or diarrhoea. Diarrhoea can be caused due to multiple reasons such as consuming contaminated food or due to some underlying condition. Consult your doctor for advice and do not take any medicine on your own.

Your doctor will recommend if it is suitable for you to take Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone for tissue or ligament injury. It is recommended to follow your doctor's instructions and avoid self-medication.

Some individuals may experience constipation with the use of Diclofenac Sodium+Paracetamol/Acetaminophen+Chlorzoxazone. This effect is generally mild and usually goes away with time. It is recommended to drink enough fluids and eat more fibre foods during that duration. However, if this effect persists or worsens, please talk to your doctor.

Articles

View All

Did you find this helpful?

References:

U.S. National Library of Medicine. Acetaminophen [Internet]. Bethesda (MD): National Institutes of Health; 2024 [cited 4 Jun 2026].

Explore More at Pharmeasy

Why trust PharmEasy?

# ONE OF INDIA'S MOST TRUSTED HEALTHCARE PLATFORM

CODAvailable

100%Genuine Medicine

30 DAYReturn Policy

Making medicines affordable, authentic, and easily accessible across India

700+100% Genuine & verified medicines

70,000+Medicine orders everyday

70 MillionTotal customer served

70 MillionDelivery hubs & fulfillment centre

7000Trained & trusted delivery partners