Leprosy iLeprosytagious (that can spread from person to person) is an infectious disease caused by a bacteria called Mycobacterium Leprae. It is a slowly developing disease, and it takes 2-6 years , The disease causes patches on the skin, reduced sensation, tingling and numbness, vision problems (due to nerve damage) and also damages the lining of the upper respiratory tract (nose and the throat) , The disease is transmitted from person to person, mostly by contact or air , Any skin lesions (infections) with loss of sensation and mostly associated with thickened nerve is Leprosy , There are broadly two types of Leprosy – Lepromatous Leprosy (or Multibacillary Leprosy) where the bacterial load is high and Tuberculoid (or Leprobacillary) Leprosy where the bacterial load is low , Leprosy is not a very common disease nowadays, with less than 10,000 cases worldwide

Clofazimine

Molecule Description

Clofazimine is an antibiotic that is used to treat Leprosy, an infectious bacte

rial disease which affects the skin, nerves, eyes and the lining of the nose and throat.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Clofazimine

It is used in the treatment of Leprosy, and to treat flare-ups of leprosy along with the combination of other medicines.

Contraindications of Clofazimine

When should one not use Clofazimine

If you have allergy to Clofazimine or any components of the medicine
If you are suffering from liver, stomach, and intestinal problems

Side effects of Clofazimine

Common side effects of this drug are:

Reversible skin discoloration
Discoloration of hair, eyes, tears, sweat, sputum, feces and urine
Stomach pain (feeling sick), nausea, loose motions, loss of appetite
Dry, rough and scaly skin, rashes and itching

Precautions and Warnings of Clofazimine

Pregnancy

Can I take Clofazimine during pregnancy?

Enough data is not available. Clofazimine has the potential to cause skin discoloration of the unborn baby and should be given in pregnancy only if other alternatives are not available.

Breast Feeding

Can I take Clofazimine while breastfeeding?

Clofazimine should not be given to breastfeeding mothers as this medicine secretes in breast milk can cause skin discoloration of the baby.

Driving

Can I drive if I have consumed Clofazimine?

Clofazimine does not affect your ability to drive. But, caution is advised in the presence of side effects such as dizziness, tiredness, or decreased alertness.

Alcohol

Can I consume alcohol with Clofazimine?

Interactions of Clofazimine with alcohol are not known, but Leprosy is a disease that is difficult to cure and relapses often. Alcohol delays healing and suppresses immunity, and it is advised to avoid alcohol during the treatment.

Other General Warnings

Talk to your doctor if

Clofazimine may make your skin more sensitive so avoid going out in direct sunlight in the afternoons, or wear protective clothing or apply sunscreen lotions
High doses should not be given for an extended period (more than 3 months) as it can result in intestinal problems, which can be serious

Mode of Action of Clofazimine

How Does It Work?

Clofazimine works by attacking the DNA (genetic material) of the disease causing bacteria and affects the multiplication of the bacteria, thus controlling Leprosy.

Interactions of Clofazimine

Interactions with other medicines

Some medicines which may interact with Clofazimine and need to be used with caution
Bedaquiline (treats TB)
Antacids – that reduce stomach acidity (aluminum hydroxide, magnesium hydroxide)
Phenytoin (for seizures)
Also, inform your doctor if you are taking any over-the-counter medicines or herbal medicines as they may have interactions

Interactions with food items

Clofazimine has to be taken with food or milk.

Dietary Restrictions of Clofazimine

Do not eat oranges or drink orange juice.

Dosage of Clofazimine

Overdose

Unintentional overdose is unlikely to be harmful. But if you develop any symptoms like skin rashes, itching, stomach problems, inform your doctor.

Missed a Dose

Clofazimine is usually given once a day in combination with other medicines. Hence it is advised to take this medicine strictly without missing any dosages. If you miss taking other medicines also, yo...

Q: What causes Leprosy?

Leprosy iLeprosytagious (that can spread from person to person) is an infectious disease caused by a bacteria called Mycobacterium Leprae. It is a slowly developing disease, and it takes 2-6 years
The disease causes patches on the skin, reduced sensation, tingling and numbness, vision problems (due to nerve damage) and also damages the lining of the upper respiratory tract (nose and the throat)
The disease is transmitted from person to person, mostly by contact or air
Any skin lesions (infections) with loss of sensation and mostly associated with thickened nerve is Leprosy
There are broadly two types of Leprosy – Lepromatous Leprosy (or Multibacillary Leprosy) where the bacterial load is high and Tuberculoid (or Leprobacillary) Leprosy where the bacterial load is low
Leprosy is not a very common disease nowadays, with less than 10,000 cases worldwide

Q: Does Clofazimine cure Leprosy?

Leprosy is a curable disease, but it requires treatment with multiple medicines. Any single medicine cannot cure Leprosy, and a combination of medicines has to be given
The preferred combination is Rifampicin, Clofazimine, and Dapsone
Clofazimine is given in conjunction with other medicines for the treatment of Lepromatous Leprosy (or Multibacillary Leprosy), in mild or severe forms
In many cases, Leprosy can be cured, and the duration of treatment can vary between 6-12 months

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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