Chlorhexidine+Metronidazole

Uses	Mouth infections
Therapy	Dental Care
Side Effects	Dryness of the mouth, irritation, burning sensation, metallic taste, staining of the teeth

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Molecule Description

Chlorhexidine+Metronidazole is used for the treatment of mouth infections. Chlorhexidine+Metronidazole is a combination of two active ingredients - metronidazole and chlorhexidine. The combined action of these two medicines is effective against a wide range of oral infection-causing germs and is therefore useful for the treatment of a variety of mouth infections. Chlorhexidine+Metronidazole is meant for topical use only. You may rarely experience side effects like dryness of the mouth, irritation, burning sensation, metallic taste and staining of the teeth. These side effects are usually mild and will go away in some time. However, if the side effects persist or if your condition worsens, you should contact your doctor immediately. This medicine is not to be used in children less than 6 years of age. Use it exactly as directed by your doctor.

Uses

Chlorhexidine+Metronidazole is used for the treatment of mouth infections.

Contraindications

When should one not use Chlorhexidine+Metronidazole

If you are allergic to metronidazole, chlorhexidine or any other ingredient of Chlorhexidine+Metronidazole.
If you are pregnant or breastfeeding.
If you are less than 6 years of age.

Side effects

Common side effects of this drug are:

Dryness of the mouth
Irritation
Burning sensation
Metallic taste
Staining of the teeth

Precautions and Warnings

Pregnancy

There is limited information available regarding the effect of Chlorhexidine+Metronidazole in pregnancy. However, to avoid the possible risks to the baby, it is recommended that this medicine should not be used during pregnancy.

Breast Feeding

Limited information is available regarding the effect of Chlorhexidine+Metronidazole on human breastmilk. Thus, to avoid the potential risks to the suckling infant, Chlorhexidine+Metronidazole should not be used by breastfeeding women.

Driving

There is no influence of Chlorhexidine+Metronidazole on the ability to drive, as this medicine is a topical preparation.

Alcohol

No, alcohol should not be taken along with Chlorhexidine+Metronidazole. The simultaneous use of Chlorhexidine+Metronidazole and alcohol may cause side effects like burning sensation, reddening of the skin, increase in body temperature, nausea, vomiting, rashes and itching, throbbing headache, vision disturbances, dizziness, sweating, uneasiness and confusion.

Other General Warnings

Talk to your doctor if

You develop swelling, soreness or irritation of the mouth after using this medicine that persists for a long time.
You use a toothpaste or tooth powder that contains anionic agents.
You drink alcoholic beverages regularly or often.

Mode of Action

How Does It Work?

Chlorhexidine+Metronidazole is a combination of two active ingredients - metronidazole and chlorhexidine.
Metronidazole is an antibiotic that acts by altering the bacteria growth and undergoes certain changes that make it cytotoxic to the bacteria (capable of destroying the bacteria). It also interacts with the genetic material of bacteria and prevents bacterial multiplication. Thus, this stops the further growth of bacteria and kills the bacteria causing the mouth infection.
Chlorhexidine causes a change in the structure of the cell membrane of bacteria and fungi. This change in the cell membrane causes a number of membrane abnormalities causing leakage of the components of the cell leading to cell death. This stops the further growth of the bacteria and fungi and treats the infections of the mouth.

Interactions

Interactions with other medicines

Since this medicine is to be used topically, it is less likely to interact with other medicines. However, you should tell your doctor if you are taking other medicines, herbal preparations, or supplements.
Care should be taken when using Chlorhexidine+Metronidazole along with coumarin anticoagulants (warfarin) as the activity of the anticoagulant in the body is increased.
Taking disulfiram while using Chlorhexidine+Metronidazole can cause confusion.

Dosage

Overdose

Chlorhexidine+Metronidazole is meant for local application and hence the cases of overdose are unlikely. However, upon accidental ingestion, visit the nearest hospital or contact your doctor immediately. If you have overapplied this medicine, wipe out the excess medicine with tissue or cotton.

Missed a Dose

You should never miss your dose of medicines. However, if you missed any application of Chlorhexidine+Metronidazole, apply it as soon as you remember. If it's time for your next application, then skip the missed application and continue with your regular application schedule. Do not overapply to compensate for the missed application. If you have any further questions, please talk to your doctor.

Frequently Asked Questions (FAQs)

Chlorhexidine+Metronidazole is used for the treatment of a wide variety of mouth infections and dental conditions such as plaque, maintaining oral hygiene, inflammation of gums, oral ulcers, etc.

Like all medicines, the use of Chlorhexidine+Metronidazole may also produce side effects in some individuals. Thus in some individuals, the use of this medicine may cause staining of the teeth as a side effect. The side effects are usually mild and go away in some time. However, if it persists for a long time, please consult with your doctor.

No, please do not stop using this medicine on your own without consulting your doctor. Use it exactly as directed by your doctor. Do not use more than the prescribed amount. Please do not change the dose or stop using this medicine before the prescribed duration, even if you feel better.

Chlorhexidine+Metronidazole is meant for external use only. Use it as directed by your doctor. Wash your hands thoroughly before and after applying the medicine. You should not eat or drink anything for 30 minutes after applying this medicine.

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Chlorhexidine+Metronidazole

Molecule Summary