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Nimesulide+Tizanidine

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Molecule Summary

Uses
Pain and inflammation
Therapy
Muscle Relaxant, Analgesic
Side Effects
Nausea, diarrhoea, dry mouth, drowsiness
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Molecule Description

Nimesulide+Tizanidine is a medicine used to relieve pain and inflammation. It contains nimesulide and tizanidine as active ingredients. It is used to relieve pain and inflammation associated with various conditions and muscle spasms. This medicine inhibits the formation of chemicals in the body responsible for pain and inflammation. Nimesulide+Tizanidine must be taken in the doses and duration as prescribed by the doctor. Take it with food to avoid an upset stomach.

Uses

  • For the treatment of muscle spasms associated with pain.
  • To treat pain and inflammation associated with various conditions such as surgery, dental, skin conditions, etc.

Contraindications

When should one not use Nimesulide+Tizanidine

  • If you are allergic to nimesulide, tizanidine, or other ingredients in Nimesulide+Tizanidine.
  • If you have a history or suffer from liver disease.
  • If you have a history or suffer from severe kidney disease.
  • If you have pumping disorders of the heart.
  • If you have ulcers in the stomach or the first part of the small intestine (duodenum), a history of bleeding the digestive tract and the stomach, history of recurrent ulcers in the stomach.
  • If you have low salt, blood or fluid level.

Side effects

Common side effects of this drug are:

  • Nausea
  • Diarrhoea
  • Stomach discomfort
  • Dry mouth
  • Drowsiness
  • Rash

Precautions and Warnings

Pregnancy

Pregnancy

There is no adequate information available on the use of Nimesulide+Tizanidine in pregnancy, thus it must not be used during pregnancy. Please consult your doctor if you are pregnant and think you may be or are planning a pregnancy before using this medicine.

Breast Feeding

Breast Feeding

It is not known if components of Nimesulide+Tizanidine pass into the breastmilk. To avoid undesirable effects in the breastfed infant the medicine is not recommended in a breastfeeding woman.

Driving

Driving

Avoid driving if you experience dizziness and weakness after taking Nimesulide+Tizanidine.

Alcohol

Alcohol

Avoid consuming alcohol while taking Nimesulide+Tizanidine as it may worsen the side effect. Consult the doctor if you have a regular habit of drinking.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are pregnant or planning for a pregnancy or are breastfeeding.
  • You suffer from digestive system-related disorders like ulceration, sores or bleeding in the stomach, severe heart and kidney-related disorders.
  • You experience allergic reactions.
  • The medicine must be used cautiously in individuals with kidney, heart or liver-related conditions.
  • You must avoid using other pain-relieving medicine while on treatment with the medicine.

Mode of Action

How Does It Work?

  • Nimesulide blocks a pathway that produces a chemical substance known as prostaglandin that is responsible for the feeling of painful inflammation and other inflammatory reactions.
  • Tizanidine works by slowing some actions in the brain and nervous system which are responsible for muscle tightness, which helps in the relaxation of muscles.

Interactions

Interactions with other medicines

  • Some medicines affect the way Nimesulide+Tizanidine works or Nimesulide+Tizanidine itself reduces the effectiveness of other medicines taken at the same time.
  • Inform the doctor about other medicine, herbal preparation and supplements you are taking to avoid possible interactions.
  • Especially you are taking blood thinner medicines, painkillers, medicine to treat brain-related conditions, blood pressure medicine, immunomodulatory medicines, anti-asthma medicine and anti-diabetic medicine.

Dosage

Overdose

If you think you have taken too much of Nimesulide+Tizanidine contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you missed any dose of Nimesulide+Tizanidine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

No, take Nimesulide+Tizanidine with food to avoid the risk of stomach related problems like a stomach upset.

Nimesulide+Tizanidine does not cause weight gain.

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