Sovihep Bottle Of 28 Tablets
Description
Sovihep tablet is a medicine used to treat chronic hepatitis C in adults and children aged 3 years and older. It contains sofosbuvir as an active ingredient. It works by blocking a protein that the hepatitis C virus needs to replicate and grow, thereby helping to reduce the virus in the body and allowing your immune system to heal the liver. This medicine must be used in combination with other antiviral medicines as prescribed by your doctor. It should be taken once daily, ideally at the same time each day, with or without food. Swallow the tablet whole with a glass of water.
Some people may experience side effects, including headaches, nausea, fatigue, trouble sleeping, irritability, and loss of appetite. Lab tests may also show lower haemoglobin or higher bilirubin levels. If you are diabetic, this medication may lower your blood sugar levels, so monitor your glucose and speak to your doctor about adjusting your diabetes medications if needed.
Certain medications should not be taken with Sovihep tablet, such as modafinil, St. John's wort, rifampicin, phenytoin, carbamazepine, and phenobarbital, as they can reduce its effectiveness. Others, like amiodarone, may cause serious heart issues when combined, so close monitoring is needed. Some medicines may require dose adjustments or extra monitoring, such as ciclosporin, tacrolimus, and warfarin. Be sure to inform your doctor about all the medications you are currently taking.
Pregnant women or those planning pregnancy should avoid using this medicine, especially if taken with ribavirin, as it can harm the unborn baby. Breastfeeding is also not recommended, as it is unclear if the medicine passes into breast milk. Store the tablets in a cool, dry place, away from sunlight, moisture, children, and pets. If you miss a dose, take it as soon as you remember with food, unless it is almost time for the next dose. Never take a double dose to make up for a missed one.
Let your doctor know if you have had hepatitis B in the past, have serious kidney problems or are on dialysis, or recently stopped taking amiodarone. Also, avoid drinking alcohol unless your doctor approves. This medicine is not known to affect your ability to drive. However, if you experience dizziness, tiredness, or blurred vision, avoid driving or operating machinery.
Product Summary
| Offer Price | ₹11161.74 |
| You Save | ₹3524.76 (24% on MRP) |
| Contains | Sofosbuvir(400.0 Mg) |
| Uses | Chronic hepatitis C (CHC) |
| Side effects | Loss of appetite, insomnia, headache, nausea, fatigue |
| Therapy | DRUGS FOR HEPATITIS C |
Uses
Contraindications
- If you are allergic to sofosbuvir or any other ingredients of Sovihep tablet.
- If you are using medicinal products that are strong P-glycoprotein (P-gp) inducers in the intestine, such as carbamazepine, phenobarbital, phenytoin, rifampicin and St. John's wort.
Side effects
- Loss of appetite
- Insomnia
- Headache
- Nausea
- Fatigue
- Irritability
- Decreased haemoglobin levels
- Increased blood bilirubin levels
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You are taking Sovihep tablet without other hepatitis C medicines, as it must be used in combination.
- You have recently stopped taking or have recently stopped taking amiodarone, due to the risk of serious heart problems.
- You have or had hepatitis B, as it may reactivate during treatment.
- You are pregnant or planning pregnancy, especially when using Sovihep tablet with ribavirin.
- You have diabetes, since this medication may lower blood sugar and require medication changes.
- You have severe kidney problems or are on dialysis, as monitoring may be needed.
- You are taking certain other medicines (like modafinil, oxcarbazepine, rifapentine, telaprevir, or boceprevir), which may reduce the effect of this medicine or are not recommended.
Directions for Use
- Sovihep tablet should be taken as directed by your doctor.
- Swallow it whole with a glass of water.
- It should be taken with or after a meal to reduce its side effects.
- It is best to take it at a fixed time for optimal results, and you should not consume it more than prescribed by your doctor.
Storage and disposal
- Store Sovihep tablet in a cool, dry place, protected from direct sunlight, moisture, and heat.
- Keep it out of the reach of children and pets.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Modafinil, St. John's wort, rifampicin, phenobarbital, phenytoin, and carbamazepine should not be used in combination with Sovihep tablet, as they reduce its effectiveness.
- Oxcarbazepine and rifapentine are not recommended with this medication due to the expected reduction in drug levels.
- Amiodarone may cause a serious slow heart rate when taken with this medication; use only if no alternatives and monitor closely.
- Ciclosporin and tacrolimus can be used in combination with sofosbuvir, but may require monitoring and dose adjustments.
- Vitamin K antagonists, such as warfarin, require close INR monitoring during Sovihep tablet treatment.
- Methadone, rifabutin, HIV medications (such as efavirenz, emtricitabine, tenofovir, rilpivirine, darunavir, raltegravir), and oral contraceptives can be taken with Sovihep tablet without dose changes.
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: Can I take Sovihep tablet alone?
Q: Can diabetic patients use Sovihep tablet?
Q: Do I need tests before or during treatment?
References
- Gilead Sciences Ltd. Sovaldi 400 mg film-coated tablets: Summary of Product Characteristics [Internet]. 2023 [cited 2025 Jun 22].
- Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [cited 2025 Jun 22].
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