express delivery
Express delivery to
Select Pincode
Search for Medicine and Healthcare items

Safeguard Sr Strip Of 15 Tablets

15 Tablet(s) in Strip
We do not sell this product
All the Products are packed and stored Safely

Safeguard Sr Strip Of 15 Tablets Description

Safeguard Sr tablet is used as a pain relief medicine for stomach-related conditions. It is also used to reduce pain in persons with osteoarthritis (OA) or rheumatoid arthritis (RA), who are at high

risk of developing medicine-induced gastric and duodenal ulcers. The active ingredients in Safeguard Sr tablet are Misoprostol and Diclofenac. The mode of action of Safeguard Sr tablet is by reducing certain chemical substances in the body while also protecting the stomach from inflammation caused by the pain relievers like diclofenac and other NSAIDs (non-steroidal anti-inflammatory drugs). This medicine protects the surface of the stomach by lowering its acid levels. Directions for use of Safeguard Sr tablets should be strictly followed. This medicine is not meant for pregnant women or those who plan to conceive. Safeguard Sr tablets induce uterine contractions resulting in medical termination of pregnancy, congenital disabilities or premature labour. Nursing mothers should inform their doctor before taking this medicine as it can cause side effects in the baby. Side effects of Safeguard Sr tablets include diarrhoea, shortness of breath, nausea, flatulence, stomach pain, vomiting, constipation, headache, and dizziness.


Product Summary

Offer Price₹158.40
You Save₹21.60 (12% on MRP)
ContainsMisoprostol(200.0 Mg) + Diclofenac(100.0 Mg)
UsesPain in osteoarthritis, Pain in rheumatoid arthritis
Side effectsNausea, Vomiting, Diarrhoea, Stomach cramp, Uterine contractions, Pelvic pain, Menorrhagia (heavy menstrual bleeding), Dehydration
Check more medicines with composition as Misoprostol(200.0 Mg) + Diclofenac(100.0 Mg)

Uses of Safeguard Sr Strip Of 15 Tablets

  • As per USFDA, Safeguard Sr tablets are indicated to treat the signs and symptoms of osteoarthritis (OA) or rheumatoid arthritis (RA) in persons at high risk of developing NSAID-induced gastric and duo...
    Read more

Contraindications of Safeguard Sr Strip Of 15 Tablets

  • Do not take Safeguard Sr tablets or take with caution:
  • If you are pregnant; Safeguard Sr tablet will terminate the pregnancy, especially in the first trimester.
  • If you have serious heart disease or hypertension (high blood pressure)
  • If you have had allergic reactions to any of the components of Safeguard Sr tablets.
  • If you have a history of asthma.
  • If you have autoimmune stomach conditions like Inflammatory Bowel Syndrome (IBS)
  • If you have any infection in the pelvis or sepsis.
  • If you have any bleeding disorder and are currently under treatment for it.
  • If you have an ectopic pregnancy (a pregnancy in which the embryo forms outside the uterus).
  • If you have active bleeding in the digestive system.
  • If you had heart surgery.

Side effects of Safeguard Sr Strip Of 15 Tablets

  • Side effects of Safeguard Sr Tablets include:
  • Diarrhoea
  • Shortness of breath
  • Nausea
  • Flatulence
  • Stomach pain
  • Vomiting
  • Constipation
  • Headache
  • Dizziness

Precautions and Warnings of Safeguard Sr Strip Of 15 Tablets



Can I take the Safeguard Sr tablets during pregnancy?
Safeguard Sr tablet is highly unsafe to use during pregnancy. This medicine can cause the death of a foetus. It may also cause congenital disabilities in the child if the pregnancy is not terminated. It can also cause heavy vaginal bleeding. If you are seeking treatment for ulcers, note that this medicine is contraindicated in pregnancy. Consult your doctor for alternate treatment.

Breast Feeding

Can I take the Safeguard Sr tablets while breastfeeding?
Safeguard Sr tablets can be safe for use by nursing mothers. Limited data on the effects of this medicine on breastfed babies suggest that Safeguard Sr tablets may be safe while breastfeeding as the amount of medicine that enters breast milk is very low. Consult your doctor before using this medicine.


Can I drive if I have taken a Safeguard Sr tablet?
Safeguard Sr tablets can cause side effects like nausea, heavy vaginal bleeding, tiredness, diarrhoea, etc., affecting your ability to drive.


Can I consume alcohol with Safeguard Sr tablets?
Try not to take alcohol until two days after abortion with Safeguard Sr tablets. The exact interactions of this medicine with alcohol are unknown. For gastric ulcers, alcohol may worsen your condition and cause stomach bleeding. It is best to avoid alcohol if you have any stomach problems.

Other General Warnings

Talk to your doctor if
  • You use any herbal products or supplements; some can react with Safeguard Sr tablets.
  • You have high or low blood pressure and are currently under treatment. Monitor your blood pressure levels as Safeguard Sr tablets can cause fluctuations in pressure.
  • You take antacids that contain magnesium; taken with Safeguard Sr tablets can worsen diarrhoea. If you need an antacid, consult your doctor or pharmacist for an alternate medication.

Mode of Action of Safeguard Sr Strip Of 15 Tablets

How Does It Work?

Safeguard Sr Tablets consist of Diclofenac and Misoprostol as their main ingredients. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) medication, which means it works as an anti-analg...
Read more

Directions for Use of Safeguard Sr Strip Of 15 Tablets

  • Take Safeguard Sr tablets exactly as advised by your doctor. Do not exceed the dosage, even if you cannot notice the effects of this medicine.
  • Take Safeguard Sr tablets as a whole with a glass of water. Do not break or chew this tablet.
  • Take this tablet with or after meals to avoid any stomach-related issues.
  • Do not take Safeguard Sr tablets with other medications without informing your doctor.
  • Do not consume this medicine if its packaging is broken.
  • Do not abruptly stop taking Safeguard Sr tablets; this can result in adverse effects from withdrawal.

Interactions of Safeguard Sr Strip Of 15 Tablets

Interactions with other medicines

  • Do not use Safeguard Sr tablets if you have clotting issues or take blood thinners. If Safeguard Sr tablets are prescribed to such a person, they should be closely monitored for any bleeding. Aspirin ...
    Read more
  • Using Safeguard Sr tablets with medicines that lower blood pressure, such as Angiotensin-Converting Enzyme (ACE) inhibitors, Angiotensin Receptor Blockers (ARB), and beta-blockers, can diminish the ef...
    Read more
  • Using antihypertensive medication with Safeguard Sr tablets in older, volume-depleted persons or those with kidney impairment may deteriorate kidney function. Such persons fall in a high-risk category...
    Read more
  • When used together, Safeguard Sr Tablets and diuretics (medicines that remove water and sodium from the body) can reduce sodium in the urine. Affected persons should monitor their blood pressure.
  • Using digoxin with Safeguard Sr tablets can increase serum concentration and prolong the half-life of digoxin in the blood.

Interactions with food items

  • Avoid grapefruit, and its juice as this fruit can interact with the functioning Safeguard Sr tablets.

Storage and disposal of Safeguard Sr Strip Of 15 Tablets

Store Safeguard Sr tablets in dry conditions at room temperature, away from wet surfaces, direct sunlight, and humidity. Dispose of the packaging carefully after use. Check the expiration date before ...
Read more

Dosage of Safeguard Sr Strip Of 15 Tablets


Safeguard Sr tablet overdose can lead to symptoms like sleepiness, tremor, convulsions, shortness of breath, abdominal pain, diarrhoea, fever, palpitations, low blood pressure, and reduced heartbeat. ...
Read more

Missed a Dose

If you have missed a single dose of Safeguard Sr tablet, take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with y...
Read more

Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: For how long can I use Safeguard Sr tablets if I have gastric ulcers?

A: You can use the Safeguard Sr tablets for as long as your doctor recommends. You can continue using this medicine if you are using it as a painkiller for ulcers caused by other medicines like NSAIDs. The treatment can be continued as per your doctor’s recommendation.

Q: Will I have any fertility issues if I take Safeguard Sr tablets?

A: Yes. The diclofenac part of Safeguard Sr tablets can affect fertility. However, it is reversible and does not affect future pregnancies. It does not cause any damage to the uterus either. If you are trying to get pregnant, do not use this medicine. It can cause medical termination of pregnancy if used in the first trimester.

Q: Can I take Safeguard Sr tablets for stomach ulcers if I am not pregnant?

A: If you are a woman of reproductive age, get a pregnancy test to ensure you are not pregnant. Do not use this if you are planning a pregnancy. Both men and women should consult a doctor before taking this medicine.
Product Details
Country of Origin
Expires on or After
Last Updated on: 08 Mar 2022 | 03:11 PM (IST)

Health Articles

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
Our Payment Partners