Rumalef 100mg Tablet
Description
Rumalef Tablet is an anti-rheumatic medicine used in adults to treat active rheumatoid arthritis and active psoriatic arthritis. It helps reduce joint inflammation, swelling, pain, and stiffness, and
can improve movement and physical function over time. In psoriatic arthritis, it also helps control joint symptoms associated with skin lesions. This medicine is usually prescribed for long-term use, as its full benefits may take several weeks to months to become noticeable. Rumalef works by suppressing overactive immune responses that cause inflammation in autoimmune conditions. The active substance interferes with the production of immune cells involved in joint damage, thereby slowing disease progression and reducing symptoms. By controlling immune-mediated inflammation, Rumalef helps protect joints from further damage and improves overall quality of life in patients with chronic inflammatory arthritis. Rumalef Tablet should be taken exactly as advised by your doctor. It can be taken with or without food. Swallow the Tablet whole with a glass of water; do not crush or chew it. Treatment often starts with a higher dose for a short period, followed by a lower daily maintenance dose depending on your condition and response. Regular blood tests and blood pressure checks are required during treatment to monitor liver function, blood cells, and overall safety. Like all medicines, Rumalef may cause side effects, although not everyone gets them. Common side effects include diarrhoea, nausea, abdominal pain, headache, dizziness, hair thinning, skin rash, and mild increases in blood pressure or liver enzymes. Serious allergic skin reactions and liver problems are rare but require immediate medical attention. Contact your doctor promptly if you notice unusual tiredness, persistent fever, breathing problems, yellowing of the skin or eyes, or severe skin reactions.
Product Summary
| Offer Price | ₹87.55 |
| You Save | ₹29.18 (25% on MRP) |
| Contains | Leflunomide(100.0 Mg) |
| Uses | Active rheumatoid arthritis and psoriatic arthritis |
| Side effects | Headache, dizziness, nausea, vomiting |
| Therapy | DRUGS FOR RHEUMATOID ARTHRITIS |
Uses
Contraindications
- If you are allergic to Leflunomide or any other ingredients of Rumalef Tablet.
- If you are suffering from any severe liver or kidney disease.
- If you are pregnant and breastfeeding.
- If you have decreased platelet and white blood cell counts or an bone marrow problem.
- If you have low numbers of proteins in your blood.
- If you are suffering from any disease that affects your immunity system like AIDS.
- If you have any serious infection.
Side effects
- Headache, dizziness
- Nausea, vomiting
- Stomach pain, diarrhea
- Loss of appetite, weight loss
- Tiredness, weakness
- Mouth ulcers
- Skin rashes, dry skin, itching
- Tingling sensation
- increased liver enzymes
Precautions and Warnings
Pregnancy
- Rumalef Tablet must not be used during pregnancy as it may cause some serious birth defects in unborn baby.
- If you are pregnant or think you may be (or if there is any delay in onset of menses), you should consult your doctor immediately.
- When pregnancy is detected, this medicine should be discontinued immediately.
- Proper birth control measures should be taken while consuming it for at least 2 years after the final dose or up to 11 days after the treatment (washout period).
- It is essential to consult your doctor, if you think you are pregnant or are planning to have a baby, before starting treatment with this medicine.
Breast Feeding
Driving
Alcohol
Other General Warnings
- You had any lung diseases like interstitial lung disease
- You have ever had tuberculosis or have been in contact with someone who had the disease.
- You are going to be vaccinated.
- You are breastfeeding.
- You are pregnant, think you may be or are planning to have a baby.
- You are a male patent and want to be father.
- You notice any allergic reaction or unwanted side effects after taking Rumalef Tablet, immediately contact your doctor.
- You should let the doctor, or the laboratory person know that you are using this medicine while going for a lab test, as this medicine may interfere with the lab tests.
- Rumalef Tablet is not recommended for use in patients below the age of 18 years old.
Mode of Action
How Does It Work?
Directions for Use
Interactions
Interactions with other medicines
- Rumalef Tablet may interact with other medications and provide an altered response to the treatment. Please notify your doctor if you are undergoing any other treatments, over-the-counter medications (that you buy without a prescription) and herbal preparations. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled....
- Concomitant use of anticoagulants like warfarin along with this medicine can increase the risk of bleeding.
- Live vaccines can interact with this medicine, thus concomitant use is not recommended.
- Concomitant use of Rumalef Tablet along with Cholestyramine or activated charcoal is not recommended.
- Cyclosporin used in organ transplantation can also be inappropriate to take with this medicine.
- Other medicines like Methotrexate, oral contraceptives, cefaclor, indomethacin, benzylpenicillin, ciprofloxacin, zidovudine, furosemide, rosuvastatin, sulfasalazine should be used with ion along with Rumalef Tablet....
Interactions with food items
Storage and disposal
Dosage
Overdose
Missed a Dose
Content Details
Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What is the use of Rumalef Tablet?
Q: How to take Rumalef Tablet?
Q: Should I take Rumalef Tablet with or without food?
Q: Can Rumalef Tablet be given to children?
References
- Leflunomide Tillomed 20 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2026 [cited 30th Jan 2026]
- Leflunomide Tillomed 20 mg Tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2026 [cited 30th Jan 2026]
- CDSCO. Leflunomide [Internet]. Cdscoonline.gov.in. 2026 [cited 30th Jan 2026]
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