Locid D Capsule
Description
Locid D capsule is used to relieve symptoms related to excess stomach acid and delayed digestion, such as acid reflux, heartburn, nausea, bloating, and indigestion. They are also helpful in managing conditions like gastroesophageal reflux disease (GERD), gastric and duodenal ulcers, and erosive esophagitis. The medicine should be taken before meals, preferably at the same time every day, and swallowed whole with a glass of water.
It contains domperidone and lansoprazole as the active ingredients. Domperidone helps your stomach move food through the digestive system more efficiently by blocking the action of a chemical called dopamine, which can slow down digestion. This action helps relieve nausea, vomiting, and a sense of fullness or bloating. Lansoprazole works by reducing the amount of acid your stomach produces, giving relief from acid-related discomfort and allowing the stomach and oesophagus to heal.
Some side effects that may occur include headache, dizziness, stomach pain, nausea, diarrhoea, constipation, dry mouth, and gas. These effects are generally mild but should be discussed with a doctor if they persist or worsen. In rare cases, serious reactions like heart rhythm disturbances, especially in older adults or those with heart issues, can occur with domperidone.
This medicine may interact with other medications such as HIV drugs, antifungals, certain antibiotics, and drugs affecting heart rhythm or blood clotting. Antacids and sucralfate can interfere with the absorption of lansoprazole, so they should be taken at different times. Always inform your doctor of all the medicines, supplements, or herbal remedies you are taking to avoid harmful interactions.
Pregnant women should only take this medicine if their doctor considers it necessary. Breastfeeding is not recommended during use. Dizziness or drowsiness may occur; therefore, exercise caution when driving or operating machinery. Long-term use may require monitoring of magnesium, vitamin B12, or bone health, especially in older adults. Regular follow-ups are important to ensure continued safety and effectiveness.
Product Summary
| Offer Price | ₹80.60 |
| You Save | ₹25.45 (24% on MRP) |
| Contains | Domperidone(10.0 Mg)+Lansoprazole(30.0 Mg) |
| Uses | Gastro-oesophageal reflux disease(GERD) |
| Side effects | Headache, dizziness, nausea, diarrhoea, stomach ache, constipation |
| Therapy | ANTACID AND ANTI-EMETIC |
Uses
- Gastro-esophageal reflux disease(GERD)
- Erosive esophagitis
- Gastric and duodenal ulcers
- The relief of the symptoms of nausea and vomiting, epigastric sense of fullness, upper abdominal discomfort and regurgitation of gastric contents.
Contraindications
- If you are allergic to domperidone, lansoprazole or any other ingredients of Locid D capsule.
- If you have a type of brain tumour called a prolactinoma, which affects hormone levels.
- If you have any condition where moving your stomach contents faster could be harmful, such as bleeding in the stomach or intestines, a blockage, or a hole in the gut.
- If you have serious liver or kidney problems.
- If you are taking a medicine called atazanavir (used for HIV treatment), it should not be combined with lansoprazole.
Side effects
- Headache
- Dizziness
- Nausea
- Diarrhoea
- Stomach ache
- Constipation
- Vomiting
- Flatulence
- Dry mouth or throat
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have ongoing stomach ulcers, liver issues, or need long-term treatment, as lansoprazole can hide serious conditions and needs careful monitoring.
- You take HIV medicines, antibiotics like ketoconazole, or other drugs that interact with lansoprazole or domperidone, as effectiveness or side effects may be affected.
- You have a vitamin B12 deficiency, low magnesium, weak bones, or a history of fractures, as these may worsen with long-term use of PPIs like lansoprazole.
- You have persistent diarrhoea, skin rashes, or digestive infections, as these could be rare but serious side effects that need medical attention.
- You have heart conditions, are over 60 years of age, or take medicines that affect heart rhythm, since domperidone may increase the risk of serious heart problems.
Directions for Use
- Locid D capsule should be taken as directed by your doctor.
- Swallow it whole with a glass of water.
- It should be taken before a meal.
- It is best to take it at a fixed time for optimal results, and you should not consume it more than prescribed by your doctor.
Storage and disposal
- Store Locid D capsule in a cool, dry place, protected from direct sunlight, moisture, and heat.
- Keep it out of the reach of children and pets.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
- Domperidone works by helping food move more smoothly through your stomach and intestines. It does this by blocking a chemical in your body called dopamine, which slows down digestion. By speeding up the movement of food through your digestive system, domperidone can help relieve symptoms such as nausea, vomiting, bloating, and a feeling of fullness. It may also help prevent stomach contents from flowing back into the food pipe, which can reduce heartburn and discomfort....
- Lansoprazole works by reducing the amount of acid your stomach makes. It does this by blocking tiny pumps in the stomach lining that produce acid. By lowering acid levels, lansoprazole helps relieve symptoms such as heartburn, acid reflux, and stomach ulcers, allowing the stomach and food pipe to heal. It provides long-lasting relief from excess stomach acid and is usually taken before meals for best results....
Interactions
Interactions with other medicines
- Lansoprazole may reduce the effectiveness of certain medicines like HIV drugs (atazanavir), antifungals (ketoconazole), and birth control pills.
- It can increase the effects or side effects of medications such as digoxin, tacrolimus, methotrexate, and warfarin, which may require monitoring.
- Medicines like fluvoxamine can increase lansoprazole levels, while rifampicin and St. John’s Wort can reduce its effect.
- Antacids and sucralfate may interfere with the absorption of lansoprazole and should be taken at a different time.
- Always share a complete list of your medications with your doctor to avoid potentially harmful interactions.
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: Are there any food restrictions?
Q: Can children take this medicine?
References
- Electronic Medicines Compendium (emc). Lansoprazole 30 mg gastro-resistant capsules, hard – Summary of Product Characteristics (SmPC) [Internet]. London, UK: emc; [cited 2025 Jun 27].
- NAFDAC. [Product Name] — Summary of Product Characteristics [Internet]. Nigeria; 2024 Nov 18 [cited 2025 Jun 27].
- Central Drugs Standard Control Organisation. Drugs. [Internet]. New Delhi: Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India; [cited 2025 Jun 27].
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