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Alprax Plus Tablet

10 Tablet(s) in Strip
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Alprax Plus Tablet Description

Alprax Plus is a prescription medication. It is primarily used in the management of anxiety and panic disorders. It is a combination of two medications, Sertraline and Alprazolam. Alprazolam is a ben

zodiazepine that produces calming, sedative effects on the brain, whereas Sertraline regulates the chemical messenger Serotonin. Anxiety is a condition characterised by nervousness or restlessness. This can be associated with a feeling of impending doom, increased heart rate, sweating, trembling, and rapid breathing. Panic disorder is a type of anxiety-disorder with a sense of loss of control and fear.


Product Summary

Offer Price₹61.42
You Save₹8.38 (12% on MRP)
ContainsSertraline(25.0 Mg) + Alprazolam(0.5 Mg)
UsesTo treat anxiety and panic disorders
Side effectsDrowsiness, tiredness, weight loss/gain, nausea, vomiting, diarrhoea, constipation, dizziness, poor balance, difficulty in concentrating, slurring of speech, loss of libido, potential to develop dependence, increased misuse/abuse potential.
Check more medicines with composition as Sertraline(25.0 Mg) + Alprazolam(0.5 Mg)

Uses of Alprax Plus Tablet

  • Anxiety Disorder
  • Panic Disorder

Contraindications of Alprax Plus Tablet

  • If you are a patient with acute narrow-angle glaucoma.
  • If you are hypersensitive to either of the medications in this fixed-dose combination.
  • If you have any history of substance abuse.
  • If you have liver and kidney disease.
  • Sertraline is contraindicated with disulfiram only in solution form; it may cause an alcohol-disulfiram reaction.
  • There is a US black box warning for use in children and young adults.

Side effects of Alprax Plus Tablet

  • Drowsiness
  • Tiredness
  • Diarrhoea or Constipation
  • Increased sweating
  • Headache
  • Nausea, Vomiting

Precautions and Warnings of Alprax Plus Tablet



Can I take Alprax Plus during pregnancy?
This medication is considered unsafe in pregnancy. It is a category c medication. Inform your doctor about your pregnancy or intention to conceive at the time of prescription.

Breast Feeding

Can I take Alprax Plus while breastfeeding?
This medicine is considered unsafe during breastfeeding. Discuss with your doctor for more information.


Can I drive if I have taken Alprax Plus?
Driving and operating other heavy machinery while on this medicine is not recommended as it may cause light-headedness, sedation and sleepiness.


Can I consume alcohol with Alprax Plus?
The mixing of alcohol with Alprazolam can cause life-threatening side effects on the user, leading to respiratory depression, coma and even death. It is strictly contraindicated.

Other General Warnings

Talk to your doctor if
  • You have a history of addiction or substance misuse.
  • You are taking any other medications. The ingredients of this tablet may react with several other tablets that use the same pathway of metabolism in the body.

Mode of Action of Alprax Plus Tablet

How Does It Work?

Alprazolam belongs to a class of medicines called Benzodiazepines. These medicines primarily act on the brain pathways to increase the action of a chemical messenger, otherwise known as a neurotransmi...
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Directions for Use of Alprax Plus Tablet

  • This medication should be taken as prescribed by the treating physician.
  • It is recommended to take this medication on a regular schedule at the same time every day for best results.
  • Swallow this medication as a whole. Don’t crush, chew or break the Alprax Plus tablet.
  • It’s recommended to finish the full course of this medication as prescribed by your doctor.
  • Abrupt stoppage of the medicine can cause withdrawal side effects. Consult your doctor before stopping this medication.
  • This medication has a habit-forming tendency; hence it is recommended to follow the directions of your treating physician precisely and have a regular follow-up.

Interactions of Alprax Plus Tablet

Interactions with other medicines

  • Concomitant use of this medication with opioids and other CNS depressants is contraindicated, as it may cause respiratory depression, coma and death.
  • Alprax Plus should not be mixed with medications that cause the arrest of bleeding, such as aspirin, NSAIDs, heparin, warfarin, and other anti-coagulants as sertraline in itself causes decreased activ...
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  • This medicine should not be used concomitantly or within two weeks of using Monoamine oxidase inhibitors (MAOIs) like Selegiline, Rasagiline, etc. It is potentially life-threatening.
  • Patients who are taking other medications that increase serotonin levels should receive education regarding the risks.

Interactions with food items

  • This medication does not interact with food items.
  • It is known to cause both weight loss and weight gain; hence adjusting your dietary practices and exercising regularly while on this medication are beneficial.

Storage and disposal of Alprax Plus Tablet

Store in a cool and dry place away from direct light and moisture. Do not use the medicine after the date of expiration. Keep Alprax Plus tablets away from children and pets. Do not flush the medicati...
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Dosage of Alprax Plus Tablet


Symptoms of overdose may include fainting, somnolence, impairment of motor functions – dizziness, poor coordination, muscle weakness, loss of balance, low blood pressure (hypotension), shallow breathi...
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Missed a Dose

If you miss a dose of this tablet, it is advised to take it as soon as possible. If the duration missed is too long, and it is almost time for the next dose, it’s recommended to skip the missed dose a...
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Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: Can I have an occasional drink while I’m on this medication?

A: No, even occasional alcohol intake while on Alprax Plus is strongly inadvisable as it can result in potentially life-threatening side effects such as respiratory depression, coma and death.

Q: I feel drowsy while I am on this medication. Can I stop taking it?

A: Abrupt stoppage of this medication can cause withdrawal symptoms which can be severe and debilitating. Consult your doctor for solutions and a safe manner to stop this medication if required.

Q: I use this medicine regularly, but I still feel anxious. Can I increase the frequency of this medication?

A: This medication has habit forming tendencies. Do not increase the dose or frequency of this medication unless prescribed by your doctor. Regular follow-up while on this medication is essential.
Product Details
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Last Updated on: 25 Feb 2022 | 10:20 AM (IST)

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