Topiramate

Molecule Description

Topiramate is a prescription medicine used to treat seizures (epilepsy) and pre

vent migraines. It belongs to a class of medications called ‘carbonic anhydrase inhibitors.’

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Topiramate

To treat epilepsy - as a single medicine in people aged over six years
To treat epilepsy – in combination with other medicines in people aged over two years
To prevent migraine headaches in adults

Contraindications of Topiramate

When should one not use Topiramate

If you are allergic to the medicine or any other substances used in the medicine
To prevent migraine attacks in women of childbearing potential, if not using birth control methods

Side effects of Topiramate

Common side effects of this drug are:

New onset or worsening of existing depression (most common)
Seizures (fits)
Mood changes – anxiety, getting irritated quickly or disoriented
Difficulty to concentrate, think and memory problems
Kidney stones, painful urination
Confusion
Metabolic acidosis
Increased acid levels in blood (troubled breathing, irregular heartbeats, etc.)
Absent or decreased sweating
Suicidal tendencies
Vision problems
Glaucoma (rare)

Precautions and Warnings of Topiramate

Pregnancy

Can I take Topiramate during pregnancy?

Consult your doctor if you are pregnant or planning a pregnancy before taking Topiramate. Topiramate is known to have the potential to cause defects in unborn babies (teratogenic) and should not be given in pregnancy. If it is necessary and no alternatives exist, strict supervision is recommended at your own risk.

Breast Feeding

Can I take Topiramate while breastfeeding?

Topiramate is not recommended in breastfeeding women as significant levels of the medicine are secreted in breast milk.

Driving

Can I drive if I have consumed Topiramate?

As Topiramate acts on the brain, it is expected to cause drowsiness, dizziness and vision problems. It is advisable not to drive in the first few months after starting the medicine and later on, do not drive for longer durations.

Alcohol

Can I consume alcohol with Topiramate?

Avoid alcohol while on medication of Topiramate as it may intensify drowsiness.

Other General Warnings

Talk to your doctor if

You have kidney-related problems (kidney stones)
You have a history of acidosis (high levels of acids or electrolytes in blood)
You have a growth problem
You have a high-fat diet
You have liver or eye problems
You have any problems in concentration, memory or thinking

Mode of Action of Topiramate

How Does It Work?

Seizures occur due to decreased levels of a substance called GABA (Gamma Amino Butyric acid), which regulates signals and messages in the brain. Topiramate acts by specific mechanisms and increases th...

Interactions of Topiramate

Interactions with other medicines

Medicines used to treat diabetes (Pioglitazone, Metformin, Glibenclamide)
Medicines used to treat depression or anxiety (Venlafaxine, Flunarazine, Amitriptyline)
Medicines used to treat heart disease or blood pressure (Propranolol, Diltiazem, Hydrochlorothiazide)
Medicines used to treat psychiatric problems (Risperidone, Lithium)
Other anti-seizure medications

Interactions with food items

Topiramate does not interact with food. It can be taken before or after meals.

Dietary Restrictions of Topiramate

No information is available on dietary restrictions while you are taking Topiramate, consult your doctor or pharmacist for further information.

Dosage of Topiramate

Overdose

If you suspect an overdose of Topiramate, contact doctor immediately; symptoms may include feeling sleepy, tired, less alert or have blurred vision. You may require hospital admission and are advised ...

Missed a Dose

Take the missed dose as early as you remember it. However, if it is less than 6 hours before you are scheduled to take your next dose, skip the missed dose and continue your regular dosing schedule. D...

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: How long does it take for Topiramate to act? Will I get instant relief?

A: Topiramate takes time to act. In case of seizures, it will take about two weeks and up to 3 months if you are taking it to prevent migraines.

Q: I am not having any seizures or migraines. Can I stop the medication of Topiramate?

Topiramate is a safe medicine if you take it as per schedule and can be taken for long periods of time
If you want to stop taking this medicine, you should consult your doctor
If you are taking this medicine to treat seizures, do not stop it suddenly as it will cause withdrawal symptoms and the dose needs to be tapered down gradually

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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