Sitagliptin is an antidiabetic medicine that can inhibit an enzyme called DPP4 which is necessary for the metabolism of glucose and insulin....
Precautions and Warnings
Mode of Action
Uses of Sitagliptin
Type 2 diabetes mellitus
Contraindications of Sitagliptin
When should one not use Sitagliptin
Do not take Sitagliptin if you have-
Type I diabetes mellitus
Allergic reaction to Sitagliptin
Any severe infection
Side effects of Sitagliptin
Common side effects of this drug are:
Stuffed or runny nose
Pancreatitis (severe stomach pain, nausea, vomiting) (serious side effect)
Swelling of hands or legs
Precautions and Warnings of Sitagliptin
Can I take Sitagliptin during pregnancy?
You should not take this medicine during pregnancy. Limited information is available about its safety in pregnancy, hence do not take this medicine unless it is considered essential by a physician.
Can I take Sitagliptin while breastfeeding?
It is unknown if Sitagliptin passes into breast milk. You should not take this medicine if you are breastfeeding or plan to breastfeed without your doctor advise.
Can I drive if I have consumed Sitagliptin?
Sitagliptin is not known to have an impact on driving ability; however, dizziness and drowsiness is reported in some people
Also, Sitagliptin in combination with other diabetes medicines can cause low blood glucose, which may affect your ability to drive
Keep a juice or a chocolate bar in the car close to you when driving. In case you start feeling any of the above symptoms of hypoglycemia, immediately drink the juice or eat the chocolate bar
Can I consume alcohol with Sitagliptin?
It is unsafe to consume alcohol with this medicine. Consumption of alcohol, together with this drug, may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on the quantity and frequency of alcohol consumption. Also, alcohol can increase the risk of developing the severe side effect of pancreatitis.
Other General Warnings
Talk to your doctor if
An allergic reaction to Sitagliptin
Pancreatitis (swelling of pancreas)
Rapid weight loss
Alcoholism or very high levels of triglycerides (a form of fat) in your blood
Type 1 diabetes mellitus
Mode of Action of Sitagliptin
How Does It Work?
Sitagliptin is used to lower blood sugar levels in patients with Type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin usually). It increases insulin synthesis by the pancreas, thereby reducing glucose levels. It also decreases glucagon levels, which is a counter-hormone of insulin, thus further reducing blood sugar levels....
Interactions of Sitagliptin
Interactions with other medicines
There can be an increased risk of fall in sugar levels when used in combination with Sulfonylureas (Glimepiride) or insulin. Ensure you talk to your doctor about any other drugs you might be taking.
Dietary Restrictions of Sitagliptin
Sitagliptin can help lower your blood sugar levels when combined with lifestyle changes such as improved diet, exercise and avoiding smoking. Follow the nutrition plan that your doctor, registered dietitian or diabetes educator recommends. It is advisable to follow a strict diabetic diet and exercise regimen to further improve overall control of the disease....
Dosage of Sitagliptin
You may experience slow, fast or irregular heartbeats, fainting, difficulty in breathing, dizziness, confusion, increased sweating and tremors due to sudden decrease in the blood sugar levels. Immediately consume some sugar/ glucose drink or eat a chocolate and call for emergency medical help....
Missed a Dose
If you missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compensate for a missed one. Taking double doses can be harmful as it can drop the glucose level strictly....
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.