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molecule

Sitagliptin

Molecule Description

Sitagliptin is an antidiabetic medicine that can inhibit an enzyme called DPP4 w...
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    Uses
    Contraindications
    Side effects
    Precautions and Warnings
    Mode of Action
    Interactions
    Dietary Restrictions
    Dosage
    References
uses

Uses of Sitagliptin

Type 2 diabetes mellitus
contraindications

Contraindications of Sitagliptin

When should one not use Sitagliptin

  • Do not take Sitagliptin if you have-
  • Type I diabetes mellitus
  • Allergic reaction to Sitagliptin
  • Any severe infection
  • Diabetic coma
sideEffects

Side effects of Sitagliptin

Common side effects of this drug are:

  • Stuffed or runny nose
  • Sore throat
  • Headache
  • Dizziness
  • Nausea, vomiting
  • Joint pain
  • Pancreatitis (severe stomach pain, nausea, vomiting) (serious side effect)
  • Constipation
  • Itching, rash
  • Swelling of hands or legs
precautionsAndWarnings

Precautions and Warnings of Sitagliptin

pregnancy

Pregnancy

Q:
Can I take Sitagliptin during pregnancy?
A:
You should not take this medicine during pregnancy. Limited information is available about its safety in pregnancy, hence do not take this medicine unless it is considered essential by a physician.
breastfeeding

Breast Feeding

Q:
Can I take Sitagliptin while breastfeeding?
A:
It is unknown if Sitagliptin passes into breast milk. You should not take this medicine if you are breastfeeding or plan to breastfeed without your doctor advise.
driving

Driving

Q:
Can I drive if I have consumed Sitagliptin?
A:
  • Sitagliptin is not known to have an impact on driving ability; however, dizziness and drowsiness is reported in some people
  • Also, Sitagliptin in combination with other diabetes medicines can cause low blood glucose, which may affect your ability to drive
  • Keep a juice or a chocolate bar in the car close to you when driving. In case you start feeling any of the above symptoms of hypoglycemia, immediately drink the juice or eat the chocolate bar
alcohol

Alcohol

Q:
Can I consume alcohol with Sitagliptin?
A:
It is unsafe to consume alcohol with this medicine. Consumption of alcohol, together with this drug, may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on the quantity and frequency of alcohol consumption. Also, alcohol can increase the risk of developing the severe side effect of pancreatitis.
otherGeneralWarnings

Other General Warnings

Talk to your doctor if
  • An allergic reaction to Sitagliptin
  • Kidney disease
  • Gallstones
  • Pancreatitis (swelling of pancreas)
  • Rapid weight loss
  • Alcoholism or very high levels of triglycerides (a form of fat) in your blood
  • Type 1 diabetes mellitus
modeOfAction

Mode of Action of Sitagliptin

How Does It Work?

Sitagliptin is used to lower blood sugar levels in patients with Type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin usually). It increases ins...
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interactions

Interactions of Sitagliptin

Interactions with other medicines

There can be an increased risk of fall in sugar levels when used in combination with Sulfonylureas (Glimepiride) or insulin. Ensure you talk to your doctor about any other drugs you might be taking.
dietaryRestrictions

Dietary Restrictions of Sitagliptin

Sitagliptin can help lower your blood sugar levels when combined with lifestyle changes such as improved diet, exercise and avoiding smoking. Follow the nutrition plan that your doctor, registered die...
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dosage

Dosage of Sitagliptin

Overdose

You may experience slow, fast or irregular heartbeats, fainting, difficulty in breathing, dizziness, confusion, increased sweating and tremors due to sudden decrease in the blood sugar levels. Immedia...
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Missed a Dose

If you missed any dose, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compe...
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Content Details

WRITTEN BY
REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
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