Rivaroxaban

Molecule Description

Rivaroxaban is a blood thinner that prevents the formation of blood clots.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Rivaroxaban

This medicine is used to prevent the formation of blood clots due to a specific irregular heartbeat pattern, called atrial fibrillation or after hip or knee replacement surgery
It is also used to treat blood clots, such as in Pulmonary Embolus (PE) or Deep Vein Thrombosis (DVT)

Contraindications of Rivaroxaban

When should one not use Rivaroxaban

You are allergic to Rivaroxaban
You have a stomach ulcer
You have injury or bleeding in the brain or recent surgery of the brain or eyes
You have a liver disease which may cause an increased risk of bleeding

Side effects of Rivaroxaban

Common side effects of this drug are:

Anemia
Bleeding (gum bleeds, nose bleeds, black or tarry stool, blood in cough and vomit, increased menstrual bleeding, bleeding from an operation site)
Swelling or pain in the limbs
Stomach pain
Diarrhea, constipation
Decreased in blood pressure (dizziness or fainting on standing)
Decreased in platelets
Fainting
Dry mouth
Allergic reaction

Precautions and Warnings of Rivaroxaban

Pregnancy

Can I take Rivaroxaban during pregnancy?

Do not take Rivaroxaban if you are pregnant. If you are a woman of childbearing age, use effective contraception.

Breast Feeding

Can I take Rivaroxaban while breastfeeding?

Do not take this medicine if you are breastfeeding. Only limited information is available for this medicine to use during breastfeeding.

Driving

Can I drive if I have consumed Rivaroxaban?

Caution is advised as it may cause dizziness.

Alcohol

Can I consume alcohol with Rivaroxaban?

No known interaction.

Other General Warnings

Talk to your doctor if

You have kidney problems
Active bleeding or bleeding disorder
You have a history of gastric ulcer
You are taking other blood thinners like Warfarin, Heparin
You have had a recent stroke
You have high uncontrolled blood pressure
Problems in the eye (retinopathy)
Do not stop this medicine as your own as this can cause an increased risk of blood clots
If you are on this medicine and have a surgery coming up immediately inform your doctor

Mode of Action of Rivaroxaban

How Does It Work?

This medicine acts as a blood thinner. It stops the existing blood clots from increasing in size and also prevents the formation of new lumps in the blood.

Interactions of Rivaroxaban

Interactions with other medicines

Aspirin
Anticoagulant like Warfarin (increased bleeding)
Antifungal like Fluconazole, Ketoconazole
Thrombolytics
Clarithromycin
Erythromycin
Verapamil
Antiplatelet
Defibrotide

Interactions with food items

This medicine has interactions with grapefruit juice. Avoid the consumption of grapefruit juice while taking this medicine.

Dietary Restrictions of Rivaroxaban

No information is available on dietary restrictions while you are taking Rivaroxaban, consult your doctor or pharmacist for further information.

Dosage of Rivaroxaban

Overdose

Overdose symptoms may cause excessive bleeding through any of the external orifices or internal bleeding in vital organs. This bleeding can be fatal. Seek emergency medical attention if you think you ...

Missed a Dose

If you missed any dose, take it as soon as you remember. If the time for next dose is close, skip the missed dose & do not take an extra dose of medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking this medicine?

A: Discuss the risks and benefits of using this medicine. You should not use this medicine if you are allergic to it or if you have active or uncontrolled bleeding. Give a detailed account of your medical and surgical history, especially if you have kidney or liver disease. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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