Prednisolone Acetate

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Molecule Description

Prednisolone Acetate belongs to the group of steroidal anti-inflammatory medicines. It is used as eye drops in adults for the short-term treatment of eye inflammation.

Uses

Inflammatory condition of eyes (redness, swelling and watering).

Contraindications

When should one not use Prednisolone Acetate

Viral infection of eyes
Epithelial herpes simplex keratitis (dendritic keratitis)
Vaccinia and varicella infections of the eye
Fungal infections involving eyes
Mycobacterial diseases, including tuberculosis
Any acute, untreated eye infection with pus formation
Glaucoma (raised pressure inside the eyes)
Patients with uncontrolled diabetes

Side effects

Common side effects of this drug are:

Elevated IOP (pressure inside the eyes)
Transient stinging or burning of eyes
Blurred vision (temporary)
Irritation in eyes
Severe allergic reactions (rash, difficulty breathing, tightness in the chest)
Swelling of the mouth, face, lips, or tongue
Changes in vision
Discharge from eyes
Secondary infection of eyes on prolonged use

Precautions and Warnings

Pregnancy

Consult your doctor before taking this medicine as steroids may be harmful for the baby.

Breast Feeding

It is unknown if this medicine is secreted into breast milk. Women should consult with the doctor once during nursing.

Driving

It may cause temporary blurred vision, so the patient should be cautious while driving.

Alcohol

It is better to avoid drinking alcohol.

Other General Warnings

Talk to your doctor if

Do not instill this medicine when using contact lenses
Do not touch the tip of the nozzle
Wash your hands before instilling the eye drops
Do not overuse this medicine or take for longer than prescribed duration
Tell your doctor if you have viral, bacterial or fungal infection of eyes
Glaucoma (raised pressure inside the eyes)
Uncontrolled diabetes
You are taking medicines for HIV

Mode of Action

How Does It Work?

Prednisolone Acetate controls the inflammatory response by suppressing certain chemical mediators responsible for it. This prevents the flare-up of the disease conditions.

Interactions

Interactions with other medicines

Antifungals
High blood pressure medicines, such as diuretics (water tablets)
Carbenoxolone (used to treat stomach ulcers)
Medicines used to treat myasthenia gravis
Medicines for epilepsy such as Carbamazepine, Phenobarbitone, Phenytoin
Aminoglutethimide (used to treat some breast cancers)
Oral contraceptives
Somatropin (used to treat growth problems)
Diabetic medicines such as Insulin, Glibenclamide or Metformin
Blood thinners - Warfarin
Rifampicin

Interactions with food items

The patient should avoid high sodium seasoning mixes, processed, canned and preserved foods, extra salt at the table, low or non-fat dairy products, fresh, lean meat, seafood, and poultry.

Dosage

Overdose

Overdose symptoms of ophthalmic drops of Prednisolone Acetate have not been reported. But, if you see any unusual signs in or around the eyes, consult your doctor immediately.

Missed a Dose

If you miss a dosage, use the drop as soon as you remember. If you are close to the next scheduled dose, then skip the missed dose. Do not instill the eye drop twice.

Frequently Asked Questions (FAQs)

You must inform your doctor if you are suffering from any ailments, taking any medication, or using contact lenses. Prednisolone Acetate may interact with the medicine or affect the disease that you may be experiencingIf you have diabetes, heart problem, liver, kidney, stomach, and intestinal disorders, depression, seizures, thyroid problems, etc.If you suffer from any infection like HIV, tuberculosis, fungal, bacterial or viral

You must avoid touching your eyes repeatedly, as this makes you prone to infections. Maintain good overall hygiene.

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