Metoprolol Succinate+Amlodipine

Uses	High blood pressure and angina pectoris
Therapy	Anti-Hypertensive
Side Effects	Dizziness, sleepiness, headache, nausea

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Molecule Description

Metoprolol Succinate+Amlodipine is a medicine used to treat high blood pressure and angina, which is chest pain caused by reduced blood flow to the heart. It contains a combination of two active ingredients, amlodipine and metoprolol, that work together to relax blood vessels, improve blood flow, and lower blood pressure. This dual action helps reduce the risk of heart attacks, strokes, and other heart-related complications. Amlodipine works by widening and relaxing blood vessels, making it easier for blood to flow through the body. Metoprolol slows down the heart rate, reducing the heart's workload and oxygen demand. Together, these actions help control blood pressure, relieve chest pain, and improve heart function. You should take Metoprolol Succinate+Amlodipine exactly as prescribed by your doctor. Taking it at a fixed time each day ensures consistent blood pressure control and optimal effectiveness. Do not skip doses or take more than recommended, as this can affect treatment results and increase the risk of complications. High blood pressure and heart diseases are serious conditions that can affect other organs such as the brain, kidneys, and blood vessels if left untreated. Inform your doctor about your complete medical history, including any liver, kidney, or heart problems, before starting this medicine. Also, disclose all other medications or supplements you are taking to avoid interactions. Along with taking Metoprolol Succinate+Amlodipine, lifestyle modifications are important for optimal results. Maintain a heart-healthy diet, exercise regularly, limit salt intake, avoid smoking, and manage stress. Regular monitoring of blood pressure and follow-ups with your doctor will help you achieve better control over your heart health and blood pressure.

Uses

Metoprolol Succinate+Amlodipine is used for the treatment of high blood pressure, angina pectoris (radiating chest pain due to reduced blood flow to the heart) and coronary artery disease.

Contraindications

When should one not use Metoprolol Succinate+Amlodipine

If you are allergic to any of the ingredients of this medicine.
If you have any heart-related conditions such as heart failure problem, irregular heartbeats and heart blockage.
If you have a blood circulation problem which affects the blood supply to different body parts.
If you have a hormone-secreting tumour in the adrenal gland (Pheochromocytoma).
If you are suffering from metabolic acidosis, a condition when the body produces excess acid.

Side effects

Common side effects of this drug are:

Headache
Dizziness
Nausea
Stomach pain
Sleepiness
Tiredness
Ankle swelling
Swelling

Precautions and Warnings

Pregnancy

This medicine is not safe to be taken during pregnancy. If pregnancy is detected while taking this medicine inform your doctor immediately.

Breast Feeding

You should not take this medicine while breastfeeding. Consult your doctor for more information.

Driving

You should be cautious while driving if you are taking this medicine, especially right after initiation of the treatment. You may feel dizzy and sleepy after taking this medicine. Therefore, it would be better to avoid driving.

Alcohol

Avoid consuming alcohol when you are taking this medicine as it is known to cause low blood pressure when taken with this medicine.

Other General Warnings

Talk to your doctor if

You have any health conditions related to the heart, liver and kidneys.
You experience that there is no improvement in blood pressure and it is getting worse.
You are suffering from high or low blood sugar level or develop thyroid-related disorders.
You are suffering from asthma or obstruction of the airways.
You have a planned surgery or operation.
You are above 60 years, pregnant or are breastfeeding.

Mode of Action

How Does It Work?

Metoprolol Succinate+Amlodipine works by the combined action of metoprolol & amlodipine. Metoprolol works by blocking beta receptors in the heart, which slows down the heart rate and reduces the workload of the heart. This leads to a decrease in blood pressure and relieves chest pain due to angina.
Amlodipine works by relaxing blood vessels and reducing the load on the heart. It also improves blood circulation in heart muscles and controls chest pain due to angina.

Interactions

Interactions with other medicines

Metoprolol Succinate+Amlodipine can affect the action of other medicines or other medicines can alter the action of Metoprolol Succinate+Amlodipine if taken at the same time.
Tell your doctor about all the medicines, herbals and supplements you are currently taking or might take to avoid any possible interactions.
You may experience an excess drop in blood pressure if you are taking any other blood pressure-lowering medicine, antifungal medicines and antibiotics with this medicine.
Medicines that are used for irregular heartbeats if taken along with this medicine can lead to a drop in blood pressure and slow heartbeats.
Other medicines such as immunomodulators, muscle relaxants, pain killers, cholesterol-lowering medicines should be used cautiously.

Interactions with food items

Grapefruit, apple & orange juice should be avoided for at least for 4 hours after taking this medicine.

Dosage

Overdose

Symptoms of an overdose of this medicine include laziness, wheezing, uneven heart rhythm, slow heartbeats, low blood pressure, constriction of airways and drop in blood sugar levels. Seek immediate medical help in case of an overdose.

Missed a Dose

Do not take a double dose of this medicine if you have missed a dose; take the next dose as soon as you remember. It would be best if you never miss a dose of blood pressure medicine as it can lead to serious side effects like sudden fall in blood pressure and associated symptoms such as fainting, lightheadedness, dizziness, dehydration, etc.

Frequently Asked Questions (FAQs)

The most common side effects of this medicine are sleepiness, dizziness, headache, stomach pain, nausea, swelling in the ankle and fatigue.

This medicine is used for the treatment of high blood pressure and chest pain due to reduced blood flow to the heart (angina).

No, you should never stop taking this medicine on your own without talking to your doctor even if you are feeling well. Abruptly stopping this medicine may cause chest pain, heart attack or irregular heartbeats. Your doctor will probably decrease your dose gradually if required.

You should take your medicine regularly at the same time. In addition to that, making lifestyle changes will also help to control your blood pressure. These changes include eating a healthy diet, low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes every day and reducing alcohol consumption and avoiding smoking.