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Mefenamic Acid

Molecule Description

Mefenamic Acid is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It is used fo

r treating mild to moderate pain.


Uses of Mefenamic Acid

  • Post-operative and post-partum pain
  • Painful menstrual periods
  • Joint pain
  • Dental pain
  • Headache

Contraindications of Mefenamic Acid

When should one not use Mefenamic Acid

Do not take if you are allergic to Mefenamic Acid or any ingredient of this medicine.

Side effects of Mefenamic Acid

Common side effects of this drug are:

  • Nausea and vomiting
  • Stomach ache
  • Bleeding in stomach/ ulcer
  • Ringing in the ears
  • Rise in blood pressure
  • Constipation
  • Itching and rash
  • Breathlessness
  • Kidney disorder - swelling of legs and decreased urination
  • Liver disorder – nausea, stomach pain, jaundice (yellowing of the skin or eyes), dark colored urine, loss of appetite, etc.
  • Heart disease - swelling of feet, unusual tiredness, unusual weight gain

Precautions and Warnings of Mefenamic Acid



Can I take Mefenamic Acid during pregnancy?
You should not take this medicine during pregnancy.

Breast Feeding

Can I take Mefenamic Acid while breastfeeding?
It is probably unsafe to take this medicine while breastfeeding. Trace amounts of this medicine may be present in breast milk and may be transmitted to the baby.


Can I drive if I have consumed Mefenamic Acid?
Drive only if you feel stable and alert after taking this medicine.


Can I consume alcohol with Mefenamic Acid?
It is unsafe to consume alcohol with this medicine as it increases the risk of bleeding from the stomach.

Other General Warnings

Talk to your doctor if
  • If you have high cholesterol
  • If you have liver, kidney or heart disease
  • If you have any heart-related problems
  • If you have diabetes
  • If you have asthma
  • If you have a history of epilepsy
  • If you have galactose intolerance
  • If you have recovery time immediately after coronary bypass surgery
  • High blood pressure

Mode of Action of Mefenamic Acid

How Does It Work?

This medicine inhibits the release of specific chemical mediators that are responsible to cause pain, fever and inflammation.

Interactions of Mefenamic Acid

Interactions with other medicines

  • Warfarin
  • Medicines for treatment of high blood pressure such as Diuretics (water pills)
  • Antiplatelet medicines such as Acetylsalicylic Acid
  • Antidepressant medicines
  • Aminoglycosides
  • Immunosuppressants such as Tacrolimus, Cyclosporine, Corticosteroids, Methotrexate, Mifepristone, Zidovudine. Do not take this without physician’s advice.

Interactions with food items

This medicine has food interactions with tobacco.

Dietary Restrictions of Mefenamic Acid

No information is available on dietary restrictions while you are taking Mefenamic Acid, consult your doctor or pharmacist for further details.

Dosage of Mefenamic Acid


Overdose symptoms may include kidney damage indicated by decreased urination, loss of consciousness, seizures, severe drowsiness or dizziness, severe nausea or stomach pain, trouble to breathe, unusua...
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Missed a Dose

If you missed any dose, take it as early as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to comp...
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Content Details


Dr. Arpit Verma

MBBS, MD (Pharmacology)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare expert before taking this medicine?

  • Tell your doctor-
  • If you have high cholesterol
  • If you have liver, kidney or heart disease
  • If you have any heart-related problems
  • If you have diabetes
  • If you have asthma
  • If you have a history of epilepsy
  • If you have galactose intolerance
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)
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