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Lisinopril+Amlodipine

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Molecule Summary

Uses
High blood pressure
Therapy
Anti-Hypertensive
Side Effects
Headache, dizziness, cough, diarrhoea, vomiting
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Molecule Description

Lisinopril+Amlodipine is a combination medicine used for the treatment of high blood pressure. It contains amlodipine and lisinopril, which belong to the anti-hypertensive class of medicines. It helps to reduce blood pressure and thus reduces the chances of future heart attack and stroke. Take Lisinopril+Amlodipine in the correct doses and for the exact duration as advised by your doctor. Taking this medicine regularly as prescribed by your doctor, along with other lifestyle modifications, can help you control your blood pressure better. You should also inform your doctor about your complete medical history before initiating the treatment.

Uses

For treatment of mild to moderate hypertension.

Contraindications

When should one not use Lisinopril+Amlodipine

  • If you are allergic to amlodipine, lisinopril or any other ingredients of this medicine.
  • If you are pregnant.
  • If you have a history of serious allergic reaction called angioedema (recurrent episodes of swelling).
  • If you have diabetes or kidney dysfunction and you are taking blood pressure-lowering medicine like aliskiren.
  • If you have cardiogenic shock (a sudden, severe failure of the heart to pump blood).
  • If you have severe low blood pressure.

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Cough
  • Diarrhoea
  • Vomiting

Precautions and Warnings

Pregnancy

Pregnancy

Lisinopril+Amlodipine must be avoided during pregnancy as it may possibly cause harm to the unborn baby. If you are pregnant, think you may be or are planning to have a baby, you should consult your doctor before starting this medicine.

Breast Feeding

Breast Feeding

There is limited safety data available about the use of this medicine in breastfeeding mothers. Hence, it is essential to consult your doctor before using this medicine while breastfeeding.

Driving

Driving

You may experience dizziness, headache, tiredness, etc., as a side effect. Thus you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Alcohol

There is no known interaction with alcohol along with this combination medicine. However, excessive alcohol consumption can raise blood pressure. Hence, caution is advised. Individuals with high blood pressure should avoid binge drinking.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You experience any symptoms associated with low blood pressure.
  • You have any kidney-related problems.
  • You experience allergic reactions such as swelling of the face, lips, tongue, etc.
  • You have any kind of underlying medical condition such as heart problems, liver problems, etc.
  • You experience non-productive persistent cough during the treatment.
  • You have kidney failure or diabetes, as you may develop a high level of potassium in the blood during the treatment.
  • You are elderly. Caution is advised while changing the dose for the elderly.
  • You are diabetic and taking anti-diabetic medicines. Close monitoring is advised during the first month of treatment with Lisinopril+Amlodipine.

Mode of Action

How Does It Work?

Amlodipine and lisinopril work by relaxing the blood vessels, thus making it easier for the blood to pass through the blood vessels and lowering the blood pressure. It also improves the blood and oxygen supply to the heart muscle and prevents chest pain due to angina.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Lisinopril+Amlodipine works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially if you are taking any other blood pressure-lowering medicine, water pills, mood disorders-related medicines like lithium, NSAIDs, anti-psychotic medicines, nerve-related medicines, anti-diabetic medicines and immunosuppressants like ciclosporin, etc.
  • Avoid taking this medicine along with grapefruit juice, as it may enhance the blood pressure-lowering effect of Lisinopril+Amlodipine.

Dosage

Overdose

Symptoms of overdose may include dizziness, irregular heartbeat, palpitations, anxiety, cough, etc. If you experience any of the symptoms or think you have taken too much of Lisinopril+Amlodipine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

If you have missed a dose of this medicine, take it as soon as you remember. If it is time for the next dose, then skip the missed dose and resume your usual dosing schedule. Do not compensate for the missed dose by taking an extra dose. Missing a dose of this medicine can lead to a rise in blood pressure and should be avoided.

Frequently Asked Questions (FAQs)

Lisinopril+Amlodipine is a combination of amlodipine and lisinopril, which belong to the anti-hypertensive class of medicines.

Lisinopril+Amlodipine is used for the treatment of high blood pressure. This medicine acts by relaxing the blood vessels, thereby lowering blood pressure.

You should take Lisinopril+Amlodipine exactly as told by your doctor. It can be taken at any time of the day with or without food. But try to make sure it's around the same time every day for optimum results.

No, it is not a blood thinner.

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