Hydroquinone+Mometasone+Tretinoin

• Hydroquinone+Mometasone+Tretinoin is used for the short-term treatment of moderate-to-severe melasma (dark and discoloured patches on the skin).
• It is also used to lighten the skin tone or appearance and dark spots or age spots in older people due to exposure to the sun.

When should one not use Hydroquinone+Mometasone+Tretinoin

• If you are allergic to hydroquinone, mometasone, tretinoin or similar medicines.
• If you have a skin tumour or a family history of skin tumour.
• If you suffer from any skin conditions like eczema (infected skin due to allergy), rosacea (small red pustules on the face), rashes around the mouth or damaged skin anywhere in the body.
• If you need to be exposed to the sun for prolonged periods.
• If you have any viral or fungal infections of the skin, have ulcers on the skin or are having tuberculosis.

Common side effects of this drug are:

Other General Warnings

• You have a history of allergic reactions.
• You develop skin rashes or infections after using hydroquinone+mometasone+tretinoin.
• You are a pregnant woman or a breastfeeding mother.
• You have diabetes or have Cushing's syndrome (symptoms may include weight gain, moon face, purple patches on the skin).
• Avoid unnecessary or prolonged exposure to sunlight or UV light and wear protective clothing and sunscreen.

How Does It Work?

• Hydroquinone works by inhibiting an enzyme (tyrosinase) responsible for producing a pigment called melanin. Melanin is responsible for skin pigmentation and melasma.
• Tretinoin is a metabolite of vitamin A and has anti-inflammatory properties. It is responsible for the elimination of melanin that has been formed.
• Mometasone is a steroid and works by blocking the production of inflammatory chemicals like prostaglandins and leukotrienes. Mometasone narrows and constricts blood vessels, which are dilated (widened) and leaky and allowing other inflammatory cells into the skin to promote the inflammatory response.

Interactions with other medicines

• Some medicines can affect the way hydroquinone+mometasone+tretinoin works or this medicine itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines, supplements, herbals you are currently taking or might take or are using other topically applied creams, lotion and gel to avoid any possible interaction.

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