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Hepatitis B, Purified Antigen

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Molecule Summary

Uses
Immunization against Hepatitis B Virus (HBV) infection
Therapy
Vaccine
Side Effects
Irritability, headache, drowsiness, pain and redness at the injection site and fatigue.
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Molecule Description

Hepatitis B, Purified Antigen vaccine is used for active immunisation against hepatitis B virus (HBV) infections caused by all known subtypes. It is suitable for use in neonates, infants, children, and adolescents up to 15 years of age who have not yet developed immunity. Immunisation with Hepatitis B, Purified Antigen vaccine is expected to help prevent hepatitis D, as hepatitis D (caused by the delta agent) cannot occur without the presence of a hepatitis B infection. Hepatitis B, Purified Antigen vaccine must be administered by a healthcare professional. To ensure effectiveness, all doses are required. It may cause injection site reactions, such as redness, swelling, pain, or fever, in some individuals. If these occur, inform your doctor of possible relief methods. Please disclose any medical conditions and medications to your doctor before receiving the vaccination. Pregnant or breastfeeding mothers should seek medical advice before getting the vaccine.

Uses

  • Hepatitis B, Purified Antigen vaccine is indicated for active immunization against Hepatitis B Virus (HBV) infection in individuals who are considered at risk of exposure to HBV, as advised by your doctor.
  • Immunization with Hepatitis B, Purified Antigen vaccine is also expected to prevent hepatitis D infection, as it does not occur without hepatitis B.

Contraindications

When should one not use Hepatitis B, Purified Antigen

  • If you are allergic to Hepatitis B, Purified Antigen vaccine or any of the other ingredients of this vaccine.
  • If you have a high temperature (fever).

Side effects

Common side effects of this drug are:

  • Irritability
  • Headache
  • Drowsiness
  • Pain and redness at the injection site
  • Fatigue

Precautions and Warnings

Pregnancy

Pregnancy

Hepatitis B, Purified Antigen vaccine should be used during pregnancy only when clearly needed, inform your doctor about your pregnancy status before taking this vaccine.

Breast Feeding

Breast Feeding

Limited information is available on the use of Hepatitis B, Purified Antigen vaccine during breastfeeding.

Driving

Driving

Hepatitis B, Purified Antigen vaccine has no or negligible influence on the ability to drive and use machines.

Alcohol

Alcohol

Limited information is available on the interaction of alcohol with Hepatitis B, Purified Antigen vaccine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have chronic liver disease, HIV infection, or you are a Hepatitis C carrier.
  • You have renal insufficiency (including if you have had a kidney transplant or are undergoing haemodialysis), or you have an impaired immune system.
  • You experienced a rare anaphylactic reaction after vaccination; appropriate medical treatment will be readily available.
  • You had an unrecognised Hepatitis B infection at the time of immunisation, the vaccine may not prevent the infection. If you had a suboptimal response to the initial course, you may need additional doses of the vaccine.
  • You are obese, a smoker, or have certain chronic underlying diseases.

Mode of Action

How Does It Work?

Hepatitis B, Purified Antigen vaccine works by stimulating the body's immune system to produce antibodies against the hepatitis B surface antigen (HBsAg). It contains purified HBsAg, which, when administered, triggers an immune response. This response leads to the development of protective anti-HBs antibodies that help prevent infection by neutralizing the hepatitis B virus upon exposure.

Interactions

Interactions with other medicines

  • Consult your doctor before receiving any other vaccine or medicine at the same time.
  • Discuss with your doctor any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.

Dosage

Overdose

This medicine will be given by a doctor or nurse; thus, chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor or reach out to the nearest hospital.

Missed a Dose

It is unlikely that the dose of this medicine will be missed if you are monitored in a healthcare setting. However, if you have missed a dose of this medicine, please inform your doctor or nurse immediately.

Frequently Asked Questions (FAQs)

Hepatitis B, Purified Antigen vaccine provides active immunity against Hepatitis B virus (HBV) infections and, as a result, also helps prevent Hepatitis D. It stimulates your body to produce protective antibodies.

The vaccine is expected to provide long-term protection after completing the full vaccination course. Specific duration can vary, and your doctor can advise on the need for boosters.

Avoid if you are allergic to any vaccine ingredients or have a high fever. Consult your doctor if you have other medical conditions.

Hepatitis B, Purified Antigen vaccine is given for active immunisation against the Hepatitis B virus infection in individuals at risk of exposure, as advised by your doctor. It is also expected to prevent Hepatitis D infection.

The hepatitis B vaccine stimulates your body to produce long-lasting antibodies for future protection. Hepatitis B immunoglobulin (HBIG) provides immediate, but temporary, protection against the virus, often administered after recent exposure.

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