Fluconazole

Molecule Description

Fluconazole is used to treat various fungal infections such as candida infectio

n. It is also used to prevent the occurrence of fungal infections in cancer patients. It works by inhibiting the formation of the cell wall of the infection-causing fungus. Fluconazole belongs to the class of antifungal medicines. It is not effective against viruses or bacteria. It is available in the form of a tablet, capsule, dry syrup, suspension, oral powder, injection, cream, gel, lotion, dusting powder, soap, eye & ear drops. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting fluconazole.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Fluconazole

Fluconazole is used for the treatment of fungal infections.

Contraindications of Fluconazole

When should one not use Fluconazole

If you are allergic to fluconazole or similar medicines.
If you are taking medicines like astemizole, terfenadine, cisapride, pimozide, quinidine, erythromycin, etc.

Side effects of Fluconazole

Common side effects of this drug are:

Headache
Vomiting
Diarrhoea
Nausea
Injection/Application site reactions

Precautions and Warnings of Fluconazole

Pregnancy

Can I take/use fluconazole during pregnancy?

Fluconazole should not be used during pregnancy or if you are planning to conceive, consult your doctor before using it. Use effective contraception while on treatment.

Breast Feeding

Can I take/use fluconazole while breastfeeding?

Consult your doctor before using fluconazole while breastfeeding as it passes into breastmilk.

Driving

Can I drive if I have taken/used fluconazole?

Avoid driving if you feel dizzy or experience any side effects after taking/using fluconazole.

Alcohol

Can I consume alcohol after taking/using fluconazole?

Avoid consuming alcohol after taking/using fluconazole as it may worsen the side effects.

Other General Warnings

Talk to your doctor if

You suffer from any heart, liver or kidney diseases
You have severe skin reactions
You have adrenal insufficiency (a condition where the adrenal gland does not produce sufficient steroid hormone).
You have abnormal electrolyte levels (potassium, calcium or magnesium) in your blood.

Mode of Action of Fluconazole

How Does It Work?

Fluconazole works by blocking the formation of the cell membrane of the fungus by inhibiting an enzyme. Thus, the fungi stop multiplying or die because of the non-formation of the complete cell membra...

Interactions of Fluconazole

Interactions with other medicines

Some medicines can affect the way fluconazole works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
Especially if you are taking medicines like terfenadine, voriconazole, clarithromycin, erythromycin, ranolazine, lomitapide, donepezil, pimozide, quinidine, blood thinners, painkillers or you are taki...
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The effect of contraceptive pills might be reduced. The addition of a barrier form of contraception is needed.

Content Details

WRITTEN BY

Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: In which all dosage forms is Fluconazole available?

A: Fluconazole is available in the form of a tablet, capsule, dry syrup, suspension, oral powder, injection, cream, gel, lotion, dusting powder, eye & ear drops and soap.

Q: Can Fluconazole be used for viral or bacterial infections?

A: No, Fluconazole is an antifungal medicine. It is not effective against viruses or bacteria.

References

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Last Updated on: 19 Nov 2021 | 10:55 AM (IST)

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