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Erythropoetin Alfa

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Molecule Summary

Uses
Anaemia
Therapy
Haematinics
Side Effects
Diarrhoea, nausea, vomiting, fever, stuffy nose, sore throat, increased blood pressure, blood clots
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Molecule Description

Erythropoetin Alfa is a recombinant human erythropoietin. It is used mainly for the treatment of anaemia due to kidney problems and/or medicines used in the treatment of cancer. Do not use this medicine if you are having a history of an allergy or any other bone marrow problems. Inform your doctor if you are suffering from high blood pressure or have a history of any other heart problems. Do not take this medicine without a doctor's advice if you are pregnant or are breastfeeding.

Uses

  • To treat anaemia due to kidney diseases.
  • To treat anaemia in adults who are receiving cancer treatment.

Contraindications

When should one not use Erythropoetin Alfa

  • If you are having a history of allergy (rashes, itching, skin redness, swelling of lips, eyes, difficulty in breathing or swallowing) to any of the contents of this medicine.
  • If you have red cell aplasia (a condition in which bone marrow cannot produce enough red blood cells).
  • If you have uncontrolled high blood pressure.
  • If you are due for major orthopaedic surgery (hip or knee) and you have severe heart disease, diseases of veins and arteries, recently had a heart attack or stroke, cannot take medicines to thin the blood.

Side effects

Common side effects of this drug are:

  • Diarrhoea
  • Feeling sick
  • Vomiting
  • Fever
  • Stuffy nose
  • Sore throat
  • Increased blood pressure
  • Headache, confusion, fits
  • Blood clots

Precautions and Warnings

Pregnancy

Pregnancy

It is not recommended to get this medicine if you are pregnant. Hence, inform your doctor if you are pregnant or planning to have a baby before taking this medicine.

Breast Feeding

Breast Feeding

This medicine is not recommended for use in lactating mothers. So, inform your doctor if you are breastfeeding before getting this medicine.

Driving

Driving

This medicine may affect your ability to drive, thus it is advisable not to drive or operate heavy machinery during treatment.

Alcohol

Alcohol

No, it is not advisable to take this medicine with alcohol.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have a history of blood clots.
  • You are overweight.
  • You have diabetes, heart problems, high blood pressure, liver disease, fits, porphyria (a rare inherited metabolic disorder).
  • You are bedridden long time due to surgery or illness.
  • You have anaemia due to other problems.
  • You are suffering from cancer.
  • You have serious skin conditions like Stevens-Johnson syndrome and toxic epidermal necrolysis (conditions where the skin gets peeled off and increases the chances of deadly infections).
  • You have a chronic kidney problem and you don't respond to previous erythropoietin therapy (as if you still increase the dose, it may increase the chances of problems related to heart, blood vessels, stroke, heart attack and death).
  • You are undergoing any blood tests.

Mode of Action

How Does It Work?

Erythropoetin Alfa is a recombinant human erythropoietin. It is one kind of protein that stimulates the bone marrow to produce blood cells, especially red blood cells. Thus, it relieves symptoms associated with anaemia which may be due to kidney problems or cancer treatment.

Interactions

Interactions with other medicines

  • Some medicines may affect the way Erythropoetin Alfa works, or even Erythropoetin Alfa may affect the working of some medicines.
  • Talk to your doctor particularly if you are taking cyclosporin (used for the treatment of organ transplantation), iron supplements and other blood stimulating medicines.
  • Tell your doctor about any of the other medicines you are taking which includes medicines without prescription and herbal medicines as well, as these medicines may alter the effectiveness of Erythropoetin Alfa or increase the chances of side effects.

Dosage

Overdose

This medicine is given by a healthcare professional, so it is unlikely that you will be given too much of this medicine. If you think you have been given too much medicine, tell your doctor. You may experience side effects if you have been injected too much of this medicine.

Missed a Dose

This medicine is given by a healthcare professional, so it is unlikely that you will miss a dose of this medicine. If you think a dose has been missed, contact your doctor as soon as possible to rebook.

Frequently Asked Questions (FAQs)

Erythropoetin Alfa is used in the treatment of anaemia due to kidney diseases, especially in patients who are on haemodialysis or peritoneal dialysis, who are receiving cancer treatment, who donate some of their blood before surgery so that it can be given back to them during or after an operation. It is also used in moderately anaemic adults about to have major orthopaedic surgery to reduce the need for blood transfusions and in patients with bone marrow problems.

Erythropoetin Alfa is a recombinant human erythropoietin. It is one kind of protein that stimulates the bone marrow to produce blood cells, especially red blood cells. Thus, it relieves symptoms associated with anaemia which may be due to kidney problem or cancer treatment.

You may experience diarrhoea, feeling sick, vomiting, fever, a stuffy nose and sore throat on taking this medicine.

This medicine itself can lead to an increase in blood pressure as a side effect thus, it is recommended that you inform your doctor before taking this medicine. Your doctor may advise frequent blood pressure monitoring before and during treatment with this medicine.

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