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Dalteparin

Molecule Description

Dalteparin is low molecular weight heparin anticoagulant that prevents clotting of blood.

Uses of Dalteparin

  • Unstable coronary artery (blood vessels to the heart) disease
  • Venous thromboembolism (a condition where blood clots develop in the legs)
  • Dalteparin prevents blood clots from being formed in the tubes of the equipment used during haemodialysis or haemofiltration

Contraindications of Dalteparin

When should one not use Dalteparin

  • Do not take this medicine if you have:
  • Allergy to Dalteparin or any ingredient of this medicine
  • Stomach ulcer
  • An injury or bleeding in the brain or recent surgery of the brain or eyes
  • A liver disease which may cause an increased risk of bleeding
  • Low blood platelet count (thrombocytopenia)
  • Swelling or infection in the lining of heart valves or heart

Side effects of Dalteparin

Common side effects of this drug are:

  • Itching, hives, and rash
  • Yellowing of the skin or eyes
  • Bleeding from nose or while passing stools or urine, while coughing, etc.
  • Easy bruising
  • Fast heartbeats
  • Headache, weakness, confusion
  • Increased potassium level
  • Hair loss (alopecia)
  • Bleeding from any site like brain, stomach
  • Numbness
  • Weakness

Precautions and Warnings of Dalteparin

Pregnancy

Q:
Can I take Dalteparin during pregnancy?
A:
This medicine should be used only if needed, consult with your doctor if you are pregnant or planning to become pregnant.

Breast Feeding

Q:
Can I take Dalteparin while breastfeeding?
A:
A small amount of this medicine passes into breast milk. There are no adverse effects noted for using Dalteparin during breastfeeding in the prescribed dose. Inform your doctor if you are breastfeeding.

Driving

Q:
Can I drive if I have consumed Dalteparin?
A:
There is no influence on the ability to drive.

Alcohol

Q:
Can I consume alcohol with Dalteparin?
A:
No information is available on interactions of Dalteparin when taken with alcohol, consult your doctor or pharmacist for details.

Other General Warnings

Talk to your doctor if
  • You have any condition which results in bleeding e.g., bleeding after an operation or trauma or if you have experience stroke caused by bleeding
  • Severe liver or kidney disease
  • Abnormal or low numbers of platelets (clotting cells)
  • Eye disease caused by blood pressure or diabetes
  • Uncontrolled high blood pressure
  • If you have a known history of a large amount of potassium in your blood or have a low blood pH
  • Your doctor will monitor your blood parameters regularly before and during treatment
  • If you are going to have or ever had an operation for inserting an artificial heart valve
  • If you need any other injections
  • History of any surgery in the past 6 months

Mode of Action of Dalteparin

How Does It Work?

This medicine acts as a blood thinner. It stops the existing blood clots from increasing in size and also reduces the formation of new clots in the blood. It thus prevents the reason for development of diseases like angina, thromboembolism, and deep vein thrombosis.
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Interactions of Dalteparin

Interactions with other medicines

  • Medicines used to thin your blood (e.g., Aspirin, Dipyridamole, Glycoprotein Receptor Antagonists and Warfarin)
  • Medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce pain and inflammation (e.g., Indomethacin)
  • Some medicines for gout, (e.g., Sulfinpyrazone and Probenecid)
  • Ethacrynic Acid (a water retention tablet (Diuretic))
  • You have given solution to increase the blood volume (e.g., Dextrans)
  • Medicines known as Cytostatics (used in cancer treatment)
  • Thrombolytic medications for treating heart attack (e.g., TPA Tissue Plasminogen Activator)
  • Anti-allergic medicines (e.g., Antihistamines)
  • Medicines for heart problems (e.g., Digoxin or Digitoxin)
  • Antibiotics like Tetracyclines which are used to treat bacterial infections
  • Medicines used to treat angina (Intravenous Nitroglycerine)
  • Antibiotics like high dose penicillin that are used to treat bacterial infections
  • Antimalarial medicines (e.g., Quinine)

Interactions with food items

No information is available on interactions of Dalteparin when taken with food, consult your doctor or pharmacist for further details.

Dietary Restrictions of Dalteparin

Drink plenty of liquid to prevent dehydration.

Dosage of Dalteparin

Overdose

If you happen to take an overdose of the medicine, kindly seek emergency medical care immediately. The symptoms of overdose can be – excessive bleeding through any of the external orifice or internal bleeding in vital organs. The effects of an overdose may be lethal and need immediate medical attention.
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Missed a Dose

Do not take a double dose if you have missed the dose; take the next dose as soon as you remember.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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