Cefoperazone+Sulbactam

Uses	Bacterial infection
Therapy	Antibiotic
Side Effects	Pain, inflammation and swelling at injection site, diarrhoea

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Molecule Description

Cefoperazone+Sulbactam contains cefoperazone (a cephalosporin antibiotic) and sulbactam (a beta-lactamase inhibitor). It is used to treat severe bacterial infections of the lungs, airways, urinary tract, skin, soft tissues, joints and bones. Cefoperazone+Sulbactam is a combination of antibiotics that inhibits the growth of bacteria, thus killing them. It further prevents the spread of infection. Cefoperazone+Sulbactam will be given to you by a doctor or nurse at the clinic or hospital setup. The side effects of Cefoperazone+Sulbactam are diarrhoea, nausea, vomiting, headache, pain and inflammation at the injection site. If you feel the side effects persist or the condition worsens, you must inform the doctor. Discuss with your doctor all the existing medication, supplements and disease conditions, before starting Cefoperazone+Sulbactam.

Uses

Cefoperazone+Sulbactam is used to treat severe bacterial infections like respiratory tract infection, urinary tract infection, skin and soft tissue infection, joint and bone infection, and infections of the uterus and ovaries.

Contraindications

When should one not use Cefoperazone+Sulbactam

If you are allergic to sulbactam, cefoperazone or other antibiotics of penicillins and cephalosporin class or other ingredients of Cefoperazone+Sulbactam.

Side effects

Common side effects of this drug are:

Loose stools
Nausea
Vomiting
Headache
Fever
Chills
Allergic reactions
Pain and tenderness at the injection site
Rashes with redness of skin (maculopapular rash)
Pale red bumps and swelling in the skin (urticaria)
Abnormal blood cell count

Precautions and Warnings

Pregnancy

No information is available about the safety of Cefoperazone+Sulbactam during pregnancy. Consult the doctor if you are pregnant, the doctor will tell you about the use of the medicine after assessing the need.

Breast Feeding

The components of Cefoperazone+Sulbactam passes into breast milk, inform the doctor if you are breastfeeding, the doctor will tell you about the use of the medicine after assessing the need and benefit.

Driving

It is unlikely that Cefoperazone+Sulbactam will affect the ability to drive.

Alcohol

Avoid consuming alcohol when you have taken Cefoperazone+Sulbactam as it causes reactions like flushing, sweating, headache or fast heartbeats. Avoid alcohol for at least a week after the last dose of the medicine.

Other General Warnings

Talk to your doctor if

You have an allergic reaction to antibiotics.
You have a disease of the liver and kidney.
You are taking blood-thinning medicines.
You suffer from diarrhoea when on treatment or even after discontinuing treatment.
You notice abnormal bleeding.

Mode of Action

How Does It Work?

Cefoperazone+Sulbactam kills the bacteria responsible for infections. Bacteria make an enzyme (beta-lactamases), which destroys cefoperazone. Sulbactam inactivates the enzyme and helps cefoperazone to function optimally.

Interactions

Interactions with other medicines

No interactions have been reported for Cefoperazone+Sulbactam with other medicines. However, as it contains sulbactam and cefoperazone, any interaction seen with these two components when taken alone may occur with this combination.
Medicines or solutions containing ethanol can cause flushing, sweating, headache and increased heartbeat.
If you are taking antibiotics of the aminoglycoside class, it is advisable to monitor kidney functions.
Medicine used for the treatment of gout (probenecid) may interact with this medicine.

Dosage

Overdose

The doctor or nurse will give Cefoperazone+Sulbactam. It is less likely you shall receive more of the medicine. If you experience loose motions, nausea, vomiting, headache, fits, skin rashes and allergy immediately after taking the medicine, inform the doctor as soon as possible.

Missed a Dose

You will be monitored by the doctor or nurse on when the medicine must be given to you. There are fewer chances of missing a dose. If the doctor or nurse missed a dose, inform them.

Frequently Asked Questions (FAQs)

No, avoid alcohol if you have taken Cefoperazone+Sulbactam. Avoid drinking alcohol after taking the medicine at least for a week as it causes side effects like sweating, flushing, headache or a fast heartbeat.

Inappropriate use of antibiotics means using them when not needed, for the wrong diseases, taking an inappropriate dosage and not completing the course of antibiotic treatment as prescribed by the doctor.

Cefoperazone+Sulbactam is used to treat infections caused by bacterial organisms. It treats infections of the lungs, airways, urinary tract, skin, soft tissues, joints and bones.

Cefoperazone+Sulbactam is given intravenously or intramuscularly under medical supervision. The medicine will be given by a nurse or doctor. The route of administration is usually decided by the doctor. Do not self-inject.

Yes, Cefoperazone+Sulbactam is an antibiotic medicine. It is used to treat various bacterial infections.

Yes, Cefoperazone+Sulbactam provides symptomatic relief in bacterial infections associated with UTI (urinary tract infection).

Pain and tenderness at the injection site, loose motion, headache are a few common side effects that an individual might experience. However, these symptoms are usually mild and short-lived.

Cefoperazone+Sulbactam is contraindicated if you are allergic to sulbactam, cefoperazone or other antibiotics of penicillins and cephalosporin class or other ingredients of Cefoperazone+Sulbactam.

The dose and frequency of Cefoperazone+Sulbactam vary among individuals depending on the severity of the infection and the patient's response to the treatment. Do not self-inject.