Omeprazole+Domperidone

Molecule Description

Omeprazole+Domperidone is a combination medicine. It is an anti-reflux medicine

used for the treatment of gastrointestinal reflux disease (GERD) which does not respond to omeprazole. It provides relief from symptoms of acid reflux disease like heartburn and chest discomfort. Both the medicines, together work by reducing the amount of acid produced in the stomach and improves the mortality in the gut. Thus, it reduces the backflow of stomach content to the food pipe. Omeprazole+Domperidone is available in the form of tablet, capsule, injection.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Omeprazole+Domperidone

Omeprazole+Domperidone is used to treat gastrointestinal reflux disease (GERD), not responding to omeprazole alone.

Contraindications of Omeprazole+Domperidone

When should one not use Omeprazole+Domperidone

If you are allergic to omeprazole+domperidone
If you have problems with your heart, liver or kidney.
If you suffer from bleeding in the digestive system.
If you have problems relating to the bones such as osteoporosis and a fracture.
If you have any tumour of the pituitary gland (Prolactin pituitary tumours).
If you have low magnesium levels in your blood.

Side effects of Omeprazole+Domperidone

Common side effects of this drug are:

Headache
Dizziness
Stomach pain
Diarrhoea
Dry mouth
Injection site reactions

Precautions and Warnings of Omeprazole+Domperidone

Pregnancy

Can I take omeprazole+domperidone during pregnancy?

It is not advised to take omeprazole+domperidone during pregnancy until it is considered essential by the doctor and potential risks justify the benefits.

Breast Feeding

Can I take omeprazole+domperidone while breastfeeding?

Omeprazole+Domperidone passes in the breastmilk in a small amount. Your doctor may prescribe you this medicine while you are breastfeeding, only if it is necessary. Inform your doctor if you are a nursing mother.

Driving

Can I drive if I have taken omeprazole+domperidone?

Omeprazole+Domperidone may cause dizziness, thus you need to be cautious while driving.

Alcohol

Can I consume alcohol with omeprazole+domperidone?

Avoid consuming alcohol with omeprazole+domperidone, as it may worsen the side effects.

Other General Warnings

Talk to your doctor if

You suffer from any heart problems such as heart failure, heart rhythm problems, electrolyte imbalance
You have problems with your liver or kidney.
You have a stomach tumour/cancer
You are taking medicines to treat HIV.
You have a history of fractures or have osteoporosis or are taking steroids.
You develop watery/black stools or fever after taking omeprazole+domperidone.
You get rashes on your skin on exposure to sun after taking this medicine.
Your blood magnesium levels may drop, if you are taking this medicine for more than three months. Your doctor may perform regular tests.
Taking omeprazole+domperidone for more than one year may increase the chances of developing bone fractures.

Mode of Action of Omeprazole+Domperidone

How Does It Work?

A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Omeprazole works by binding to this proton pump in stomach cells, thus blocking acid secretion.
Domperidone works by increasing the motility of the stomach and intestines so that acid does not reflux back into the food pipe.

Interactions of Omeprazole+Domperidone

Interactions with other medicines

Some medicines can affect the way omeprazole+domperidone works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines...
Read more
Especially if you are taking medicine to treat your heart problems, psychiatric illnesses, HIV infection, fungal or bacterial infections or are taking blood thinners or medicines like methotrexate, ta...
Read more
Medicines like clopidogrel, atazanavir, nelfinavir, erythromycin, posaconazole, ketoconazole, itraconazole should not be used along with this combination.

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Is omeprazole+domperidone an antibiotic?

A: No, omeprazole+domperidone is not an antibiotic, it is an anti-reflux medicine.

Q: In which all dosage forms is omeprazole+domperidone available?

A: Omeprazole+Domperidone is available in the form of tablet, capsule, injection.

References

View All

Last Updated on: 19 Nov 2021 | 10:55 AM (IST)

Share This With Your Friends

Recent articles

See All

High Cholesterol Diet – Foods to Eat & Avoid!

Introduction Heart disease is the primary cause of deaths around the world. Having too much cholesterol can lead to severe cardiac issues. Thankfully, you can control and reduce the cholesterol levels by watching what you eat, i.e. the right cholesterol foods. Everything that you ingest has an impact on your cholesterol levels. Here is our

Your Ultimate Guide To A Balanced Diet For Diabetes

Introduction Type 2 Diabetes Mellitus is a chronic metabolic disorder affecting more than 100 million people in India. Diabetes occurs either due to insufficient insulin production, insulin resistance, or both which results in high levels of glucose in blood. Managing diabetes is crucial because uncontrolled diabetes can have serious complications like vision loss, kidney failure,

Benefits of Figs Soaked in Water Overnight: Exploring Nutritional Advantages

Key Highlights: Introduction Figs are versatile and scrumptious fruit that has been revered for its proposed nutritional benefits since ancient times. This little fruit, filled with a burst of sweetness, is a powerhouse of essential nutrients that may enhance your well-being. When soaked in water overnight, figs can make a valuable addition to your daily

Is Dry Ice Dangerous?

Introduction: Recently, dry ice has been in the news due to an unfortunate incident that occurred at a cafe in Gurugram, Haryana. Five diners unwittingly consumed dry ice, mistaking it for mouth freshener. As per news reports, the diners suffered serious injuries to their food pipe and oral cavity after accidentally ingesting the dry ice.

Bubonic Plague Reported: Are We In Danger?

Bubonic plague, which became notorious during the 14th Century in Europe and swept through India from the 1890s to 1910s, is caused by bacteria called Yersinia pestis. Contrary to popular belief, this plague isn’t caused by rat bites. The cause of bubonic plague is the bite of infected fleas. These fleas live in the hairs

Simple and Effective Skin Care Routine

Introduction Healthy skin is indicative of the quality of diet and lifestyle one follows. The largest organ of the human body and often overlooked, the skin acts as a barrier and prevents the external components from entering the inside of the body. This entails that, at times, it is exposed to critically harsh conditions, and

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.