Lupride Depot 3.75mg Powder For Injection
Description
Lupride Depot 3.75mg injection is a prescription medicine that contains Leuprorelin (also called leuprolide) as its active ingredient. It belongs to the class of medicines known as gonadotropin-releasing hormone (GnRH) agonists. In men, it is mainly prescribed for the treatment of prostate cancer by lowering testosterone levels, which helps in slowing down the growth of cancer cells.
In women, Lupride Depot 3.75mg injection is used to manage uterine fibroids and endometriosis, conditions that often cause painful periods, excessive bleeding, and pelvic pain. Reducing estrogen levels helps control these symptoms. Additionally, this injection is prescribed in children to treat precocious puberty (very early puberty) by delaying further sexual development until the appropriate age.
This injection is administered only by a doctor or nurse in a hospital or clinic setting, and you should never attempt to self-inject it at home. The dosage and duration of treatment depend on your medical condition and response to therapy.
Before starting treatment with Lupride Depot 3.75mg injection, it is important to inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding. This medicine should not be used during pregnancy unless specifically advised by the doctor.
You should also share your complete medical history, including any history of diabetes, heart disease, bone weakness (osteoporosis), or hormonal disorders. Regular medical check-ups and monitoring may be necessary during treatment to ensure the safe and effective use of this medicine.
Product Summary
Offer Price | ₹2941.32 |
You Save | ₹326.81 (10% on MRP) |
Contains | Leuprolide / Leuprorelin(3.75 Mg) |
Uses | Prostate cancer in men, uterine fibroids and endometriosis in women and early puberty in children |
Side effects | Injection site reactions, headache, nausea, fatigue, weight changes, hot flushes |
Therapy | ANTI-NEOPLASTIC |
Uses
- Lupride Depot 3.75mg injection is used in men for the treatment of prostate cancer.
- It is also used in women to treat uterine fibroids and endometriosis (causing symptoms such as menstrual cramps, excessive bleeding, pain while urinating, etc).
- This medicine is also used in children to treat early puberty.
Contraindications
- If you are allergic to Leuprorelin or any other ingredients of Lupride Depot 3.75mg injection.
- If you experience abnormal or irregular vaginal bleeding, which the doctor is unaware of.
- If you are pregnant, planning a pregnancy or are breastfeeding.
Side effects
- Injection site reactions such as pain, redness, swelling
- Tiredness
- Sweating
- Hot flashes
- Weight gain or loss
- Loss of appetite
- Altered mood
- Joint or bone pain
- Headache
- Nausea
- Muscle weakness
- Difficulty in sleeping
- Low sex drive
- Blurred vision, dizziness (uncommon)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have diabetes.
- You have problems with your heart, liver or kidneys.
- You have or are at an increased risk of having a bone condition called osteoporosis.
- You consume alcohol regularly.
- You suffer from any mental health problems.
- You continue to have your periods after starting Lupride Depot 3.75mg injection.
- You notice severe or abnormal vaginal bleeding.
- You or your partner need to use proper birth control measures (non-hormonal contraception) while on treatment.
Directions for Use
- Lupride Depot 3.75mg injection will be given to you in hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
Storage and disposal
- Store Lupride Depot 3.75mg injection under the conditions mentioned on the pack.
- Keep it out of reach of children and pets.
Quick Tips
- Lupride Depot 3.75mg Injection should only be given by a doctor or nurse; do not self-inject.
- Administer the injection at the same scheduled interval every month, or as directed by your doctor.
- Inform your doctor if you experience unusual bone pain, mood changes, or difficulty urinating.
- Women should use effective contraception during treatment, as this medicine should not be used in pregnancy.
- Follow a healthy diet and lifestyle to support bone and overall health during long-term use.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Some medicines can affect the way Lupride Depot 3.75mg injection works, or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.
- Especially, if you are taking medicines to treat your heart problems (like quinidine, procainamide, amiodarone, sotalol), medicines to treat your mental health problems (like clozapine, risperidone, quetiapine) and antibiotics (like moxifloxacin)....
Interactions with food items
- No specific food interactions are reported with Lupride Depot 3.75mg Injection.
- Maintain a balanced diet rich in calcium and vitamin D, as the medication can reduce bone density over the long term.
- Limit alcohol and caffeine intake, as they may worsen bone loss and increase side effects like dizziness.
- Stay well-hydrated and include fresh fruits, vegetables, and whole grains to support your overall health.
Content Details

Dr. Arpit Verma
MBBS, MD, CCEBDM Diabetology

Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What is the use of Lupride Depot 3.75mg injection?
- Lupride Depot 3.75mg injection is used in men for the treatment of prostate cancer.
- It is also used in women to treat uterine fibroids and endometriosis (causing symptoms such as menstrual cramps, excessive bleeding, pain while urinating, etc.).
- This medicine is also used in children to treat early puberty.
Q: What should be discussed with my healthcare professional before I start the treatment with Lupride Depot 3.75mg injection?
- Inform the doctor about your detailed medical & surgical history.
- Inform your doctor if you have heart, liver or kidney disease or have fits.
- Inform your doctor if you are pregnant, breastfeeding or planning to have a baby.
- Lupride Depot 3.75mg injection may interact with other medicines, hence, inform your doctor if you are taking any other medicines including supplements or herbal products. Also, inform your doctor if you are stopping any medicine....
Q: Does Lupron Depot 3.75 need to be refrigerated?
- Store Lupride Depot 3.75 under the conditions mentioned on the pack.
- It is usually stored at room temperature, protected from moisture.
- Keep it out of reach of children and pets.
Q: How fast does Lupron injection 3.75 take to work?
Q: How do you take Lupride Depot injections?
- Lupride Depot injection will be given to you in the hospital by your doctor or nurse. Do not self-inject this medicine.
- Follow any instructions suggested by the doctor or nurse during the procedure or for aftercare.
Q: Can Lupride Depot 3.75mg injection affect fertility?
Q: What are the common side effects of Lupride Depot 3.75mg injection?
References
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