Cyramza 100mg Vial Of 10ml Solution For Infusion

• Cyramza solution for infusion is used by cancer specialists in the treatment of:
• Gastric cancer
• Gastro-oesophageal junction adenocarcinoma
• Colorectal cancer (metastatic)
• Non-small cell lung cancer (NSCLC)
• Hepatocellular carcinoma

• If you are allergic to ramucirumab or any of the other ingredients of Cyramza solution for infusion
• If you have non-small cell lung cancer (NSCLC) and have tumour cavitation or tumour involvement of major blood vessels.

• Headache
• Diarrhoea
• Rash
• Abdominal pain
• Thrombocytopenia (low levels of platelets in the blood)
• Neutropenia (low levels of white blood cells, particularly neutrophils)
• Hypokalaemia (low levels of potassium in the blood)
• Hyponatraemia (low levels of sodium in the blood)
• Hypoalbuminaemia (low levels of albumin, a protein in the blood)
• Hypertension (high blood pressure)
• Epistaxis (nosebleed)
• Proteinuria (protein in the urine)
• Peripheral oedema (swelling in the hands, feet, or legs)
• Infusion-related reactions (side effects like chills, fever, or difficulty breathing during or after an IV infusion)

Other General Warnings

• You have kidney disease or have had a kidney transplant, as there is limited safety data for severe renal impairment.
• You have liver disease or severe liver cirrhosis, especially if associated with hepatic encephalopathy or clinically significant ascites.
• You have uncontrolled hypertension, as treatment should not begin until blood pressure is well controlled.
• You have a history of arterial thromboembolic events, such as myocardial infarction or stroke.
• You are taking anticoagulants, NSAIDs, or antiplatelet agents, as these may increase the risk of bleeding.
• You have a history of gastrointestinal perforations or severe bleeding, as ramucirumab increases these risks.
• You have had recent surgery or have non-healing wounds, as ramucirumab may affect wound healing.
• You have a history of aneurysms or artery dissections, as VEGF inhibitors may promote these conditions.
• You are pregnant or planning to become pregnant, as the effects on fetal development are unknown.
• You are breastfeeding, as it is unclear if ramucirumab passes into breast milk.
• You have a history of infusion-related reactions or hypersensitivity, as severe reactions may occur.
• You have proteinuria or kidney function issues, as ramucirumab can worsen proteinuria and renal conditions.
• You are elderly and being treated for NSCLC, as older patients may experience reduced efficacy or increased adverse events.
• You have experienced neurological symptoms such as seizures, headaches, or visual disturbances, as these may indicate posterior reversible encephalopathy syndrome (PRES).
• You have stomatitis, as this side effect may require prompt symptomatic treatment.
• You are sodium-sensitive or on a sodium-restricted diet, as this medication contains sodium.

Overdose

Missed a Dose

How Does It Work?

Interactions with other medicines