Tretinoin+Clindamycin

When should one not use Tretinoin+Clindamycin

• If you are allergic to Clindamycin, Tretinoin or any other components of Tretinoin+Clindamycin.
• If you have a history of inflammatory bowel disease or any other problems with your intestines.
• If you have ever developed diarrhoea after using any antibiotic medicine.
• If you are pregnant or are planning a pregnancy.
• If you or any of your family member has skin cancer.
• If you are suffering from any other skin conditions.

Common side effects of this drug are:

• Burning sensation, itching, irritation, redness of skin at the area where this medicine is applied
• Skin peeling
• Dry skin

Other General Warnings

• You have a history of any allergic skin reactions.
• You notice dryness, irritation and peeling of skin after using this medicine.
• You experience an allergic reaction after using this medicine.
• You are also applying other topical medicines (cream, ointment, lotion, etc).
• You do not notice any improvement in your condition after applying this medicine for two weeks.
• Do not apply Tretinoin+Clindamycin on inflamed skin.
• Avoid contact with your eyes, nose and mouth.
• Avoid being in the sunlight for too long as this medicine may make you more sensitive to the sun.
• Do not use Tretinoin+Clindamycin for any other conditions than that prescribed by the doctor.

How Does It Work?

• Tretinoin+Clindamycin works by the combined action of its two components - Clindamycin and Tretinoin.
• Clindamycin is an antibiotic, which works by inhibiting growth and multiplication of acne-causing bacteria.
• Tretinoin is a form of Vitamin A. It also has anti-inflammatory properties and works by irritating the skin and causing the skin cells to divide and die more rapidly, speeding up turnover of the cells and thus encouraging new cell growth and replenishing the skin.

Interactions with other medicines

• Tretinoin+Clindamycin is applied externally on the skin, thus it is less likely to interact with other medicines taken orally. However, it may interact with other topically applied creams, lotion and gel. Discuss with your doctor if you are already on another topical gel or creams.
• Tretinoin+Clindamycin should be used with caution along with medicated soaps and cleaners, as it may cause dryness of the skin.
• Concomitant use along with medicines that contain steroids should be avoided.
• Medicines like warfarin, acenocoumarol and fluindione should be used cautiously with Tretinoin+Clindamycin.

Overdose

• As Tretinoin+Clindamycin is meant for external application, cases of an overdose are unlikely. However, excessive use of this medicine for a prolonged duration may cause skin redness, peeling and discomfort. It may also cause symptoms like nausea, vomiting, stomach pain and diarrhoea.
• If you experience any of the symptoms or upon accidental ingestion, contact your doctor immediately or visit the nearest hospital.
• If you have overapplied it, wipe out the excess medicine with a tissue or cotton.

Missed a Dose