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Molecule Description

Serratiopeptidase is a proteolytic enzyme used to treat pain and inflammation. It is also called Serrapeptase.

Uses of Serratiopeptidase

  • Bony and joint pain (osteoarthritis, rheumatoid arthritis, osteoporosis, fibromyalgia)
  • Headache (migraine, tension headache)
  • Inflammation of sinuses, pharynx and sinuses
  • Ear infections (otitis media)
  • Blood clot
  • Postoperative wound or traumatic swelling
  • Carpal tunnel syndrome
  • After dental extraction
  • Chronic airway diseases (bronchitis)
  • Ulcer and inflammation in the colon (ulcerative colitis)
  • Blood clot (thrombophlebitis)
  • Fibrocystic breast disease

Contraindications of Serratiopeptidase

When should one not use Serratiopeptidase

  • Bleeding disorders
  • Liver disorders
  • Kidney damage
  • Swelling due to the abscess

Side effects of Serratiopeptidase

Common side effects of this drug are:

  • Allergic reactions- rash, fever
  • Stomach ache
  • Bleeding in patients of bleeding disorders
  • Nausea

Precautions and Warnings of Serratiopeptidase


Can I take Serratiopeptidase during pregnancy?
The effect of Serratiopeptidase on the fetus is not known. Consult your doctor if you are pregnant, your doctor will tell you about the use of this medicine after assessing the benefits over risks.

Breast Feeding

Can I take Serratiopeptidase while breastfeeding?
Tell your doctor if you are breastfeeding as no information is available on the use of Serratiopeptidase. If you are breastfeeding, your doctor will tell you about the use of this medicine after assessing the benefits over risks.


Can I drive if I have consumed Serratiopeptidase?
No information is available on the ability to drive or use machines. However, if you observe or experience any side effects, it is advised not to drive or use tools. Contact your doctor or pharmacist for further information.


Can I consume alcohol with Serratiopeptidase?
It is not safe to drink alcohol with this medicine.

Other General Warnings

Talk to your doctor if
  • You are suffering from any bleeding disorder or taking any blood-thinning medicines
  • You are allergic to any medicines

Mode of Action of Serratiopeptidase

How Does It Work?

It causes a breakdown of insoluble protein byproduct of blood coagulation known as fibrin.

Interactions of Serratiopeptidase

Interactions with other medicines

  • Aspirin
  • Clopidogrel
  • Dalteparin
  • Diclofenac
  • Enoxaparin or Heparin
  • Warfarin

Interactions with food items

No information is available on interactions of Serratiopeptidase when taken with food, consult your doctor or pharmacist for further details.

Dietary Restrictions of Serratiopeptidase

No information is available on dietary restrictions while you are taking Serratiopeptidase, consult your doctor or pharmacist for details.

Dosage of Serratiopeptidase


Seek medical attention immediately if you suspect an overdose.

Missed a Dose

If you miss a dose, take the missed dose as soon as you remember it. If it is almost time for the next dose, then skip the missed dose and continue with the regular dosage. Do not take a double dose to compensate for the missed dose.
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Content Details


Dr. Rukman Mecca

MBBS, MD (Community Medicine)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: What should I discuss with my healthcare expert before taking this medicine?

  • Tell your doctor if-
  • You are suffering from any bleeding disorder
  • You are taking any blood thinner medicines
  • If you are allergic to any medicines
  • Give a complete medical and surgical history

Q: Is this medicine addictive?

A: This medicine is not addictive.
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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