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Molecule Description

Levosulpiride is used to treat upper abdominal pain, bloating, nausea, vomiting

and irritable bowel movement. It is also used in adults for depression and schizophrenia. It works by blocking the effect of dopamine receptors present in the brain. Levosulpiride is available in the form of a tablet, capsule, injection. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.


Uses of Levosulpiride

  • Levosulpiride is used for the treatment of upper abdominal pain and bloating, nausea, vomiting, irritable bowel movement, irregular emptying of the stomach in diabetic patients,
  • It is also used for the treatment of depression and schizophrenia in adults.

Contraindications of Levosulpiride

When should one not use Levosulpiride

  • If you have allergic to levosulpiride or similar medicines.
  • If you have any psychiatric disorder such as fits, sudden change in mood.
  • If you are pregnant or breastfeeding.
  • If you are suffering from changes in breast tissues and nodules and have a high level of prolactin hormone.
  • If you suffer from a condition called pheochromocytoma (adrenal gland cancer that gives rise to high blood pressure).
  • If you are suffering from bleeding or blockage of the stomach and intestine.
  • Levosulpiride should not be used in patients below 18 years of age.

Side effects of Levosulpiride

Common side effects of this drug are:

  • Sleepiness
  • Irregular menstrual cycle
  • Swelling of breasts in men
  • Low blood pressure
  • Uncontrolled involuntary muscle movements
  • Injection site reactions

Precautions and Warnings of Levosulpiride



Can I take levosulpiride during pregnancy?
Consult with your doctor before taking the levosulpiride during pregnancy as limited safety data is available.

Breast Feeding

Can I take the levosulpiride while breastfeeding?
Consult with your doctor before taking levosulpiride while breastfeeding as limited safety data is available.


Can I drive if I have taken the levosulpiride?
It is advised to avoid driving after taking levosulpiride as it may alter the ability to drive.


Can I consume alcohol with levosulpiride?
Avoid consuming alcohol with levosulpiride

Other General Warnings

Talk to your doctor if
  • You have a history or a family history of heart disease.
  • You are suffering from any psychiatric disorder and are on medications for the same.
  • You experience dizziness, drowsiness after taking levosulpiride.
  • You consume alcohol too often or regularly.

Mode of Action of Levosulpiride

How Does It Work?

Leisure regulates the action of the brain and controls the mechanism of the stomach by increasing gut motility and intestinal movement hence preventing reflux.

Interactions of Levosulpiride

Interactions with other medicines

  • Some medicines can affect the way levosulpiride works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Especially, if you are taking medications that neutralise acidity in the stomach (containing aluminium and magnesium hydroxide).
  • The effect of levosulpiride on gut motility can be altered by muscle relaxants like alkaloids, atropine, dicyclomine, painkillers like codeine, opium, ibuprofen, aspirin and naproxen.

Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: In which all dosage forms is Levosulpiride available?

A: Levosulpiride is available in the form of a tablet, capsule, injection.

Q: What is Levosulpiride used for?

A: Levosulpiride is used to treat stomach acid reflux, indigestion, irritable bowel movement, depression & schizophrenia.
Last Updated on: 20 Nov 2021 | 11:49 AM (IST)

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