Ketorolac Tromethamine

Molecule Description

Ketorolac Tromethamine is a Non-Steroidal Anti-Inflammatory Drug (NSAID) prescr

ibed short term for relief of moderate to severe pain. The medicine is not to be used beyond five days.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Ketorolac Tromethamine

Moderate to severe pain, usually for pain after surgery
To prevent and relieve eye inflammation after eye surgery

Contraindications of Ketorolac Tromethamine

When should one not use Ketorolac Tromethamine

Do not take if you have allergy to Ketorolac Tromethamine, other NSAIDs or Aspirin.

Side effects of Ketorolac Tromethamine

Common side effects of this drug are:

Allergic reaction like - fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat, running, stuffy nose, sneezing
Inflammation of the eye, swelling of eyelid/ eye, puffiness, itchy eyes, red eye, vision trouble
Inflammation of the intestine, indigestion
Diarrhea, nausea, vomiting, abdominal pain, fullness in stomach, sweating
Dizziness, drowsiness, headache
Bleeding from unusual sites
Mood and behavioral changes and hallucinations
Blisters on skin, peeling, redness, swelling
Unusual weakness, tiredness, joint and muscle pain
Little or no urination, difficulty in passing urine
Dark stool/ urine or vomitus

Precautions and Warnings of Ketorolac Tromethamine

Pregnancy

Can I take Ketorolac Tromethamine during pregnancy?

This medicine (especially oral or intravenous) is known to cause serious adverse effects to the unborn baby if consumed by the mother during pregnancy (especially in the last three months). Thus, it is not recommended in pregnancy.

Breast Feeding

Can I take Ketorolac Tromethamine while breastfeeding?

Ketorolac Tromethamine is excreted in mother’s milk and may cause growth problems in infants. Hence, this medicine should be avoided during breastfeeding.

Driving

Can I drive if I have consumed Ketorolac Tromethamine?

Taking this medicine may lead to cause temporary blurred vision. Do not drive until you feel well.

Alcohol

Can I consume alcohol with Ketorolac Tromethamine?

Alcohol may increase the side effects of drowsiness and dizziness.

Other General Warnings

Talk to your doctor if

You have diabetes, eye infections, arthritis, stomach ulcers, anaemia, asthma or history about any eye surgery.

Mode of Action of Ketorolac Tromethamine

How Does It Work?

Ketorolac Tromethamine being an anti-inflammatory medicine helps in inhibiting and blocking substances like prostaglandin that cause inflammation, pain, swelling and fever.

Interactions of Ketorolac Tromethamine

Interactions with other medicines

Ketorolac Tromethamine may increase the side effects when used with other NSAIDs, Cyclosporine, Metformin, Methotrexate, Quinolones
Ketorolac may reduce efficacy of Diuretics (water pill) or Angiotensin Converting Enzyme (ACE) inhibitors (e.g., Enalapril)
Probenacid may increase the risk of side effects of Ketorolac Tromethamine
Anticoagulants like Heparin, Warfarin, Clopidogrel, Aspirin, etc. These may increase the risk of bleeding

Interactions with food items

No information is available on interactions of Ketorolac Tromethamine when taken with food, consult your doctor or pharmacist for further information.

Dietary Restrictions of Ketorolac Tromethamine

No information is available on dietary restrictions while you are taking Ketorolac Tromethamine consult your doctor or pharmacist for further information.

Dosage of Ketorolac Tromethamine

Overdose

The symptoms of overdose are dizziness, drowsiness, seizures, loss of consciousness, nausea, stomach pain, decreased urination, difficulty in breathing, tremors, dark stool and vomit, bleeding from un...

Missed a Dose

Take your missed dose as early as possible. Skip the missed dose & do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Abhishek B L

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Ketorolac Tromethamine?

You must inform your doctor if you are suffering from any of the following if you have blood disorder, bleeding, clotting disorders, heart, kidney or liver diseases, diabetes, high blood pressure, ast...
Read more
Inform your doctor if you are taking any other medicines, supplements or herbs
Inform if you smoke or drink alcohol

Q: When and how to consume the medicine?

A: You must take medicine precisely the way it is prescribed by the physician. The medication is usually given in an injection form. It may also be provided through the nose or orally. The injection will be administered by a healthcare professional into the vein or muscle at a clinic or hospital, or you will be taught how to take it at home. Do not use the medicine for more than five days. Use disposable needles and syringes. Keep them away from children and pets. Discard the medicine if it becomes cloudy, discolored, particulate or if the vial is damaged.

Q: Can I use this medicine in children?

A: Ketorolac Tromethamine is not recommended in children.

References

EMA. Ketorolac. [Accessed 06 Sep 2019] (online)

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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