PharmEasy logo
Select Pincode
Don’t have a prescription?
Get Started

Iloperidone

Molecule Description

Iloperidone belongs to ‘atypical antipsychotics’ class of medicines.

Uses of Iloperidone

It is used to treat recent mental disorders characterized by mood and behavioral changes like feeling things that are unreal or did not happen (acute schizophrenia).

Contraindications of Iloperidone

When should one not use Iloperidone

  • If you have an allergy to Iloperidone or any of its ingredients
  • If you have any psychiatric illness due to age-related brain problems such as memory, thinking or language problems (dementia related psychosis)
  • If you have severe liver problems

Side effects of Iloperidone

Common side effects of this drug are:

  • Drowsiness
  • Dry mouth, dizziness, fatigue, running or stuffy nose
  • Feeling sleepy (lethargy), fast heartbeats (tachycardia), weight gain
  • Prolonged and slow heart rate (prolonged QTC interval) which can be fatal
  • Dizziness, falling or fainting when getting up from sitting or lying position (orthostatic hypotension)
  • High blood sugar and cholesterol levels which may increase the risk of heart disease and brain stroke
  • Very high fever, elevated heart rate and blood pressure, tremors, stiff muscles and confusion – neuroleptic malignant syndrome (rare but serious)
  • Severe allergic reactions including swelling of face, lips and throat causing swallowing and breathing problems, with or without rashes, itching, skin peeling and blisters (rare but serious)

Precautions and Warnings of Iloperidone

Pregnancy

Q:
Can I take Iloperidone during pregnancy?
A:
Iloperidone should be used with caution during the first six months of pregnancy (2 trimesters) only if other alternatives are not available. It should be avoided during the 3rd trimester (or last three months) of pregnancy.

Breast Feeding

Q:
Can I take Iloperidone while breastfeeding?
A:
It is unknown if Iloperidone is secreted in breast milk. Still, because it has the potential to cause unwanted effects in the baby, it is recommended to avoid this medicine in breastfeeding mothers.

Driving

Q:
Can I drive if I have consumed Iloperidone?
A:
This medicine may cause problems such as dizziness or drowsiness, reduced alertness, thinking learning and movement problems. You are advised to drive if you experience no such symptoms.

Alcohol

Q:
Can I consume alcohol with Iloperidone?
A:
Avoid alcohol as it can increase the side effects due to Iloperidone.

Other General Warnings

Talk to your doctor if
  • Inform your doctor if you develop any of the following:
  • Increase in thirst, urination or hunger (due to high blood sugars)
  • Low white blood cell counts
  • Breast pain and discharge, irregular menstrual periods or impotence in males (due to increased levels of prolactin hormone)
  • Reduced body temperature
  • Suicidal thoughts
  • History of seizures (fits)
  • Prolonged erection (priapism)
  • Uncontrolled movements of the face, tongue or other parts of the body (tardive dyskinesia) which may become permanent. You are advised to inform the doctor if you experience any such symptoms
  • You should tell your doctor before surgery regarding all the products you use (including prescription medicines, non-prescription medicines and herbal products)

Mode of Action of Iloperidone

How Does It Work?

Iloperidone acts by reducing or suppressing the activity of the brain and thus calming the person. It does this by blocking the actions of substances that transmit signals in the brain (neurotransmitters such as Dopamine and Serotonin).
read less

Interactions of Iloperidone

Interactions with other medicines

  • Ketoconazole (antifungal)
  • Certain antidepressants (Fluoxetine, Paroxetine)
  • Few medicines which may increase the risk of irregular heartbeat (3 Procainamide, Quinidine, Sotalol)
  • Certain antibiotics (such as Gatifloxacin, Moxifloxacin, Pentamidine)
  • Antianxiety medicines (Prochlorperazine, Chlorpromazine, Trifluoperazine, Perphenazine, etc.)
  • Methadone (opioid pain killer)

Interactions with food items

Iloperidone can be taken before or after meals.

Dosage of Iloperidone

Overdose

Take Iloperidone in the exact dose as prescribed by your doctor. Inform the doctor in case of any overdose symptoms such as drowsiness, rapid heartbeat or feeling lightheaded.

Missed a Dose

Take the missed dose as early as you remember. If it is time for the next dose (less than 6 hours), skip the missed dose and continue your regular dosing schedule. Do not take a higher or a double dose of Iloperidone to compensate for the missed dose.
read less

Content Details

WRITTEN BY
doctor

Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)

REVIEWED BY
doctor

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

^

Q: Is there anything else I need to know before taking Iloperidone?

  • Iloperidone may affect your heart rhythm so inform the doctor if you experience any irregular, prolonged, forceful heartbeats or abnormal heart rhythms
  • There could be potential weight gain due to Iloperidone as is the case with most of the medicines used to treat psychiatric illness
  • This medicine may also cause you to fall and increase the risk of fractures
  • Iloperidone can cause some severe side effects like prolonged and slow heart beats (prolonged QTC interval), irregular heartbeats and rhythms, uncontrollable movements of the face and tongue, swallowing problems, high blood sugars and cholesterol levels, menstrual irregularities in females, thinking and judgment problems, etc.
    read less
  • You are advised to be cautious if you or anyone close to you is taking this medicine and report any observed side effects to the doctor promptly
  • Iloperidone should not be used in patients less than 18 years of age and patients with liver disease

Q: Is Iloperidone an effective medicine?

  • Iloperidone is believed to be an effective medicine to treat schizophrenia and is widely used with success. It works well and is better tolerated (lesser side effects) than most of the medicines used to treat this disorder
    read less
  • This medicine has to be started at low doses and the required dose should be reached gradually. This is because Iloperidone may cause dizziness when standing up from sitting or lying position (orthostatic hypotension), especially during the start of the treatment
    read less
  • Due to this reason, it may take time for you to experience any relief of symptoms (like 1-2 weeks)
  • Most of the side effects of Iloperidone occur when high doses are used and this medicine is usually safe at lower doses
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

Share This With Your Friends

app-share-iconapp-share-iconapp-share-icon
Recent articles
View More
Today
Allergy March – Have you heard of it? By #AllergyFree- A Sanofi India initiative
Very common in children, an allergy march is when a kid starts to get allergies in a specific order. It’s a condition that starts from eczema, then food allergies and hay feve...
Yesterday
Is Moderna Vaccine 95% Effective for COVID-19?
Last week, Moderna announced its experimental vaccine against COVID-19 almost 95% effective, marking it to be the first one in the quest to end the pandemic. This is the secon...
Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
1 Lakh+ Products
We maintain strict quality controls on all our partner retailers, so that you always get standard quality products.
Secure Payment
100% secure and trusted payment protection
Easy Return
We have a new and dynamic return window policy for medicines and healthcare items. Refer FAQs section for more details.
Download the App for Free