Gliclazide

Molecule Description

Gliclazide belongs to a group of medicines called oral antidiabetic medicine. I

t is a blood sugar lowering medicine used in diabetes mellitus when it is not controlled by diet, exercise, and weight loss alone.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Gliclazide

Gliclazide is used to treat Type 2 diabetes mellitus.

Contraindications of Gliclazide

When should one not use Gliclazide

If you have an allergy to Gliclazide or other Sulfonylureas
If you have Type1 diabetes or diabetic ketoacidosis (ketone bodies and sugar in your urine)
If you are suffering from severe kidney or liver disease
If you are pregnant and breastfeeding

Side effects of Gliclazide

Common side effects of this drug are:

May lead to low blood glucose levels causing fainting, sweating, and giddiness(see other warnings)
Headache, nausea, diarrhea, stomach pain, vomiting, and anemia are also seen
Allergic skin reactions like rash redness, hives
Rapid swelling eyelids, face, lips, mouth, tongue or throat, breathing difficulty (angioedema)

Precautions and Warnings of Gliclazide

Pregnancy

Can I take Gliclazide during pregnancy?

This medicine should not be taken during pregnancy.

Breast Feeding

Can I take Gliclazide while breastfeeding?

You must avoid Gliclazide while you are breastfeeding. Because limited information is available on the use of Gliclazide during breastfeeding, alternative medicine may be preferred. If you are on Gliclazide (prescribed by a physician), then monitor your breastfed baby for signs of low blood glucose levels such as irritability, sleepiness, poor feeding, fits, low body temperature.

Driving

Can I drive if I have consumed Gliclazide?

Gliclazide can cause low blood sugar levels, which can lead to drowsiness, unconsciousness, confusion. These can be dangerous while driving. Keep a juice or chocolate handy in the car, in case you start feeling uneasy, immediately have the juice or chocolate. Please note that the artificial sweeteners do not help. Consult your doctor whether you can drive a car if you have few or no warning signs of low blood sugar (hypoglycemia).

Alcohol

Can I consume alcohol with Gliclazide?

Avoid the consumption of alcohol while taking this medicine because an intolerance may occur, resulting in flushing, giddiness, nausea, rapid heart rate. Be cautious not to consume alcohol on an empty stomach. Alcohol increases the risk of low blood sugar.

Other General Warnings

Talk to your doctor if

Liver problems
Kidney problems
Any allergies to sulfa containing medicines
This medication may make you more sensitive to the sun's effects. Avoid prolonged sun exposure. Wear protective clothing and use an effective sunscreen when outdoors. Inform your doctor if you become ...
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You have low blood sugar levels as Gliclazide can reduce blood glucose, which can cause symptoms like extreme hunger, headache, nausea, vomiting, sluggishness, sleepiness, restlessness, aggression, re...
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Risk factors for low blood glucose levels are missing your meals, excessive exercise, certain medicines, having more dose of Gliclazide than prescribed by your doctor, alcohol consumption, fasting
When taking this medicine have your meals regularly, never miss or skip a meal
Check your blood glucose regularly and HbA1C every six months

Mode of Action of Gliclazide

How Does It Work?

Insulin moves sugar (glucose) from the blood into the cells. The cells then use it as fuel for energy. In Type 2 diabetes, your body doesn’t make enough insulin or doesn’t utilize insulin properly, so...

Interactions of Gliclazide

Interactions with other medicines

Medicines used to treat fungal infections (Miconazole, Fluconazole)
Medicines used to treat high blood sugar (oral anti-diabetics)
Pain killers or anti-rheumatics, such as Ibuprofen or Phenylbutazone
Medicines used to treat high blood pressure or heart failure (like Captopril or Enalapril)
Antibiotics (like Sulfonamides, Clarithromycin)
Medicines used to treat ulcers in the stomach
Medicines used to treat depression

Interactions with food items

No known interaction.

Dietary Restrictions of Gliclazide

It is advisable to follow a strict diabetic diet and exercise regimen to further improve the overall control of the disease
Excessive exercise should be avoided

Dosage of Gliclazide

Overdose

Symptoms of overdose may include low blood sugar (hypoglycaemia). Contact your doctor immediately.

Missed a Dose

Try to take every dose at the scheduled time. If you miss a dose, take it as soon as you remembere. Do not take the dosage if it is near the time for the next dose; instead, skip the missed dose and c...

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD CCEBDM Diabetology

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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