Fluoxetine
Description
Fluoxetine is an antidepressant that belongs to a class of medicines called Sel
ective Serotonin Reuptake Inhibitors (SSRIs). It is used to help improve mood, reduce anxiety, and manage several mental health conditions, including depression, anxiety disorder, obsessive-compulsive disorder (OCD), phobias, post-traumatic stress disorder (PTSD), and panic disorder. By balancing brain chemicals, Fluoxetine can help you feel more in control of your thoughts and emotions. Fluoxetine works by increasing serotonin levels, a natural chemical in the brain that affects mood, sleep, and emotions. When serotonin levels are balanced, feelings of sadness, panic, or obsessive thoughts are reduced, and overall mental well-being improves. It may take a few weeks of consistent use to notice the full benefits. Take Fluoxetine exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting your doctor, even if you feel better.
Uses
- It is used to treat depression, anxiety disorders, obsessive-compulsive disorder (OCD), phobias, post-traumatic stress disorder (PTSD), and panic disorder.
Contraindications
When should one not use Fluoxetine
Side effects
Common side effects of this drug are:
- Common side effects include nausea, upset stomach, headache, sleep problems, fatigue, nervousness, decreased sexual desire, blurred vision, heart palpitations, or frequent urination. Contact your doctor if side effects persist or worsen....
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You should take Fluoxetine exactly as prescribed and do not change the dose without consulting your doctor.
- You should inform your doctor about all other medications you are taking to avoid interactions.
- You should avoid sudden discontinuation of Fluoxetine, as abrupt discontinuation may cause withdrawal symptoms.
- You should monitor mood changes, especially during the first few weeks, and report any worsening depression, suicidal thoughts, or unusual behavior.
- You should exercise caution if you have a history of seizures, bleeding disorders, or bipolar disorder.
Mode of Action
How Does It Work?
Dosage
Overdose
- An overdose of Fluoxetine can cause symptoms like severe dizziness, rapid heartbeat, vomiting, tremors, agitation, or loss of consciousness. If you suspect an overdose, seek immediate medical help or visit the nearest emergency room, as timely treatment is important to prevent complications....
Missed a Dose
Content Details
Ravindra Ghongade
B. Pharm
Dr. Nikita Toshi
BDS (Bachelor of Dental Surgery), WHO FIDES member
Frequently Asked Questions (FAQs)
Q: How long does it take for Fluoxetine to work?
Q: Can Fluoxetine cause weight gain?
- Some people may experience slight weight changes, but significant weight gain is uncommon. Maintaining a healthy diet and exercise routine is recommended.
Q: Is it safe to stop Fluoxetine suddenly?
Q: Do I need regular blood tests while on Fluoxetine?
- Routine blood tests are not usually required, but your doctor may monitor liver function, electrolytes, or heart health if you have underlying conditions.
References
- U.S. Food and Drug Administration. Fluoxetine tablets, for oral use – Highlights of Prescribing Information [Internet]. 2023 Dec [cited 2025 Dec 08].
- Fluoxetine 20 mg Capsules summary of product characteristics. Electronic Medicines Compendium [Internet]. 2020 [cited 2025 Dec 08].
- CDSCO [Internet]. New Delhi: Ministry of Health & Family Welfare; [cited 2025 Dec 08].