Fluoxetine
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Molecule Summary
| Uses | Anxiety and Mood Disorders |
| Therapy | Anti-Depressant |
| Side Effects | Indigestion, Loss of Appetite, Nausea, Sweating |
Assurance
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Regulated
Molecule Description
Fluoxetine is an antidepressant that belongs to a class of medicines called Selective Serotonin Reuptake Inhibitors (SSRIs). It is used to help improve mood, reduce anxiety, and manage several mental health conditions, including depression, anxiety disorder, obsessive-compulsive disorder (OCD), phobias, post-traumatic stress disorder (PTSD), and panic disorder. By balancing brain chemicals, Fluoxetine can help you feel more in control of your thoughts and emotions.
Fluoxetine works by increasing serotonin levels, a natural chemical in the brain that affects mood, sleep, and emotions. When serotonin levels are balanced, feelings of sadness, panic, or obsessive thoughts are reduced, and overall mental well-being improves. It may take a few weeks of consistent use to notice the full benefits. Take Fluoxetine exactly as prescribed by your doctor. Do not change your dose or stop taking it without consulting your doctor, even if you feel better.
Uses
- It is used to treat depression, anxiety disorders, obsessive-compulsive disorder (OCD), phobias, post-traumatic stress disorder (PTSD), and panic disorder.
Contraindications
When should one not use Fluoxetine
If you are allergic to Fluoxetine.
If you are taking monoamine oxidase inhibitors (MAOIs) or have stopped them within the last 14 days.
If you have a history of serotonin syndrome, avoid using Fluoxetine without medical advice.
If you are taking other medications that increase serotonin levels, consult your doctor before starting Fluoxetine.
If you have severe liver disease.
If you have a known prolonged QT interval or certain heart conditions.
Side effects
Common side effects of this drug are:
- Common side effects include nausea, upset stomach, headache, sleep problems, fatigue, nervousness, decreased sexual desire, blurred vision, heart palpitations, or frequent urination. Contact your doctor if side effects persist or worsen.
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You should take Fluoxetine exactly as prescribed and do not change the dose without consulting your doctor.
- You should inform your doctor about all other medications you are taking to avoid interactions.
- You should avoid sudden discontinuation of Fluoxetine, as abrupt discontinuation may cause withdrawal symptoms.
- You should monitor mood changes, especially during the first few weeks, and report any worsening depression, suicidal thoughts, or unusual behavior.
- You should exercise caution if you have a history of seizures, bleeding disorders, or bipolar disorder.
Mode of Action
How Does It Work?
Fluoxetine works by increasing serotonin levels, a natural chemical in the brain that affects mood, sleep, and emotions. When serotonin levels are balanced, feelings of sadness, panic, or obsessive thoughts are reduced, and overall mental well-being improves. It may take a few weeks of consistent use to notice the full benefits.
Dosage
Overdose
- An overdose of Fluoxetine can cause symptoms like severe dizziness, rapid heartbeat, vomiting, tremors, agitation, or loss of consciousness. If you suspect an overdose, seek immediate medical help or visit the nearest emergency room, as timely treatment is important to prevent complications.
Missed a Dose
If you miss a dose of Fluoxetine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double-dose to make up for the missed one, as this may increase side effects.
Frequently Asked Questions (FAQs)
Articles
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References:
- U.S. Food and Drug Administration. Fluoxetine tablets, for oral use – Highlights of Prescribing Information [Internet]. 2023 Dec [cited 2025 Dec 08].
- Fluoxetine 20 mg Capsules summary of product characteristics. Electronic Medicines Compendium [Internet]. 2020 [cited 2025 Dec 08].
- CDSCO [Internet]. New Delhi: Ministry of Health & Family Welfare; [cited 2025 Dec 08].
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