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Etoposide

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Molecule Summary

Uses
Small cell lung cancer, blood cancer, testicular cancer, lymphatic cancer
Therapy
Anti-Neoplastic
Side Effects
Hair loss, nausea, stomach pain, dizziness
3 Step Quality
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Cash on delivery
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NPPA
Regulated

Molecule Description

Etoposide is an anti-cancer medicine. It is used in the treatment of various types of cancer, such as small cell lung cancer, blood cancer, testicular cancer and lymphatic cancer. It will be given to you in a hospital or clinic by a doctor or nurse as an injection. You should avoid self-injecting.

Uses

For the treatment of small cell lung cancer, blood cancer, testicular cancer, lymphatic cancer.

Contraindications

When should one not use Etoposide

  • If you are allergic to etoposide or any of the ingredients of Etoposide
  • If you have recently taken any live vaccines
  • If you are a breastfeeding mother

Side effects

Common side effects of this drug are:

  • Nausea, vomiting, diarrhoea
  • Constipation, stomach pain
  • Fever, infection, dizziness
  • Skin rash, redness, itching
  • Weakness
  • Hair loss
  • Irregular heartbeats
  • Low blood platelets, anaemia, low WBCs

Precautions and Warnings

Pregnancy

Pregnancy

Etoposide should not be used during pregnancy unless your doctor considers it essential after assessing the benefits over risks. Use effective contraception during treatment. However, if you get pregnant while on treatment, immediately contact your doctor.

Breast Feeding

Breast Feeding

You must not be breastfeeding while on treatment with this medicine, as etoposide passes into breast milk. Consult your doctor.

Driving

Driving

This medicine may make you feel dizzy. Caution is needed while driving or operating machines.

Alcohol

Alcohol

You should avoid consuming alcohol while taking this medicine, as it may worsen the side effects of this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have problems with your heart, liver or kidneys
  • You recently had chemotherapy or radiotherapy
  • You have a condition in which the bone marrow activity is reduced, Myelosuppression.
  • If you develop fever, chills, rapid heart rates, low blood pressure and shortness of breath (anaphylactic reaction), immediately contact the doctor.
  • You have infections.
  • You have a low level of albumin (protein) in your blood.

Mode of Action

How Does It Work?

Etoposide interacts with DNA (genetic material) and causes certain changes in the DNA. This results in problems in DNA synthesis leading to anti-cancer effects.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Etoposide works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.
  • Especially if you are taking medicines to treat heart problems, cancer, fits or are taking painkillers, blood thinners, ciclosporin or have recently taken live vaccines.

Dosage

Overdose

  • This medicine will be given to you by a doctor or nurse. Therefore, it is less likely that you may get an overdose on this medicine. If you experience any symptoms right after taking this medicine, seek medical help.

Missed a Dose

The doctor or nurse usually gives this medicine in the hospital or clinic. Therefore, the chances of missing a dose are less. However, if you feel that a dose has been missed, please inform your doctor and nurse.

Frequently Asked Questions (FAQs)

Etoposide is an anti-cancer medicine.

Etoposide is used for the treatment of small-cell lung cancer, blood cancer, testicular cancer and lymphatic cancer.

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