Disopyramide
Molecule Description
Disopyramide belongs to the class of antiarrhythmic medicines. It helps to corr
ect abnormal and irregular rhythm of heart.
Uses of Disopyramide
- Prevention and treatment of arrhythmias occurring after myocardial infarction
- Maintenance of normal rhythm after electro conversion e.g. atrial fibrillation, atrial flutter
- Persistent ventricular extrasystoles
- Control of arrhythmias following the use of digitalis or similar medicines
- Suppression of arrhythmias during surgical procedures e.g. cardiac catheterization
- Prevention of paroxysmal supraventricular tachycardia
Contraindications of Disopyramide
When should one not use Disopyramide
- Known hypersensitivity to this medicine
- Those with cardiomyopathy (an acquired or hereditary disease of the heart muscle)
- Cardiogenic shock
- Patients with complete heart block
- Glaucoma (increased pressure inside the eyes)
- Predisposition to urinary retention
- Myasthenia gravis (rapid fatigue and weakness of muscles under voluntary control)
- Sinus node disease in the absence of pacemaker in children
Side effects of Disopyramide
Common side effects of this drug are:
- Abnormal heart rhythm
- Dry mouth
- Constipation
- Urinary retention
- Blurred vision
- Double vision
- Worsening of pre-existing glaucoma (eye conditions that can cause blindness)
Precautions and Warnings of Disopyramide
Pregnancy
Q:
Can I take Disopyramide during pregnancy?
A:
You should not take this medicine during pregnancy. It is because the safety of this medicine for use during pregnancy has not been established.
Breast Feeding
Q:
Can I take Disopyramide while breastfeeding?
A:
This medicine passes into breast milk, but the effect on a nursing infant is not known. It is advisable to consult your doctor before breastfeeding.
Driving
Q:
Can I drive if I have consumed Disopyramide?
A:
This medicine may cause dizziness or decreased alertness. If you feel the same, do not drive.
Alcohol
Q:
Can I consume alcohol with Disopyramide?
A:
It is unsafe to consume alcohol with this medicine.
Other General Warnings
Talk to your doctor if
- This medicine may cause low blood sugar if you have diabetes
- Tell your doctor if you have a history of:
- Heart failure
- Decreased kidney or liver function
- Nutrition problems
Mode of Action of Disopyramide
How Does It Work?
The heart sends electrical signals which prompt the heart’s muscles to contract. With every contraction, blood is pumped all over the body. When the electrical signals are disrupted, heart pumping and the rhythmic pattern of the same are affected. This is called arrhythmia. Disopyramide helps in regulating the irregular heartbeats by inhibition of certain abnormal electrical signals generated at heart....
Interactions of Disopyramide
Interactions with other medicines
- Other antiarrhythmic agents
- Phenytoin
- Antimuscarinic medicines
- Beta-blockers
- Verapamil
- Digitalis
- Tricyclic antidepressants
- Rifampicin
- Saquinavir
- Phenytoin
- Ketoconazole
Interactions with food items
No specific interactions with food have been reported yet.
Dosage of Disopyramide
Overdose
Symptoms of Disopyramide overdose are loss of consciousness, fall in blood pressure, respiratory arrest, episodes of temporary cessation of breathing, conduction disturbances of the heart, arrhythmias, slowing down of heartbeats and seizures. In case of an overdose, seek emergency medical care immediately....
Missed a Dose
If you missed any dose, take it as early as you remember. If it is time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of medicine to compensate for a missed one....
Content Details
WRITTEN BY
Dr. Mansi Savla
B. Pharm, PharmD
REVIEWED BY
Dr. Ritu Budania
MBBS, MD (Pharmacology)
Frequently Asked Questions (FAQs)
Q: What should I discuss with my healthcare expert before taking Disopyramide?
- Give a detailed account of your medical and surgical history. Tell your doctor if you have a history of:
- Heart failure
- Decreased kidney or liver function
- Nutrition problems
Q: Any special precautions to be taken while on treatment with this medicine?
A: Inform your doctor if you have diabetes or your potassium levels are not normal. Special precautions should be taken during conduction disorders, liver and kidney impairment. Be cautious if you have a family history of glaucoma.
References
View All
- EMC. Disopyramide. [Accessed on 30.Sep.2019](Online)
- Webmd. Disopyramide. [Accessed on 30.Sep.2019] (Online)
- Mayoclinic. Disopyramide. [Accessed on 30.Sep.2019] (Online)
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Disopyramide. [Updated 2019 Jan 7]
Recent articles
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.