Chlorzoxazone+Tramadol

Uses	Painful muscle spasm
Side Effects	Dizziness, lightheadedness, nausea, vomiting, weakness, fatigue, liver problem, headache, rash

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Molecule Description

Chlorzoxazone+Tramadol is a pain-relieving medicine with muscle relaxant properties. It is used for the treatment of painful muscle spasms associated with musculoskeletal conditions. This medicine is also used to relieve pain after operations and surgeries. Chlorzoxazone+Tramadol is a combination medicine containing chlorzoxazone and tramadol. Chlorzoxazone is a muscle relaxant that reduces muscle spasm and stiffness, and tramadol is an opioid pain reliever that changes how the brain senses pain. Take it as per the dose, duration and frequency recommended by your doctor.

Uses

Chlorzoxazone+Tramadol is used for relieving pain of muscles, joints and bones in conditions such as arthritis, spondylitis and injuries.
It is also used for relieving pain post surgeries and operations.

Contraindications

When should one not use Chlorzoxazone+Tramadol

If you are allergic to chlorzoxazone, tramadol or any ingredient of Chlorzoxazone+Tramadol.
If you have severe breathing problems or acute severe asthma.
If you are taking, or have recently taken, medicines called MAO inhibitors (used for depression).
If you have problems with kidney and liver function.
If you are pregnant.

Side effects

Common side effects of this drug are:

Dizziness
Lightheadedness
Nausea
Vomiting
Weakness
Fatigue
Liver problem
Headache
Rash

Precautions and Warnings

Pregnancy

It is unsafe to take this medicine during pregnancy. Hence, it should not be taken by pregnant women. Taking this medicine during pregnancy can cause defects in the baby's heart or even delay of delivery or increase the risk of bleeding.

Breast Feeding

Components of this medicine passes into the breast milk and there is limited information regarding the safety of this medicine during breastfeeding. Hence it is advised not to use this medicine if you are breastfeeding.

Driving

It is not advised to drive or use machines while using this medicine as components of this medicine may cause dizziness and even affect your ability to drive.

Alcohol

It is advised to avoid the consumption of alcohol during the treatment as it may worsen your liver problems and other side effects.

Other General Warnings

Talk to your doctor if

You have kidney or liver problems.
You have heart problems like high blood pressure, heart failure.
You are an elderly patient or taking diuretics or have a kidney disorder, this medicine can increase the risk of kidney failure.
Your doctor may ask you to do renal function tests for the same.
You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease or you are passing black tarry stools.
You have asthma as this medicine can worsen the same.
You have Systemic lupus erythematosus (an autoimmune disease).
You are an alcoholic then concomitant use of this medicine can damage the liver.
You have disorders related to blood like clotting problems and anaemia.
You have skin rashes & lesions after taking this medicine.

Mode of Action

How Does It Work?

Chlorzoxazone+Tramadol works by the combined action of its two components. Tramadol is an opioid pain reliever that acts on the brain and spinal cord to change how pain is felt. Chlorzoxazone is a muscle relaxant which works by blocking the signals of painful sensation through the nerve to the brain and reduces pain and stiffness.

Interactions

Interactions with other medicines

Do not take other opioid pain relievers, sleeping pills, sedatives or alcohol with this medicine without asking your doctor, as they can increase drowsiness and breathing problems.
If you are taking medicines for high blood pressure, this medicine can interfere with their effect.
Medicines like water pill can lead to kidney damage when taken along with it.
Caution is needed if you are taking medicines to treat heart failure.
This medicine can increase the levels of lithium and methotrexate. Discuss with your doctor before starting the treatment.
Medicines used to modify immune response during organ transplant like ciclosporin & tacrolimus can result in kidney damage if taken with this medicine.
Increased risk of stomach ulcers or bleeding when taken with steroids or other pain relief medicines like Aspirin.
There is a risk of bleeding if you are taking blood-thinning medicines like Warfarin and Coumarin.
Increased risk of fits if you are taking this medicine with antibiotics like Levofloxacin and Ciprofloxacin.
If you are taking medicines to treat diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat and hunger pangs.
Medicines used to treat fits, seizures & depression-like Phenobarbital, Carbamazepine, Phenytoin and Clonazepam should be used with caution as this medicine can increase the side effects of these medicines.
Medicine used to treat gout-like Probenecid, medicines used to treat a bacterial infection like Chloramphenicol, Rifampicin and HIV infections like Zidovudine should be used cautiously.

Dosage

Overdose

Taking Chlorzoxazone+Tramadol in high doses may result in symptoms of overdose like headache, nausea, vomiting and stomach pain. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a Dose

Do not take a double dose if you have missed the dose, take the next dose as soon as you remember.

Frequently Asked Questions (FAQs)

No, it is not safe to take any other medicines to relieve pain along with this medicine. Concomitant use of painkillers can cause adverse effects like gastrointestinal bleeding and liver damage.

Gastritis is a condition that affects the lining of the stomach causing pain and inflammation. It is caused due to infection, use of certain medicines, injury, etc. Chlorzoxazone+Tramadol is a medicine used to relieve pain due to muscle spasms, so it may not be effective for gastritis.

No, the medicine must not be taken for headaches or conditions other than what it is prescribed for. Chlorzoxazone+Tramadol is used for relieving pain of musculoskeletal conditions.