Paxonil 12.5 Mg Tablet 10
10 Tablet(s) in StripWe do not sell this product
Made by
ALTEUS BIOGENICS PVT LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Paroxetine(12.5 Mg) |
| Uses | Depression, Social Anxiety Disorder, Panic Disorder, Premenstrual Dysphoric Disorder (PMS), Obsessive Compulsive Disorder (OCD), Post-Traumatic Stress Disorder (PTSD), Anxiety, Postmenopausal symptoms |
| Therapy | Anti-depressant |
| Side effects | Heartburn, Seizure, Vision problems, Belching, Decreased appetite, Increased passing gas, Difficulty urinating, Abdomen pain, Inappropriate behaviour, Restlessness or irritability, Black (tar) coloured stools, Bloody or red-coloured vomit, Dizziness, Headache, Breathlessness, Panic attack, Body pain, Chills, Cough, Difficulty breathing, Runny nose, Nasal congestion, Sneezing, Throat soreness, Difficulty sleeping, Difficulty concentrating, Weakness (generalised) |
Assurance
available
Regulated
Medical Description
Paxonil 12.5 mg Tablet is a prescription antidepressant medication. It is a combination of clonazepam and paroxetine. The mode of action of Paxonil 12.5 mg tablets is through the mood enhancement caused by raising the level of chemical messengers in the brain. It also soothes the brain by reducing nerve cell activity that is aberrant or excessive.
Side effects of Paxonil 12.5 mg tablets include nausea, vomiting, confusion, memory impairment, decreased sexual drive, confusion, and delayed ejaculation.
Paxonil 12.5 mg tablets are contraindicated in case of liver disease. It is important to disclose any other medications being taken before starting treatment with Paxonil 12.5 mg, as some of them may affect the effectiveness or modify the way this medicine works.
Directions of use of Paxonil 12.5 mg tablets should be strictly followed. It can be taken with or without food. The medicine should ideally be taken at the same time every day to maintain a consistent level of medicine in the blood. It is to continue the medication unless advised otherwise by a doctor. Suddenly stopping the use of this medication can cause withdrawal symptoms.
Uses
- Paxonil 12.5 mg tablet is used to treat, regulate, prevent, and improve the symptoms of the diseases listed below.
- Depression
- Panic disorders
- Obsessive-Compulsive Disorder (OCD, a disorder causing unwanted and obsessive thoughts that lead you to perform repetitive behaviours)
- Post-Traumatic Stress Disorder (PTSD, anxiety caused after experiencing a traumatic event)
- Social Anxiety Disorder (an extreme fear of being watched or judged by others in social situations)
- Generalised Anxiety Disorder
- Premenstrual Dysphoric Disorder (PMS, severe depression symptoms, irritability, and tension before menstruation).
- Seizure disorders
Contraindications
- If you have any of the following conditions, you should not take Paxonil 12.5 mg tablets:
- Concomitant use of monoamine oxidase inhibitors (MAOIs) to treat depression
- Acute narrow-angle glaucoma
- Hypersensitivity to clonazepam, paroxetine or any other component of Paxonil 12.5 mg tablets
- Liver disease
- Kidney disease
- Bipolar Disorder
- Heart disease
Side effects
- Serious side effects of Paxonil 12.5 mg tablets include:
- Heartburn
- Seizure
- Vision problems
- Decreased appetite
- Difficulty urinating
- Abdomen pain
- Inappropriate behaviour
- Restlessness or irritability
- Black (tar) coloured stools
- Bloody or red-coloured vomit
- Dizziness
- Headache
- Breathlessness
- Chills
- Cough
- Nasal congestion
- Throat soreness
- Difficulty sleeping
- Difficulty concentrating
- Weakness (generalised)
- Rare side effects of Paxonil 12.5 mg tablets include:
- Dilated pupils and sensitivity to light
- Loss of coordination
- Loose motion
- Hallucination
- Night terrors
- Skin rash
- Anxiety
- Chest pain
- Dry mouth
- Memory loss
- Nosebleeds
- Indigestion
- Body discoloration
- Arrhythmia (irregular heartbeat)
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have suicidal ideas and actions while taking this medication.
- You have disturbances of bleeding. Paxonil 12.5 mg tablets can induce bruising and bleeding that is unexpected. As a result, if you have severe active bleeding or a hemorrhagic diathesis (tendency to bleed easily), this medicine should be used with caution.
- You have epilepsy. If you experience seizures, Paxonil 12.5 mg tablets should be used with caution as it may worsen your condition.
- You have episodes of mania. Paxonil 12.5 mg tablets may cause or ignite mania in some people..
- You have hyponatremia. This is a condition in which the salt content in the blood is abnormally low. In some circumstances, Paxonil 12.5 mg tablets may cause hyponatraemia. This danger is particularly significant in the elderly, those who are volume-depleted (have less fluid in their bodies) or taking diuretics.
- You have bone fractures. Paxonil 12.5 mg tablets should be used cautiously if you have low bone mineral density, as it may induce fractures. If you have unexplained bone pain, tenderness, swelling, or bruising, tell your doctor.
- You have sexual dysfunction. Paxonil 12.5 mg tablets can induce sexual dysfunction such as diminished sexual desire, delayed ejaculation, and erectile dysfunction.
- You are a child under 18 years of age. Safety and efficacy of Paxonil 12.5 mg tablets have not been clinically demonstrated on children.
- You are an older adult. Due to the increased potential of side effects, Paxonil 12.5 mg Tablet should be used with great caution in the elderly.
Directions for Use
- The dosage and duration of the Paxonil 12.5 mg tablet is prescribed by your doctor. Paxonil 12.5 mg tablets can be taken with or without food. However, it is recommended to take it after meals to prevent nausea. Swallow the entire tablet with a glass of water. Do not crush, bite or break. It is advised to take a tablet daily at a fixed time.
- Withdrawal symptoms may occur if you stop taking Paxonil 12.5 mg suddenly without seeing your doctor. If you notice any changes in your behaviour or have thoughts of harming yourself, see your doctor at once.
Storage and disposal
Cold temperature is advised for the storage of Paxonil 12.5 mg tablets, far from direct sunlight and humidity.
If there are disposal commands at the package deal, please comply with the commands. Unless otherwise directed, do not dump or pour medicine down the toilet or into the drainage system. For further information on how to safely dispose of Paxonil 12.5 mg tablets, see your pharmacist or doctor.
Dosage
Overdose
Agitation, hallucinations, convulsions, nausea, drowsiness, fainting, dizziness, confusion, difficulty breathing, fast or slow heartbeat, and seizures are the most common complications of Paxonil 12.5 mg tablet overdose.
Never exceed the recommended dosage. In the event of a Paxonil 12.5 mg tablet overdose, seek immediate medical attention.
Missed a Dose
A missed dose of a Paxonil 12.5 mg tablet should be taken as soon as you remember. In case you remember a missing adose of this medicine when it is already time for the next one, don't take the missed dose to compensate. Avoid double doses and continue with the regular schedule.
Mode of Action
How Does It Work?
Paroxetine and clonazepam, which have mood-enhancing and anxiety-reducing properties, are combined in Paxonil 12.5 mg tablets. Paroxetine is an SSRI (selective serotonin reuptake inhibitor) that raises serotonin levels, a chemical messenger that enhances mood. Clonazepam is a benzodiazepine (BZD) that enhances the function of GABA, a chemical messenger that inhibits aberrant nerve cell activity in the brain.
Interactions
Interactions with other medicines
- Paxonil 12.5 mg tablets may interact with the medications and products listed below:
- Other antidepressants like monoamine oxidase inhibitors (MOAIs)
- Linezolid (antibiotic)
- Lithium (used to treat bipolar disorders)
- Ondansetron (to prevent nausea and vomiting)
- Warfarin (anticoagulant)
- Aspirin (pain killer)
- Paracetamol (pain killer)
- Chlorpheniramine (anti-allergic)
- Dextromethorphan (cough suppressant)
- Tramadol (opioid pain killer)
- Cetirizine (anti-allergic)
- Codeine (morphine pain killer)
- Quinidine (treat irregular heartbeats)
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Manufacturer Details
Brand:PAXONIL
Vendor Details
Fulfillment Information: Paxonil 12.5 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- K Shingjergji, R Celebi, J Scholtes, M Dumontier. Relation Extraction from DailyMed Structured Product Labels by Optimally Combining Crowd, Experts and Machines [Internet] 2021. dailymed.nlm.nih.gov [cited 15 Feb 2022] -
- A Kesselheim, M Mello, J Avorn. FDA Regulation of Off-label Drug Promotion Under Attack [Internet] 2013. www.accessdata.fda.gov [cited 15 Feb 2022] -
- Drug Maker Found Liable Despite FDA Warning Label [Internet]. 2009. www.accessdata.fda.gov [cited 15 Feb 2022] -
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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
