Depaxil Cr Plus 12.5mg Tablets
10 Tablet(s) in StripWe do not sell this product
Made by
ALKEM LABORATORIES LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Paroxetine(12.5 Mg)+Clonazepam(0.5 Mg) |
| Uses | Anxiety, major depressive disorder |
| Therapy | Anti-depressant |
| Side effects | Constipation, reduced heart rate, nightmares, cold palms and soles, uncoordinated body movements, sweating, flu-like symptoms. |
Assurance
available
Regulated
Medical Description
Depaxil Cr Plus tablet is a prescription medication used to treat panic attacks, depression and mood disorders. It is composed of two active ingredients: paroxetine and clonazepam. Depaxil Cr Plus tablets' mode of action is to increase the amount of serotonin, a chemical substance that improves mood. It also works by reducing the abnormal activity of the nerve cells in the brain.
Reducing the symptoms of post-traumatic stress disorder (PSTD) as well as the symptoms of various mood disorders such as the feeling of sadness, loss of interest, anger, panic attacks, loneliness, etc., are some of the uses of Depaxil Cr Plus tablets. The symptoms and intensity of these disorders vary from person to person. Dizziness, drowsiness, fatigue, etc., are some common side effects of Depaxil Cr Plus tablets.
Try to follow your doctor's direction for using Depaxil Cr Plus tablets. This medicine should be used exactly in the prescribed dose and duration. This medicine may cause physical dependence if used for a long duration or in people who have a history of addiction. Inform your complete medical history and current treatments to your doctor, as Depaxil Cr Plus tablets can not be used in certain conditions.
Uses
- The main uses of Depaxil Cr Plus tablets are
- Treatment of depression.
- Treatment of panic disorder.
- Treatment of anxiety disorder.
- Rapid treatment for Post-traumatic stress disorder (PTSD)
Contraindications
- If you have allergies to any components of the Depaxil Cr Plus tablet
- If you have a previous history of alcohol or recreational drug addiction.
- If you are already using another antidepressant, anti-anxiety or sedatives, as they can interfere, they can cause adverse reactions.
- If you are pregnant.
- If you are breastfeeding.
- If you have acute eye disorder like narrow-angle glaucoma.
- If you have liver disease.
- If you have bleeding issues or you are on a blood thinner. Depaxil Cr Plus tablets can increase bleeding.
- If you have any heart condition.
- Note - Not advised for children below 18 years of age.
Side effects
- Nausea
- Vomiting
- Diarrhoea
- Memory impairment
- Uncoordinated body movements
- Tiredness
- Drowsiness
- Dizziness
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have to use any medications like painkillers that cause sedation or tranquillisation.
- You have any trouble breathing.
- You have kidney-related issues. You may need dose adjustments.
- You have any seizure disorder (fits) and are using anti-epileptic medicines.
- You have to use herbal medicines or supplements.
- You are experiencing these side effects persistently.
- Note: The effects of this medicine are exaggerated in older patients, so use it with caution. Generally, side effects do not need any medical treatment if taken as prescribed.
Directions for Use
- Take the Depaxil Cr Plus tablet in the advised dosage and at the same time every day.
- Try not to exceed the dosage, even if you cannot feel any changes.
- You can take Depaxil Cr Plus tablets with or without consuming food.
- Swallow the whole tablet with a glass of water without breaking or chewing it.
- It is better not to take it with other medicines without notifying your doctor.
- Do not suddenly stop taking Depaxil Cr Plus tablet, as it can have adverse effects
Storage and disposal
Store Depaxil Cr Plus tablet in dry conditions and over 25 degrees Celcius. Keep these tablets away from wet surfaces, direct sunlight, and humid conditions. Store Depaxil Cr Plus tablet away from children and pets.
Throw away the tablet's packaging after using it. It is better to check the expiration date before taking the tablet. Do not use the Depaxil Cr Plus tablet if it's past the expiration.
Dosage
Overdose
Depaxil Cr Plus tablet overdose can cause dizziness, muscle shaking, tremors, agitation, convulsion, nausea, vomiting, and electrolyte imbalance. If you overdose on the Depaxil Cr Plus tablet and experience any of these symptoms, immediately seek emergency medical treatment from a hospital close to
Missed a Dose
If you have missed a dose of Depaxil Cr Plus tablet, take it as soon as possible. If you recall missing a dose of this medicine when it's already time to take the next tablet, then skip the missed dose and take the next Depaxil Cr Plus tablet.
Consult your doctor if you have any confusion about the dosage or if you missed more than a few doses. Do not take both tablets together as it can cause some unwanted effe
Mode of Action
How Does It Work?
The Depaxil Cr Plus tablet has paroxetine and clonazepam. It increases serotonin levels in the brain by stopping its reuptake by nerve cells. Serotonin is a chemical messenger responsible for stabilising mood, causing happy feelings, etc. It can also aid in sleeping, eating, and digestion.
Clonazepam belongs to the class of benzodiazepine medicines. Functions by increasing the action of a chemical messenger in the brain known as GABA (gamma-aminobutyric acid). It reduces the abnormal or excessive activity of nerve cells in the brain. It is responsible for its sedation properties. It may not affect the levels of GABA in the brain.
Interactions
Interactions with other medicines
- Do not use other anti-anxiety and mood disorder medications and medications like linezolid, moclobemide, selegiline, etc., along with this medicine. It can cause some serious reactions similar to an overdose of Depaxil Cr Plus tablet.
- Using opiates or narcotic pain relievers such as codeine and tramadol with Depaxil Cr Plus tablets can increase the side effects such as drowsiness, dizziness, etc.
- If you are using Anti-epileptic medicines for seizure disorders (fits) such as phenytoin, notify your doctor as Depaxil Cr Plus tablet can increase the effects of these medications.
- Certain anti-depression medications such as MAO inhibitors along with Depaxil Cr Plus tablets should not be used within 14 days of each other. It can lead to severe reactions.
Interactions with food items
- Try to avoid eating grapefruit or drinking its juice. It can increase the level of Depaxil Cr Plus tablet in the blood.
- Limit having coffee or caffeine-containing products such as cola, energy drinks, excessive chocolate, etc. The effects of caffeine can reduce the calming effects of Depaxil Cr Plus tablets.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:DEPAXIL PLUS
Manufacturer Name:ALKEM LABORATORIES LTD
Address:<p>1. Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.</p>
Country of Origin:India
Vendor Details
Fulfillment Information: Depaxil Cr Plus 12.5mg Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Pollack MH;Simon NM;Worthington JJ;Doyle AL;Peters P;Toshkov F;Otto MW; Combined paroxetine and Clonazepam treatment strategies compared to paroxetine monotherapy for panic disorder [Internet]. Journal of psychopharmacology (Oxford, England). U.S. National Library of Medicine;[cited 2022 Mar 2]. Available from
- Evaluation of clonazepam and Paroxetine for Panic Disorder With Depression - Full Text View [Internet]. Full Text View - ClinicalTrials.gov. [cited 2022 Mar 2]. Available from:
- CDSCO [Internet]. cdscoonline.gov.in. 2022 [cited 2022 Mar 2] - Available from:
- Clonazepam and paroxetine for rapid treatment of post-traumatic stress disorder - full text view [Internet]. Full Text View - ClinicalTrials.gov. [cited 2022 Mar 2]. Available from:
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
