Tenofovir Disoproxil

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Molecule Description

Tenofovir is an antiviral (more specifically an antiretroviral) medicine that is used in the treatment of HIV or Hepatitis B Virus.

Uses

HIV
Hepatitis B virus infection

Contraindications

When should one not use Tenofovir Disoproxil

Those having allergic reaction to Tenofovir.

Side effects

Common side effects of this drug are:

Nausea, vomiting
Stomach pain
Diarrhea
Fever
Cough
Weakness
Dizziness
Insomnia
Depressed mood
Itching or rash
Symptoms of lactic acidosis – muscle pain, breathing difficulty, fast heartbeats
Kidney complaints – decreased urination, easy bruising
Liver problems – nausea, stomach pain, itching, tiredness, loss of hunger
Sore throat, flu symptoms
Unusual bleeding, easy bruising
Signs of new infection – fever, diarrhea, stomach pain, night sweats
Chest pain, dry cough
Rapid heart rate, irritable

Precautions and Warnings

Pregnancy

Limited data is available on the safety of this medicine during pregnancy, consult your doctor before taking Tenofovir.

Breast Feeding

It may affect newborn nursing infants; you should not breastfeed a child while on treatment with Tenofovir. Consult your doctor before starting this medication if you are breastfeeding.

Driving

Tenofovir can cause dizziness. If you feel dizzy after taking this medicine, do not drive.

Alcohol

Avoid alcohol while on the medication of Tenofovir, as it may increase the risk of liver damage.

Other General Warnings

Talk to your doctor if

Age above 65
You have kidney or liver disease
You have any bone problems
It cannot prevent transmission of infection. Hence protection to be taken accordingly

Mode of Action

How Does It Work?

Tenofovir is an antiviral medicine, it controls the growth of certain viruses (belonging to retrovirus group) and therefore it is used in the treatment of HIV or Hepatitis B Virus.

Interactions

Interactions with other medicines

Tenofovir can cause kidney problems, especially when taken with few medicines (antivirals, antibiotics) at the same time
Inform your physician if you are taking any of the following medicines:
Atazanavir
Darunavir
Didanosine
Ledipasvir
Lopinavir

Interactions with food items

No information is available on dietary restrictions while you are taking Tenofovir, consult your doctor or pharmacist for further details.

Dietary Restrictions

No information is available on dietary restrictions while you are taking Tenofovir, consult your doctor or pharmacist for details.

Dosage

Overdose

If you happen to take an overdose of the medicine, kindly seek emergency medical care immediately. The effects of an overdose may be lethal and need immediate medical attention. The symptoms of overdose can be nausea, vomiting, diarrhea, dizziness, etc.

Missed a Dose

It is ideal not to miss a dose. If you miss a dose, take medicine as soon as you remember the missed dose. If it is almost time for your next dose, don’t take the missed dose and go back to the regular dosing schedule. Do not take a double dose.

Frequently Asked Questions (FAQs)

Take medicine after meals. Tenofovir oral powder should not be mixed with liquid. Mix it with some soft food like yogurt, baby food, etc. When the medicine is used for a child, inform the doctor if there is a change in weight of the child, because the dose of the drug needs to be adjusted accordingly.

Inform the doctor about your detailed medical, surgical and allergy history. Inform your physician if you have liver disease or kidney disease.