Pantoprazole

Molecule Description

Pantoprazole is a proton pump inhibitor used to treat conditions such as gastro

esophageal reflux disease (GERD) in adults and children over 5 years old, allowing the esophagus to heal and preventing further damage. It is also used in managing conditions where the stomach produces excessive acid, such as Zollinger-Ellison syndrome. Pantoprazole works by decreasing stomach acid production through its proton pump inhibition. Administered as delayed-release tablets or granules, Pantoprazole should be taken as prescribed by a healthcare provider. For GERD treatment, it is usually taken once a day, while conditions with excessive stomach acid may require twice-daily dosing. Pantoprazole can be taken with or without food, and granules are typically taken 30 minutes before a meal, mixed with applesauce or apple juice. Pantoprazole may cause side effects like headache, nausea, and joint pain. Prolonged use may increase the risk of certain complications, and patients are advised not to exceed the recommended duration without consulting their healthcare provider. Special precautions include discussing allergies, existing medical conditions, and other medications with a healthcare provider before starting Pantoprazole. Pregnant or breastfeeding individuals should inform their doctors, and those over 70 years of age should be cautious about prolonged use. Pantoprazole may interact with certain medications, and these should be discussed with healthcare providers. Patients are urged to take Pantoprazole as directed, not altering the dosage or frequency without consulting their doctor. If a dose is missed, it should be taken as soon as remembered, unless it's close to the next scheduled dose.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Pantoprazole

Stomach ulcer
Ulcer in the first part of intestine
A peculiar infection of the stomach called Helicobacter Pylori infection. Here it is used along with antibiotics
Treating symptoms like heartburn, acid regurgitation associated to gastro-oesophageal reflux disease
Zollinger-Ellison syndrome
It can be used alone or with other medicines that decrease or neutralize acid secretion

Contraindications of Pantoprazole

When should one not use Pantoprazole

If you have any allergic reaction to Pantoprazole or other proton pump inhibitors
If you are on Rilpivirine or Atazanavir or other anti-HIV medications
If you are on Methotrexate
You have/ are suspected of having stomach cancer. There are studies that link Pantoprazole to stomach cancer. It is important to share if you have any personal or family history of stomach cancer

Side effects of Pantoprazole

Common side effects of this drug are:

Headache
Constipation or diarrhea along with flatulence
Dry mouth
Stomach pain
Fatigue
Skin rash
Sore throat
Serious skin conditions: blistering of the skin, erosion of nose, mouth, lips, genitals (Steven Johnson syndrome) and sensitivity to light
Increased risk of infections in the long term use
Fracture of the hip, wrist or spine
Skin turning yellow (severe damage to liver cells, jaundice)
Altered sense of taste
Disturbances in vision such as blurred vision
Decreased sodium and magnesium levels in blood

Precautions and Warnings of Pantoprazole

Pregnancy

Can I take Pantoprazole during pregnancy?

There is no adequate information from the use of Pantoprazole in pregnant women. If you are pregnant, you should use this medicine only if your doctor considers the benefit for you more significant than the potential risk for your unborn baby.

Breast Feeding

Can I take Pantoprazole while breastfeeding?

Pantoprazole passes into human milk. If you are breastfeeding, ask your doctor before taking this medicine.

Driving

Can I drive if I have consumed Pantoprazole?

Pantoprazole has a negligible influence on the ability to drive. If you experience side effects like dizziness or disturbed vision, you should avoid driving.

Alcohol

Can I consume alcohol with Pantoprazole?

No interaction between alcohol and Pantoprazole has been reported. However, alcohol is known to increase acidity and can make your acidity worse.

Other General Warnings

Talk to your doctor if

If you have serious liver issues. In case of an increase of liver enzymes, the treatment should be stopped
If you have low levels of vitamin B12 (like Cobalamin). Pantoprazole is known to cause reduced absorption of vitamin B12 in the long term
If on exposure to sun you get rashes on your skin, stop your treatment with Pantoprazole and inform your doctor as soon as you can
It may cause Clostridium difficle associated diarrhea and malabsorption if taken for a long term. Therefore, it should be taken only on doctor’s advice

Mode of Action of Pantoprazole

How Does It Work?

A pump called the proton pump in the stomach is responsible for the secretion of stomach acids. Pantoprazole binds to this proton pump in stomach cells and blocks the acid secretion. Therefore, it is ...

Interactions of Pantoprazole

Interactions with other medicines

Medicines such as Itraconazole, Ketoconazole (used to treat fungal infections)
Medicines such as Erlotinib, Methotrexate (used for certain types of cancer)
Medicines given in HIV/ AIDS patients (such as Nelfinavir, Tenofovir, Atazanavir, Rilpivirine, etc.)
Warfarin and Phenprocoumon, these affect the thickening or thinning of the blood

Interactions with food items

To be taken on an empty stomach. There are no known interactions with food or beverages. However, nicotine, caffeine (coffee, tea, chocolate, and cola) and alcohol can stimulate stomach acid or delay ...

Dietary Restrictions of Pantoprazole

Not to be taken with food. Pantoprazole should be taken in the morning on an empty stomach.

Dosage of Pantoprazole

Missed a Dose

If you missed any dose, take it as soon as you remember. Skip the missed dose if it is almost time for the next dose and continue your regular dosing schedule. Do not take a more dose to compensate fo...

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD CCEBDM Diabetology

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What is Pantoprazole used for?

A: Pantoprazole is commonly used to treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome by reducing stomach acid production.

Q: How should I take Pantoprazole?

A: Pantoprazole dosage depends on the specific condition being treated, and it's essential to follow the prescribed regimen provided by your healthcare provider.

Q: Can Pantoprazole be used for heartburn?

A: Yes, Pantoprazole is used in treating heartburn associated with GERD by reducing stomach acid, providing relief, and promoting healing of the esophagus.

Q: What are the side effects of Pantoprazole?

A: Common side effects may include headache, nausea, and joint pain. Serious side effects are rare but may include blistering skin, irregular heartbeat, and severe diarrhea. Consult your doctor if you experience any unusual symptoms.

Q: Is Pantoprazole safe during pregnancy?

A: Pregnant individuals should consult their doctor before using Pantoprazole. It is crucial to discuss potential risks and benefits to determine its appropriateness during pregnancy.

Q: Can I take Pantoprazole with other medications?

A: Certain medications may interact with Pantoprazole. Inform your healthcare provider about all medications, including over-the-counter and herbal supplements, before starting Pantoprazole.

Q: How long can I take Pantoprazole?

A: The duration of Pantoprazole use depends on the condition being treated. Consult your doctor for guidance, and avoid exceeding the recommended duration without professional advice.

Q: Can Pantoprazole be taken with food?

A: Pantoprazole can be taken with or without food, depending on the specific instructions from your healthcare provider. Follow the prescribed guidelines for the best results.

Q: What should I do if I miss a dose of Pantoprazole?

A: If you miss a dose, take it as soon as you remember, unless it's close to the next scheduled dose. Do not double the dose to make up for a missed one.

Q: Are there any dietary restrictions while taking Pantoprazole?

A: Unless otherwise advised by your doctor, you can continue with your normal diet while taking Pantoprazole.

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Last Updated on: 20 Feb 2024 | 03:58 PM (IST)

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जीरा (Cumin in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू!

एक स्वस्थ जीवन जीने और वज़न कम करने के लिए हम अलग-अलग तरीकों और स्वास्थ्यवर्धक काढ़ों जैसी चीज़ें आज़माते रहते हैं। अनगिनत स्वास्थ्य लाभों का वादा करने के अलावा, ये शरीर को डिटॉक्स करने और वज़न घटाने में मदद करने का भी दावा करते हैं। लेकिन एक पेय (ड्रिंक) है जो ऐसा करने में कामयाब

मशरूम (Mushroom in Hindi) के उपयोग, फ़ायदे, और न्यूट्रिशनल वैल्यू

परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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