Flutamide

Molecule Description

Flutamide is anti-androgenic medicine which blocks testosterone (male sex hormo

ne) action in the body.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Flutamide

It is used in the treatment of prostate cancer
It is also used after surgical removal of testis (castration)

Contraindications of Flutamide

When should one not use Flutamide

If you are allergic to Flutamide.

Side effects of Flutamide

Common side effects of this drug are:

Yellow discolouration of skin, nails, eyes
Clay coloured stools
Dark urine
Upper stomach pain
loss of appetite
Itching over the skin
Nausea and vomiting
Breathing difficulty
Tenderness or mild breast swelling
Swelling over face or lips
Tiredness
Sleepiness
Loose motions

Precautions and Warnings of Flutamide

Pregnancy

Can I take Flutamide during pregnancy?

This medicine is used only to treat male medical condition. Hence not prescribed to women.

Breast Feeding

Can I take Flutamide while breastfeeding?

This medicine is used only to treat male medical condition. Hence it is not prescribed to women.

Driving

Can I drive if I have consumed Flutamide?

It causes tiredness, dizziness or confusion. You should avoid driving during this course of treatment.

Alcohol

Can I consume alcohol with Flutamide?

You should not consume alcohol in large quantities while on treatment with this medicine.

Other General Warnings

Talk to your doctor if

You have heart disease, liver disease, kidney disease, brittle bone or breathlessness
You have diabetes

Mode of Action of Flutamide

How Does It Work?

Flutamide prevents the action of male sex hormones in the body, thereby decreasing the growth of prostate cancer.

Interactions of Flutamide

Interactions with other medicines

Blood thinners (Warfarin)
Theophylline (to treat breathing problem)
Medicines that can affect your liver or electrical activity of your heart
Medicines to treat cancers like Leuprorelin

Interactions with food items

No information is available on interactions of Flutamide when taken with food, consult your doctor or pharmacist for further information.

Dietary Restrictions of Flutamide

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further details.

Dosage of Flutamide

Overdose

Symptoms of this medicine's overdose include decreased activity, slow breathing, dizziness, watering eyes, upraised body hair, decreased appetite or vomiting. Consult with your doctor immediately.

Missed a Dose

If you miss a dose, do not take the double dose to catch up the skipped dose. Follow your regular dosing schedule.

Content Details

WRITTEN BY

Dr. Arpit Verma

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Flutamide?

You must inform your doctor if you are allergic to Flutamide
Tell your doctor if you have liver disease
If you are G6PD enzyme deficient
If you suffer from Hemoglobin M disease
If you smoke
Inform your doctor if you are taking any other medicines

Q: What should I avoid while taking Flutamide?

Flutamide can cause diarrhea. Hence avoid taking laxatives and dairy products while you are taking Flutamide
Caregivers must maintain hygiene, wash hands thoroughly, wear gloves while cleaning up the body fluids, trash, linen and laundry.
Flutamide can pass in body fluids (stool, urine and vomit). Soiled clothes and linen must be washed separately

Q: Any precautions I should take when on this medicine?

Drink more fluids to prevent dehydration in case of diarrhoea
Avoid direct exposure to excessive sunlight and use sunscreen when outdoors as this medicine can make your skin sensitive to sunlight

Q: Do I need to undergo any lab tests during this treatment?

A: Your doctor may ask you to have regular blood tests such as liver function tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine or stomach pain as this medicine can cause liver damage.

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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