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Eptifibatide

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Molecule Summary

Uses
Prevention of heart attack (unstable angina, non-Q-wave myocardial infarction)
Therapy
Anti-Platelet
Side Effects
Bleeding, low blood pressure, anaemia
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Molecule Description

Eptifibatide is an antiplatelet medicine. Eptifibatide is used to prevent heart attack in adults. It works by preventing the formation of blood clots. Eptifibatide will be given to you by your doctor or nurse. Do not self-inject it. Before starting this medicine, inform your doctor if you are pregnant/breastfeeding and about your complete medical history.

Uses

  • Eptifibatide is used to prevent heart attack in adults with:
  • unstable angina (a type of heart-related chest pain that usually occurs while resting).
  • individuals who have had a non-Q-wave myocardial infarction (a type of heart attack), with chest pain in the last 24 hours and with abnormalities on the electrocardiogram (ECG) or signs of heart problems in the blood.

Contraindications

When should one not use Eptifibatide

  • If you are allergic to eptifibatide or any of the other ingredients of Eptifibatide.
  • If you have been or are scheduled for treatment with another medicine of the same type as Eptifibatide. If you are not sure what these medicines are, please confirm with your doctor.
  • If you recently had abnormal bleeding from your stomach, intestines, bladder or other organs.
  • If you have a history of stroke in the past 30 days or any haemorrhagic stroke.
  • If you had a brain tumour or any condition that affects the blood vessels around the brain.
  • If you had a major operation or severe injury/trauma in the past 6 weeks.
  • If you have a history of bleeding problems.
  • If you have or had a low blood platelet count.
  • If you have or had severe high blood pressure.
  • If you have or had severe kidney or liver problems.

Side effects

Common side effects of this drug are:

  • Bleeding
  • Low blood pressure
  • Inflammation of a vein
  • Decreased number of red blood cells (anaemia)

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information on the effect of Eptifibatide during pregnancy. This medicine should not be used in pregnant women unless recommended by the doctor.

Breast Feeding

Breast Feeding

No information is available if Eptifibatide passes into human breast milk. It is recommended that breastfeeding should be discontinued during treatment with this medicine.

Driving

Driving

There is limited information on the effect of Eptifibatide on driving ability. If you experience any effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

Alcohol

There is limited information available on the interaction of alcohol with Eptifibatide. Ask your doctor for advice on alcohol intake along with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You are elderly or have low body weight.
  • You have kidney disorders.
  • You are taking other medicines for treating other health conditions like non-steroidal anti-inflammatory medicines (for treating pain, inflammation and swelling), dipyridamole, prostacyclin, dabigatran, clopidogrel, ticlopidine (for preventing blood clots), reteplase (to break up or dissolve blood clots), sulfinpyrazone (for treating gouty arthritis), medicines for treating irregular heartbeats.

Mode of Action

How Does It Work?

Eptifibatide is a platelet aggregation inhibitor. It prevents the formation of blood clots by preventing the platelets from sticking together. This reduces the risk of a blood clot forming and helps prevent another heart attack.

Interactions

Interactions with other medicines

  • Some medicines can affect the way Eptifibatide works or this medicine itself can reduce the effectiveness of other medicines taken at the same time.
  • Tell your doctor about all medicines, supplements or herbals you are currently taking or might take to avoid any possible interaction.
  • Particular care should be taken if you are taking medicines like oral anticoagulants (used to thin the blood) or medicines that prevent blood clots, like warfarin, dipyridamole, ticlopidine and aspirin.

Dosage

Overdose

Since Eptifibatide will be given to you by a doctor or nurse, the chances of an overdose are unlikely.

Missed a Dose

It is unlikely that a dose of Eptifibatide will be missed if you are monitored in a healthcare setup. However, if you have missed taking a dose of the medicine, inform the doctor or nurse immediately.

Frequently Asked Questions (FAQs)

Eptifibatide is used to prevent heart attack in adults with: • unstable angina (a type of heart-related chest pain that usually occurs while resting). • individuals who have had a non-Q-wave myocardial infarction (a type of heart attack), with chest pain in the last 24 hours and with abnormalities on the electrocardiogram (ECG) or signs of heart problems in the blood.

Eptifibatide is a platelet aggregation inhibitor. It prevents the formation of blood clots by preventing the platelets from sticking together. This reduces the risk of a blood clot forming and helps prevent another heart attack.

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