Adefovir Dipivoxil

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Molecule Description

Adefovir is a nucleotide analog reverse-transcriptase inhibitor which belongs to class of antiviral medicines.

Uses

Adefovir benefits in Chronic Hepatitis B virus infection, for people who are 12 years of age or older.

Contraindications

When should one not use Adefovir Dipivoxil

Allergy to this Adefovir or any of its ingredients.

Side effects

Common side effects of this drug are:

Diarrhea or indigestion
Mild stomach pain, nausea
Headache
Vomiting
Weakness
Rash
Itching

Precautions and Warnings

Pregnancy

Limited information is available about its safety in pregnancy, hence do not take this medicine unless considered essential by your physician.

Breast Feeding

It is unexplored if this medicine passes into breast milk. You should not take this medicine if you are breastfeeding. Seek for safer alternative during breastfeeding.

Driving

This medicine does not have any influence on your ability to drive.

Alcohol

Avoid consumption of alcohol while taking Adefovir because it may increase side effects significantly.

Other General Warnings

Talk to your doctor if

Your age is 65 or more
Kidney or liver disease

Mode of Action

How Does It Work?

Adefovir works by preventing viral cells from multiplying in the body and also from infecting new cells. Thus, it reduces the viral load in the blood.

Interactions

Interactions with other medicines

Nucleoside analogs (like Zidovudine, Stavudine, and Lamivudine) because it may increase the risk of lactic acidosis or cause severe liver problems
Aminoglycosides (like Amikacin, Gentamicin, Kanamycin, Neomycin, and Tobramycin), Amphotericin B, Cyclosporine, NSAIDs (like Diclofenac, Aceclofenac, Naproxen, Piroxicam, Ibuprofen, etc.) because these may increase the risk of kidney problems

Interactions with food items

No information is available on interaction with food while you are taking Adefovir. Consult your doctor or pharmacist for further details.

Dietary Restrictions

No information is available on dietary restrictions while you are taking Adefovir. Consult your doctor or pharmacist for further details.

Dosage

Overdose

Overdose of Adefovir may include symptoms such as an upset stomach, vomiting, gas, loose bowel movements, or loss of appetite. Seek immediate medical help if you suspect an overdose of this medicine.

Missed a Dose

If you have missed the Adefovir regular dose, then take the missed dose as soon as you remember it. If it is almost the time for the next dose, then skip the missed dose and continue with the next dose. Don't take a double dose if you missed a dose.

Frequently Asked Questions (FAQs)

Tell your doctor if you have conditions such as history of kidney problems, abnormal liver function, and history of lactic acidosis if any. Inform if you are a known case of high blood pressure and if you also have HIV infection.

Take this medicine with or without food as recommended by the doctor.

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