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Prothiaden 75mg Strip Of 10 Tablets

10 Tablet(s) in Strip
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Prothiaden 75 MG Description

Tablet Prothiaden 75 mg contains dosulepin hydrochloride 75 mg. It is an antidepressant and an anxiolytic drug. It belongs to the class of medicines called tricyclic antidepressants. Depression and a

nxiety disorder are problems related to mental health. They may be due to changes in certain chemicals in the brain. This leads to persistent sadness, loss of interest in one’s environment, excessive worrying, fear and inability to sleep due to anxiety. Prothiaden increases the levels of these chemicals called serotonin and regulates the mood. This helps treat depression and anxiety disorder. Prothiaden is sometimes used for relieving nerve pains in fibromyalgia. It is occasionally used to prevent migraine though it is a long-term prophylactic treatment. You should continue taking Prothiaden for the duration and the dosage as advised by your doctor. If you stop the medicine suddenly, your symptoms can reappear, or there may be serious side effects.


Product Summary

Offer Price₹320.94
You Save₹43.76 (12% on MRP)
ContainsDosulepin / Dothiepin(75.0 Mg)
UsesDepression, anxiety disorders
Side effectsSleepiness, tremors, dryness of mouth, difficulty in passing urine
Check more medicines with composition as Dosulepin / Dothiepin(75.0 Mg)

Uses of Prothiaden 75 MG

  • Depression
  • Anxiety disorder
  • Fibromyalgia
  • Prevention of migraine

Contraindications of Prothiaden 75 MG

  • Known hypersensitivity to Prothiaden or other tricyclic antidepressants
  • Kidney disease
  • Liver disease
  • Heart disease
  • Prostate problem
  • Thyroid disorder
  • Glaucoma
  • Epilepsy
  • Porphyria
  • Pregnancy or planning for pregnancy
  • Breast-feeding mothers
  • Children
  • Adolescents under 18 years
  • Thoughts of suicide

Side effects of Prothiaden 75 MG

  • Common side effects
  • Drowsiness
  • Dizziness
  • Dryness of mouth
  • Blurred vision
  • Constipation
  • Nausea, indigestion
  • Difficulty in passing urine
  • A sudden drop in blood pressure
  • Headache
  • Rare and severe side effects are:
  • Hypersensitivity reactions in the form of Rashes and hives
  • Tightness in the chest
  • Swelling of the face, tongue and eyes
  • Increased heart rate
  • Yellow discolouration of the eyes and skin
  • Frequent muscle cramps
  • Persistent weakness or confusion
  • Pain and redness in the eyes
  • Convulsions
  • Suicidal behaviour
  • Bone marrow depression exhibiting unusual bruising, mouth ulcers and sore throat
  • Contact your doctor or emergency services immediately if you experience any of these side effects.

Precautions and Warnings of Prothiaden 75 MG



Can I take Prothiaden 75 mg during pregnancy?
Studies have shown a risk of harm to the unborn child if this medicine is taken during pregnancy. If you are pregnant or planning to conceive during the treatment, discuss the risks and benefits of continuing the treatment with your doctor.

Breast Feeding

Can I take Prothiaden 75 mg while breastfeeding?
Prothiaden is to be avoided while breastfeeding the child as it passes through the breast milk. Discuss the possible risks and benefits of continuing it while breastfeeding with your doctor.


Can I drive if I have taken Prothiaden 75 mg?
Prothiaden induces sleepiness and altered alertness levels. Therefore, your ability to drive safely may be affected. It is best to avoid cycling or driving till you know how this medicine makes you feel.


Can I consume alcohol with the Prothiaden 75 mg?
Having alcohol while on treatment with Prothiaden can make you feel sleepier. It may also increase the risk of severe side effects such as dizziness, breathing problems and loss of consciousness.

Other General Warnings

Talk to your doctor if
  • Prothiaden should be taken strictly on the advice of the doctor. You must complete the course of the treatment as recommended. You should not stop the medicine suddenly, as this may lead to the develo...
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Mode of Action of Prothiaden 75 MG

How Does It Work?

Prothiaden acts on certain chemicals in the brain. These chemicals, known as serotonin, are responsible for regulating mood. A reduction in serotonin levels can result in depression and anxiety disord...
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Directions for Use of Prothiaden 75 MG

  • Always take the tablet as advised by your doctor.
  • Keep the timing and the dosage of the medicine as is recommended in the prescription.
  • Take the tablet as a whole without cutting or crushing it and swallow it with water.
  • Take the tablet out of the strip at the time of having it.
  • The tablet can be had with or without food as food doesn’t affect the absorption of Prothiaden. There is no stomach upset with Prothiaden.
  • It is usually taken before bedtime as it may cause sleepiness.
  • Check the expiry date on the strip of tablets before starting the course of medication.
  • You should not stop the medicine without discussing it with your doctor.
  • If you stop the medicine without completing the course recommended by the doctor, your symptoms may reappear.
  • Inform your family members about the possible adverse effects and whom to contact in case of such events.

Interactions of Prothiaden 75 MG

Interactions with other medicines

  • Opioids such as codeine, hydrocodone, morphine
  • Selective serotonin reuptake inhibitors (SSRI)
  • Monoamine oxidase inhibitors (MAO)
  • Ephedrine, pseudoephedrine, adrenaline, noradrenaline
  • Amylobarbitone
  • Phenobarbitone
  • Methylphenidate
  • Levothyroxine
  • Guanethidine
  • Terfenadine
  • Terfenadine
  • Astemizole
  • Sotalol

Interactions with food items

  • It is best to avoid alcohol consumption while on this medication. Alcohol can worsen the side effects of the medicine, such as drowsiness and dizziness. You can eat your usual diet.

Storage and disposal of Prothiaden 75 MG

Store the medicine in a cool, dry place, preferably at a temperature below 300 C. Protect it from moisture, heat and light. It should be stored away from the reach of children. Expired or left-over t...
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Dosage of Prothiaden 75 MG


The symptoms of overdose are dryness of mouth, unsteadiness, sleepiness, tremors, convulsions, delirium, urinary retention, hallucinations, blurred vision, breathing problem, and unconsciousness. Call...
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Missed a Dose

If you take Prothiaden once a day at bedtime and have missed the dose, take the next dose at the usual time. If you take Prothiaden two or three times a day and have missed a dose, then take the table...
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Content Details


Dr. Tulika Singh



Dr. Anuj Tiwari

MBBS, DNB Medicine

Frequently Asked Questions (FAQs)


Q: Is Prothiaden habit forming?

A: Prothiaden is not habit-forming. However, if it is stopped suddenly, it may cause withdrawal symptoms that can be unpleasant or even serious. These symptoms can be headache, restlessness, inability to fall asleep, flu-like symptoms, tremors or convulsions.

Q: How long shall I have to take Prothiaden?

A: You should take Prothiaden for the duration and the dosage as prescribed by your doctor. When it is prescribed for depression, the doctor usually continues the medicine for several months after your symptoms have subsided. Stopping it before completing the course may cause the symptoms to reappear.

Q: Will it take a long time for me to feel better after starting the treatment with Prothiaden?

A: It usually takes four to six weeks for Prothiaden to have a full effect against depression, anxiety or nerve pain. Consult your doctor if you feel worsening of symptoms during the initial treatment period.

Q: How do I cope with the headaches I have while taking Prothiaden?

A: You should drink plenty of fluids, take adequate rest, avoid smoking and consuming alcohol. You should consult your doctor if your headaches are severe or persist for longer than one week.
Product Details
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Last Updated on: 15 Apr 2022 | 05:38 PM (IST)

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The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.
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