Lenalidomide

Molecule Description

Lenalidomide is utilized for the treatment of multiple myeloma. This medicine b

elongs to a group of medications which affect how your immune system works (immuno-modulatory).

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Lenalidomide

Multiple myeloma (a type of cancer which affects a certain kind of white blood cell, called the plasma cell. These cells collect in the bone marrow and divide, becoming out of control. This can damage...
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Myelodysplastic syndromes (the blood cells become abnormal and do not function properly)
Mantle cell lymphoma (B-cells grow in an uncontrolled way and build up in the lymph tissue, bone marrow or blood)
Follicular Lymphoma or Marginal Zone Lymphoma

Contraindications of Lenalidomide

When should one not use Lenalidomide

Allergic to this medicine
Kidney impairment
Liver impairment

Side effects of Lenalidomide

Common side effects of this drug are:

Blood clots in the veins (serious side effect)
Low blood counts (anaemia, low neutrophils, low platelets, low WBCs)
Bleeding or bruising in the absence of injury
Chest pain or leg pain
Low levels of potassium and sodium in the blood
Infections of all types
Shortness of breath
Constipation, diarrhea, nausea
Redness of skin, rashes
Blurred vision
Clouding of your eye (cataract)
Kidney problems
Increase in liver test results
Changes to a protein in the blood that can cause swelling of the arteries (vasculitis)
Increases in your blood sugar level (diabetes)
Decreases in your blood sugar
Headache
Dry skin

Precautions and Warnings of Lenalidomide

Pregnancy

Can I take Lenalidomide during pregnancy?

It is adviced not to use this medicine during pregnancy as this medicine may harm your unborn baby
Inform your doctor if you are planning pregnancy or are pregnant

Breast Feeding

Can I take Lenalidomide while breastfeeding?

It is not advised to breastfeed as it is unknown if it passes into human milk.

Driving

Can I drive if I have consumed Lenalidomide?

If you feel dizzy, tired, sleepy, have vertigo or blurred vision, do not drive.

Alcohol

Can I consume alcohol with Lenalidomide?

Alcohol consumption increases the adverse effects of the medicine.

Other General Warnings

Talk to your doctor if

You have had blood clots in the past - you have an increased risk of developing blood clots in the veins and arteries during treatment
You have any signs of an infection, such as a cough or fever
You have or have ever had a previous viral infection, particularly Hepatitis B infection
You have kidney problems
You have had a heart attack

Mode of Action of Lenalidomide

How Does It Work?

Lenalidomide acts by inhibiting the growth of new blood cells in tumors; it stimulates the immune system and decreases the cell growth factor. It alters certain genes present in the cancer cells and p...

Interactions of Lenalidomide

Interactions with other medicines

Some medicines used to prevent pregnancy such as oral contraceptives, as they may stop working
Some medicines used for heart problems – such as Digoxin
Some medicines used to thin the blood – such as Warfarin

Interactions with food items

Multiple myeloma can cause anemia
Patient should have iron rich diet like beans, chickpeas, lentils, nuts, spinach, and other leafy greens
A person should also include sources of vitamin C with non-heme iron like bell peppers, oranges, berries, and lemon juice, in their diet to improve absorption

Dosage of Lenalidomide

Overdose

Overdose may cause symptoms like nausea, vomiting, diarrhoea
Peripheral neuropathy may develop in an overdose
Bone marrow suppression occurs which will lead to anaemia, low WBC count, low immunity, low platelet count, and easy bleeding/ bruising tendency
Inform your doctor immediately in case you suspect an overdose

Missed a Dose

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Abhishek B L

MBBS, MD (Pharmacology)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Lenalidomide?

A: Give a detailed account of your medical and surgical history. The doctor should also know about other health supplements like herbal medications, nutritional supplements that you may take before starting this medication.

Q: What are the precautions should I take while on this medicine?

A: The dosage regimen of the medicine should be followed regularly. Any miscalculation in the dose will have severe effects.

Q: Why there is a bleeding tendency while taking this medicine?

A: Lenalidomide is known to decrease the platelet count in the body (platelets are required to stop bleeding), so there are chances of bleeding tendency while taking this medicine.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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