Filgrastim

Molecule Description

Filgrastim is a ‘growth factor’ used to prevent infections and fever due to dec

reased white blood cells as a result of cancer treatment. It belongs to a class of medicines called G-‘CSF’ or Granulocyte- ‘Colony Stimulating Factors.’

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Filgrastim

Stimulate the production of a type of white blood cells (granulocytes)
Granulocytes are one of the kinds of white blood cells and constitute neutrophils, basophils and eosinophils. The main function of all these granulocytes is to fight infections
The primary purpose of Filgastrim is to increase the numbers of cells that fight infections because cancer medicines are powerful and kill the blood cells along with cancer cells
To mobilize stem cells in patients undergoing bone marrow transplants (peripheral blood stem cell mobilization). Stem cells are a kind of mother cells produced in the bone marrow from which all blood ...
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Filgrastim can be used to mobilize these stem cells from bone marrow into the blood then collected, stored and later used for bone marrow transplantation (in disease and cancers that destroy bone marr...
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To prevent the risk of infections in certain immune compromised patients e.g., HIV patients
Filgrastim is not a medicine to treat any particular type of cancer

Contraindications of Filgrastim

When should one not use Filgrastim

If you have allergy to Filgrastim or any of the components of the medicine.

Side effects of Filgrastim

Common side effects of this drug are:

Feeling sick (nausea), vomiting, headache
Fever, fatigue, hair loss
Swelling and soreness of the lining of the digestive tract anywhere between the mouth and the anus
Low red blood cells and thrombocytes
Infections of the nose, throat, lung and urinary tract, feeling dizzy, sleeping problems, decreased sensation, tingling and numbness of hands and feet, low or high blood pressure, cough and coughing b...
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Skin rashes and mouth ulcers and stomach (due to rejection of transplanted bone marrow, a condition known as graft versus host disease), high uric acid levels, allergic reactions, bone loss or thinnin...
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Severe allergic reaction like- fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat, with or without itching, rashes, skin peeling; cough fever and difficulty in bre...
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Precautions and Warnings of Filgrastim

Pregnancy

Can I take Filgrastim during pregnancy?

Though there are no adequate studies done on Filgrastim, this medicine has the potential to harm the baby and should not be given in pregnant women.

Breast Feeding

Can I take Filgrastim while breastfeeding?

It is unknown if Filgrastim is secreted in breast milk. It should be used in breastfeeding mothers only if necessary and cannot be replaced.

Driving

Can I drive if I have consumed Filgrastim?

Filgrastim has little or no effect on your ability to drive. It can cause occasional dizziness and caution is recommended.

Alcohol

Can I consume alcohol with Filgrastim?

Alcohol lowers immunity and increases the risk of infections. As cancer patients are at increased risk for infections and Filgrastim is used to prevent infections, consumption of alcohol is not advised.

Other General Warnings

Talk to your doctor if

You have sickle cell anemia (a genetic disorder causing death of red blood cells)
You have bone loss or thinning (osteoporosis)
You have unusual bleeding or bruising
You have sudden allergy, rashes or breathing problems, swelling of face and feet and blood in the urine (signs of kidney damage)

Mode of Action of Filgrastim

How Does It Work?

Filgrastim works on the bone marrow, which is the center for producing all types of blood cells. This medicine stimulates the production of white blood cells, particularly neutrophils, which are essen...

Interactions of Filgrastim

Interactions with other medicines

Filgrastim should not be used up to 24 hours before or after taking cancer treatment (medicines or radiation).

Interactions with food items

Filgastrim can be taken with or without food but preferably on an empty stomach.

Dietary Restrictions of Filgrastim

Drink plenty of water.

Dosage of Filgrastim

Overdose

Overdose may cause breathing trouble, dizziness or stomach problems. Contact your doctor as soon as possible.

Missed a Dose

Contact your doctor if you missed a dose and take his advice on when to take the next dose. Do not double the dose.

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Is there anything else I need to know before taking Filgrastim?

Dosage of Filgrastim depends on factors such as height, weight, general health and other problems. Take this medicine exactly as prescribed by the doctor. Do not self-medicate or self-adjust the dose
There may be many side effects with Filgrastim because the patient already has cancer and is undergoing treatment. But do not worry, as most of these effects can be managed and disappear once you stop...
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Filgrastim should be stored in a refrigerator and taken out 30 minutes before administration. Do not use the medicine if it is kept out of a refrigerator for more than 15 days
Filgrastim is given as an injection below your skin (subcutaneous) or as slow drip through your veins (intravenous drip)
Keep in mind that this medicine may interfere with some lab tests (like bone imaging tests) and give false test results

Q: Does Filgrastim cure cancer?

Filgrastim does not cure any cancer. It is a supportive treatment in cancer patients which help to fight infections due to the treatment
It will allow you to continue and complete the full course of cancer treatment and increases your chances of cure
Filgrastim is a substitute for the naturally occurring substance in our body called ‘Granulocyte-Colony Stimulating Factor,’ which increases the production of white blood cells. This growth factor is ...
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References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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